Tetramethylpyrazine from Pleurotus geesteranus.


Shen, H.S., Liu, H., Chen, J.-C., Shao, S., Zhu, H., Tsao, R., and Zhou, T. (2015). "Tetramethylpyrazine from Pleurotus geesteranus.", Natural Product Communications, 10(9), pp. 1553-1554.


For the first time, the bioactive compound tetramethylpyrazine (TMP) was isolated and identified from the culture of Pleurotus geesteranus Singer. Its identification was confirmed unambiguously by identical retention time and mass spectrum to those of a TMP standard. The TMP content in P. geesteranus from solid culture was up to 8.04 g.kg-1ds. This finding provides a novel natural way to produce TMP and will lead to new value added mushroom products with nutraceutical functions.

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