Ryan S. Austin, PhD

Chercheur Scientifique

Research Scientist and Adjunct Professor in Genome Biology and Bioinformatics

Agriculture et Agroalimentaire Canada

Centre de recherche et de développement de London

Énoncés de recherches/projets

1. Régulation transcriptionnelle génétique et épigénétique des gènes de stress abiotiques chez les plantes.

2. Cartographie des traits génétiques dans les cultures avec séquençage de prochaine génération.

Prix et études

Doctorat, Biologie du génome et bioinformatique, Université de Toronto, 2009

BSc., Honneurs Biologié, Université de Guelph, 1997

Principales publications

Saatian, B., Austin, R.S., Tian, G., Chen, C., Nguyen, V., Kohalmi, S.E., Geelen, D., Cui, Y. (2018). Analysis of a novel mutant allele of GSL8 reveals its key roles in cytokinesis and symplastic trafficking in Arabidopsis. BMC Plant Biology, [online] 18(1), http://dx.doi.org/10.1186/s12870-018-1515-y
2018 - Consulter les détails de la publication
Duwadi, K., Austin, R.S., Mainali, H.R., Bett, K., Marsolais, F., Dhaubhadel, S. (2018). Slow darkening of pinto bean seed coat is associated with significant metabolite and transcript differences related to proanthocyanidin biosynthesis. BMC Genomics, [online] 19(1), http://dx.doi.org/10.1186/s12864-018-4550-z
2018 - Consulter les détails de la publication
Chen C, Li C, Wang Y, Renaud J, Tian G, Kambhampati S, Saatian B, Nguyen V, Hannoufa A, Marsolais F, Yuan ZC, Yu K, Austin RS, Liu J, Kohalmi SE, Wu K6, Huang S, Cui Y (2017). "Cytosolic acetyl-CoA promotes histone acetylation predominantly at H3K27 in Arabidopsis". Nature Plants. 3(10):814-824. doi: 10.1038/s41477-017-0023-7. Epub 2017 Sep 25.
2017 - Consulter les détails de la publication
Xiao J, Jin R, Yu X, Shen M, Wagner JD, Pai A, Song C, Zhuang M, Klasfeld S,
He C, Santos AM, Helliwell C, Pruneda-Paz JL, Kay SA, Lin X, Cui S, Garcia MF,
Clarenz O, Goodrich J, Zhang X, Austin RS, Bonasio R, Wagner D. Cis and trans
determinants of epigenetic silencing by Polycomb repressive complex 2 in
Arabidopsis. Nat Genet. 2017 Oct;49(10):1546-1552. doi: 10.1038/ng.3937. Epub
2017 Aug 21. PubMed PMID: 28825728.
2017 - Consulter les détails de la publication
Keegan Leckie, Shawn Hoogstra, Ellen Hamilton, Ryan S. Austin. Transcriptional regulation of cell-type specific gene expression in the Arabidopsis root. Inventing The Future: Symposium on Synthetic Biology 2.0 Western University London 2017/07/28 - 2017/07/28
2017 - Consulter les détails de la publication
Dastmalchi, M., Chapman, P., Yu, J., Austin, R.S. and Dhaubhadel, S. (2017) Transcriptomic evidence for the control of soybean root isoflavonoid content by regulation of overlapping phenylpropanoid pathways. BMC Genomics, 18:70 doi 10.1186/s12864-016-3463-y
2017 - Consulter les détails de la publication
Hossain, M.S., Shrestha, A., Zhong, S., Miri, M., Austin, R.S., Sato, S., Ross, L., Huebert, T., Tromas, A., Torres-Jerez, I., Tang, Y., Udvardi, M., Murray, J.D., Szczyglowski, K. (2016). Lotus japonicus NF-YA1 plays an essential role during nodule differentiation and targets members of the SHI/STY gene family. Molecular Plant-Microbe Interactions, [online] 29(12), 950-964. http://dx.doi.org/10.1094/MPMI-10-16-0206-R
2016 - Consulter les détails de la publication
Kambhampati S, Pandurangan S, Renaud JB, Austin RS, Sumarah MW, Marsolais F (2016) Combined transcriptomic and metabolomic approaches provide new insights into C/N partitioning in roots of Arabidopsis thaliana. Poster presentation. CSPB/CSHS 2017. Vancouver, July 4-7
2016 - Consulter les détails de la publication
Austin, R. S., Hiu, S., Waese, J., Ierullo, M., Pasha, A., Wang, T. T., Fan, J., Foong, C., Breit, R., Desveaux, D., Moses, A. and Provart, N. J. (2016), New BAR tools for mining expression data and exploring Cis-elements in Arabidopsis thaliana. Plant J, 88: 490–504. doi:10.1111/tpj.13261
