Ryan S. Austin, PhD

Image Ryan Austin
Chercheur Scientifique

Research Scientist and Adjunct Professor in Genome Biology and Bioinformatics

Énoncés de recherches/projets

1. Régulation transcriptionnelle génétique et épigénétique des gènes de stress abiotiques chez les plantes.

2. Cartographie des traits génétiques dans les cultures avec séquençage de prochaine génération.

Prix et études

Doctorat, Biologie du génome et bioinformatique, Université de Toronto, 2009

BSc.,  Honneurs Biologié, Université de Guelph, 1997

Principales publications

Pour une liste complète de publications, visitez : AAC en ligne

  • Saatian, B., Austin, R.S., Tian, G., Chen, C., Nguyen, V., Kohalmi, S.E., Geelen, D., Cui, Y. Analysis of a novel mutant allele of GSL8 reveals its key roles in cytokinesis and symplastic trafficking in Arabidopsis (2018) BMC Plant Biology, 18 (1), art. no. 295.
  • Duwadi, K., Austin, R.S., Mainali, H.R., Bett, K., Marsolais, F., Dhaubhadel, S. Slow darkening of pinto bean seed coat is associated with significant metabolite and transcript differences related to proanthocyanidin biosynthesis (2018) BMC Genomics, 19 (1), art. no. 260.
  • Chen, C., Li, C., Wang, Y., Renaud, J., Tian, G., Kambhampati, S., Saatian, B., Nguyen, V., Hannoufa, A., Marsolais, F., Yuan, Z.-C., Yu, K., Austin, R.S., Liu, J., Kohalmi, S.E., Wu, K., Huang, S., Cui, Y. Cytosolic acetyl-CoA promotes histone acetylation predominantly at H3K27 in Arabidopsis (2017) Nature Plants, 3 (10), pp. 814-824.
  • Xiao, J., Jin, R., Yu, X., Shen, M., Wagner, J.D., Pai, A., Song, C., Zhuang, M., Klasfeld, S., He, C., Santos, A.M., Helliwell, C., Pruneda-Paz, J.L., Kay, S.A., Lin, X., Cui, S., Garcia, M.F., Clarenz, O., Goodrich, J., Zhang, X., Austin, R.S., Bonasio, R., Wagner, D. Cis and trans determinants of epigenetic silencing by Polycomb repressive complex 2 in Arabidopsis (2017) Nature Genetics, 49 (10), pp. 1546-1552.
  • Dastmalchi, M., Chapman, P., Yu, J., Austin, R.S., Dhaubhadel, S. Transcriptomic evidence for the control of soybean root isoflavonoid content by regulation of overlapping phenylpropanoid pathways (2017) BMC Genomics, 18 (1), art. no. 70.
  • Hossain, M.S., Shrestha, A., Zhong, S., Miri, M., Austin, R.S., Sato, S., Ross, L., Huebert, T., Tromas, A., Torres-Jerez, I., Tang, Y., Udvardi, M., Murray, J.D., Szczyglowski, K. Lotus japonicus NF-YA1 plays an essential role during nodule differentiation and targets members of the SHI/STY gene family (2016) Molecular Plant-Microbe Interactions, 29 (12), pp. 950-964.
  • Austin, R.S., Hiu, S., Waese, J., Ierullo, M., Pasha, A., Wang, T.T., Fan, J., Foong, C., Breit, R., Desveaux, D., Moses, A., Provart, N.J. New BAR tools for mining expression data and exploring Cis-elements in Arabidopsis thaliana (2016) Plant Journal, 88 (3), pp. 490-504.
  • Gao, R., Austin, R.S., Amyot, L., Hannoufa, A. Comparative transcriptome investigation of global gene expression changes caused by miR156 overexpression in Medicago sativa (2016) BMC Genomics, 17 (1), art. no. 658.
  • Elhiti, M., Wang, H., Austin, R.S., Chen, B., Brown, D., Wang, A. Generation of chemically induced mutations using in vitro propagated shoot tip tissues for genetic improvement of fruit trees (2016) Plant Cell, Tissue and Organ Culture, 124 (2), pp. 447-452.
