Dr. Thomas Netticadan

Image Thomas Netticadan
Research Scientist

Investigate the cardiovascular benefits of Canadian food crops

Agriculture and Agri-Food Canada
Canadian Centre for Agri-Food in Health and Medicine, Winnipeg

Current research and/or projects

Overall research goal 

To examine the potential of foods, food-derived extracts and purified components in preventing the development of obesity/diabetes, hypertension and heart failure by utilizing cell culture models and animal models.

 

Projects

Potential of oat derived compounds in preventing the development of hypertension and heart disease in the spontaneously hypertensive rat.

Potential of whole flaxseed and flaxseed derived fractions in preventing the development of heart disease in rats subjected to coronary artery occlusion.

Potential of edible oils in preventing the development of obesity and heart disease in the high fat-fed rat.

Potential of polyphenols in preventing the development of ischemic heart disease in rats subjected to coronary artery ligation.

Potential of fatty acids and polyphenols in preventing cardiomyocyte (heart muscle cell) death and dysfunction.

Education and awards

PhD, University of Bombay, India

Postdoctoral studies, Institut National de la Santé et de la  Recherche Médicale, France.

Postdoctoral studies, University of Western Ontario, Canada.

Key publications

  1. Louis, X.L., Thandapilly, S.J., Yu, L., Wojciechowski, P., Yang, T., Stringer, D.M., Douville, J.M., Cheung, D.Y.C., Massaeli, H., Zhang, S., Wigle, J., Kardami, E., Zahradka, P., and Netticadan, T. (2009). "Resveratrol prevents norepinephrine induced hypertrophy in adult cardiomyocytes.", 6th Canadian Oxidative Stress Conference, Winnipeg, MB, Canada, May 7-10, 2009, pp. 100.

    2009 - View publication details

  2. Behbahani, J., Kopilas, M.A., Wojciechowski, P., Thandapilly, S.J., Netticadan, T., and Anderson, H.D. (2009). "Blood pressure independent correction of resistance artery structure but not intrinsic wall stiffness by resveratrol in the spontaneously hypertensive rat.", Canadian Journal of Cardiology, 25(Suppl. 1B), pp. 30B. (Abstract)

    2009 - View publication details

  3. Wojciechowski, P., Juric, D., Yao, X.-H., Rathi, S., and Netticadan, T. (2008). "Serial examination of sarcoplasmic reticulum function in cardiac hypertrophy due to pressure overload.", Journal of Cardiac Failure, 14(6, Suppl. 11), pp. S15. (Abstract)

    2008 - View publication details

  4. Cantor, E.J.F., Mancini, E.V., Seth, R., Yao, X.-H., and Netticadan, T. (2003). "Oxidative stress and heart disease: cardiac dysfunction, nutrition, and gene therapy.", Current Hypertension Reports, 5(3), pp. 215-220.

    2003 - View publication details

  5. Dhalla, N.S., Temsah, R.M., and Netticadan, T. (2000). "Role of oxidative stress in cardiovascular diseases.", Journal of Hypertension, 18(6), pp. 655-673.

    2000 - View publication details

Contact

Research facility

Morden Research and Development Centre
Route 100, Unit 100-101
Morden, MB R6M 1Y5
Canada

Expertise

Food›Nutrition›Health Benefits

Affiliations

Adjunct Professor, Department of Physiology and Pathophysiology, University of Manitoba

Language

English