2016 - Consulter les détails de la publication
Dhaubhadel, S., Austin, R. S., Marsolais, F., Chen, L., Bett, K., Islam, N. S., and Mainali, H. R. (2016) Seed coat transcriptome analysis of two pinto bean cultivars that differ in post-harvest seed coat darkening identifies candidate slow darkening genes. 10th Canadian Pulse Research Workshop, Winnipeg, Manitoba, Canada
2016 - Consulter les détails de la publication
Dhaubhadel, S., Austin, R.S., Marsolais, F., Chen, L., Bett, K., Islam, N.S. and Mainali, H.R.M. (2016) Seed coat transcriptome analysis of two pinto bean cultivars that differ in post-harvest seed coat darkening identifies candidate slow darkening genes. 10th Canadian Pulse Research Workshop, Winnipeg, MB, Oct 25-28.
2016 - Consulter les détails de la publication
Dhaubhadel, S., Austin, R.S., Marsolais, F., Chen, L., Bett, K., Islam, N.S. and Mainali, H.R.M. (2016) Seed coat transcriptome analysis of two pinto bean cultivars that differ in post-harvest seed coat darkening identifies candidate slow darkening genes. 10th Canadian Pulse Research Workshop, Winnipeg, MB, Oct 25-28.
2016 - Consulter les détails de la publication
Gao, R., Austin, R.S., Amyot, L., Hannoufa, A. (2016). Comparative transcriptome investigation of global gene expression changes caused by miR156 overexpression in Medicago sativa, 17(1), http://dx.doi.org/10.1186/s12864-016-3014-6
2016 - Consulter les détails de la publication
Kambhampati S, Pandurangan S , Renaud J, Austin R, Sumarah M, Marsolais F (2016) Combined transcriptome and metabolome analysis of asparagine treated Arabidopsis roots provide new insights into N metabolism. Oral presentation. Plant Biotech 2016. Kingston, June 19-21
2016 - Consulter les détails de la publication
Elhiti, M., Wang, H.Y., Austin, R.S., Chen, B., Brown, D.C.W., et Wang, A.M. (2016). « Generation of chemically induced mutations using in vitro propagated shoot tip tissues for genetic improvement of fruit trees. », Plant Cell, Tissue and Organ Culture: Journal of Plant Biotechnology, 124(2), p. 447-452. doi : 10.1007/s11240-015-0894-0
2016 - Consulter les détails de la publication
Bett, K.E., Stonehouse, R.G., Miklas, P.N., Dhaubhadel, S., Austin, R.S., et Marsolais, F. (2015). « Is the slow-darkening gene another allele at P? », Bean Improvement Cooperatives 2015, Niagara Falls, ON, Canada, November 1-4, 2015. (Résumé)
2015 - Consulter les détails de la publication
Dhaubhadel, S., Austin, R.S., Marsolais, F., Mainali, H.R., P-Behnami, S., Pajak, A., et Chen, L. (2014). « Seed coat RNAseq analysis of two Pinto bean cultivars that differ in post-harvest seed coat darkening. », Joint conference of the 6th International Food Legumes Research Conference (IFLRC VI) and 7th International Conference on Legume Genetics and Genomics (ICLGG VII), Saskatoon, SK, Canada, July 6-11, 2014.
2014 - Consulter les détails de la publication
Kambhampati, S., Pandurangan, S., Pajak, A., Austin, R.S., et Marsolais, F. (2014). « Transcriptional responses to exogenous asparagine in Arabidopsis roots. », Eastern Regional Meeting of the Canadian Society of Plant Biologists, Guelph, ON, Canada, November 28-29, 2014. (Affiche)
2014 - Consulter les détails de la publication
Bergin, F., Leckie, K., Croft, M., et Austin, R.S. (2014). « Cell-type specific chromatin dynamics in the Arabidopsis Root. », 25th International Conference on Arabidopsis Research, Vancouver, BC, Canada, July 28-August 1, 2014, #296. (Affiche)
2014 - Consulter les détails de la publication
Austin, R.S. (2014). « Applications of NGS to crop research and development. », Canadian NGS Symposium, Toronto ON, Canada, September 25,2014. (Présentation)
2014 - Consulter les détails de la publication