Dr. Michel Girard

Mark JK, Dionne S, Cyr TD, Boucher S, Girard M, Hefford MA. Utility of standard pharmacopeial and nonpharmacopeial methods in distinguishing folded, unfolded, and process variant forms of interferon α-2. Journal of Pharmaceutical Sciences. 101 (10): 3672-3686 (2012).

Boucher S, Kane A, Girard M. Qualitative and quantitative assessment of marketed erythropoiesis-stimulating agents by capillary electrophoresis. Journal of Pharmaceutical and Biomedical Analysis. 71: 207– 213 (2012).

Girard M, Puerta A, Diez-Masa JC, de Frutos M. High Resolution Separation Methods for the Determination of Intact Human Erythropoiesis Stimulating Agents. A review. Analytica Chimica Acta, 713: 7- 22 (2012); doi:10.1016/j.aca.2011.11.041

Lorbetskie B, Wang J, Gravel C, Allen C, Walsh M, Rinfret A, Li X, Girard M. Optimization and qualification of a quantitative reversed-phase HPLC method for hemagglutinin in influenza preparations and its comparative evaluation with biochemical assays. Vaccine, 29(18):3377-3389 (2011).

Larocque L, Bliu A, Xu R, Diress A, Wang J, Lin R, He R, Girard M, Li X. Bioactivity Determination of Native and Variant Forms of Therapeutic Interferons. Journal of Biomedicine and Biotechnology, Vol. 2011, Article ID 174615, 11 pages (2011); doi:10.1155/2011/174615.

Gravel C, Li C, Wang J, Hashem AM, Jaentschke B, Xu K-W, Lorbetskie B, Gingras G, Aubin Y, Van Domselaar G, Girard M, He R,  Li X.  Qualitative and quantitative analyses of virtually all subtypes of influenza A and B viral neuraminidases using antibodies targeting the universally conserved sequences. Vaccine, 28(36): 5774-5784 (2010).

Garcia- Cañas V, Lorbetskie B, Cyr TD, Hefford MA, Smith S, Girard M. Approach to the profiling and characterization of influenza vaccine constituents by the combined use of size-exclusion chromatography, gel electrophoresis and mass spectrometry. Biologicals, 38:294-302 (2010).

Diress A, Lorbetskie B, Larocque L, Li X, Alteen M, Isbrucker R, Girard M. Study of aggregation, denaturation and reduction of interferon alpha-2 products by size-exclusion high-performance liquid chromatography with fluorescence detection and biological assays.  Journal of Chromatography A, 1217:3297-3306 (2010).

Storms SM, Feltus A, Barker AR, Joly MA, Girard M. Determination of Somatropin Charged Variants by Capillary Zone Electrophoresis: Optimisation, Verification and Implementation of the European Pharmacopoeia Method.  PharmEuropa Scientific Notes, 2009-1: 25-35 (2009).

Nunnally B, Park SS, Patel K, Hong M, Zhang X, Wang SX, Rener B, Reed-Bogan A, Salas-Solano O, Lau W, Girard M, Carnegie H, Garcia-Cañas V, Cheng KC, Zeng M, Ruesch M, Frazier R, Jochheim C, Natarajan K, Jessop K, Saeed M, Moffatt F, Madren S, Thiam S, Altria K. A Series of Collaborations between Various Pharmaceutical Companies and Regulatory Authorities Concerning the Analysis of Biomolecules Using Capillary Electrophoresis: Additional Instruments/Buffer. Chromatographia, 66P:955-961 (2007).

García-Cañas V, Lorbetskie B., Bertrand D., Cyr T.D. and Girard M. Selective and quantitative detection of influenza virus proteins in commercial vaccines using two-dimensional high performance liquid chromatography and fluorescence detection. Analytical Chemistry, 79:3164-3172 (2007).