  • Na, R., Yu, D., Chapman, B.P., Zhang, Y., Kuflu, K., Austin, R., Qutob, D., Zhao, J., Wang, Y., Gijzen, M. Genome re-sequencing and functional analysis places the Phytophthora sojae avirulence genes Avr1c and Avr1a in a tandem repeat at a single locus (2014) PLoS ONE, 9 (2), art. no. e89738.
  • Austin, R.S., Chatfield, S.P., Desveaux, D., Guttman, D.S. Next-generation mapping of genetic mutations using bulk population sequencing (2014) Methods in Molecular Biology, 1062, pp. 301-315.
  • Zou, X., Shi, C., Austin, R.S., Merico, D., Munholland, S., Marsolais, F., Navabi, A., Crosby, W.L., Pauls, K.P., Yu, K., Cui, Y. Genome-wide single nucleotide polymorphism and Insertion-Deletion discovery through next-generation sequencing of reduced representation libraries in common bean (2014) Molecular Breeding, 33 (4), pp. 769-778.
  • Austin, R.S., Wu, D., Zhou, S., Brown, D. The root transcriptome for North American ginseng assembled and profiled across seasonal development (2013) BMC Genomics, 14 (1), art. no. 564.
  • Schreiber, K.J., Austin, R.S., Gong, Y., Zhang, J., Fung, P., Wang, P.W., Guttman, D.S., Desveaux, D. Forward chemical genetic screens in Arabidopsis identify genes that influence sensitivity to the phytotoxic compound sulfamethoxazole (2012) BMC Plant Biology, 12, art. no. 226.
  • Liao, D., Pajak, A., Karcz, S.R., Patrick Chapman, B., Sharpe, A.G., Austin, R.S., Datla, R., Dhaubhadel, S., Marsolais, F. Transcripts of sulphur metabolic genes are co-ordinately regulated in developing seeds of common bean lacking phaseolin and major lectins (2012) Journal of Experimental Botany, 63 (17), pp. 6283-6295.
  • Austin, R.S., Vidaurre, D., Stamatiou, G., Breit, R., Provart, N.J., Bonetta, D., Zhang, J., Fung, P., Gong, Y., Wang, P.W., McCourt, P., Guttman, D.S. Next-generation mapping of Arabidopsis genes (2011) Plant Journal, 67 (4), pp. 715-725.
  • Winter, C., Austin, R., Blanvillain-Baufumé, S., Reback, M., Monniaux, M., Wu, M.-F., Sang, Y., Yamaguchi, A., Yamaguchi, N., Parker, J., Parcy, F., Jensen, S., Li, H., Wagner, D. LEAFY Target Genes Reveal Floral Regulatory Logic, cis Motifs, and a Link to Biotic Stimulus Response (2011) Developmental Cell, 20 (4), pp. 430-443.
  • Morris, P.F., Schlosser, L.R., Onasch, K.D., Wittenschlaeger, T., Austin, R., Provart, N. Multiple horizontal gene transfer events and domain fusions have created novel regulatory and metabolic networks in the oomycete genome (2009) PLoS ONE, 4 (7), art. no. e6133.
  • Austin, R.S., Provart, N.J., Cutler, S.R. C-terminal motif prediction in eukaryotic proteomes using comparative genomics and statistical over-representation across protein families (2007) BMC Genomics, 8, art. no. 191.
  • Toufighi, K., Brady, S.M., Austin, R., Ly, E., Provart, N.J. The botany array resource: e-Northerns, expression angling, and promoter analyses (2005) Plant Journal, 43 (1), pp. 153-163.
  • Austin, R., Provart, N.J., Sacadura, N.T., Nugent, K.G., Babu, M., Saville, B.J. A comparative genomic analysis of ESTs from Ustilago maydis (2004) Functional and Integrative Genomics, 4 (4), pp. 207-218.

Affiliations

Professeur auxillaire, Western University

Membre - Société canadienne des biologistes des plantes

Membre - Société américaine des biologistes des plantes

Langue

Anglais