Martin Lessard, PhD

Image Martin LESSARD, PhD
Chercheur scientifique

Contribuer à l'avancement de la recherche en santé animale en examinant des stratégies alimentaires et vaccinales visant à renforcer l’immunité des porcs et à réduire l’utilisation d’antibiotiques dans la production porcine.

Recherche et / ou projets en cours

Le programme de recherche du Dr Lessard contribue à améliorer la santé des porcelets en examinant des stratégies alimentaires et vaccinales visant à renforcer l’immunité des porcs et à réduire l’utilisation d’antibiotiques dans la production porcine. Des concepts complexes d’immunologie, de microbiologie et nutrition sont considérés pour mieux comprendre les interactions hôte-microbiote et le développement du système immunitaire. Il coordonne et collabore à de nombreux projets multidisciplinaires impliquant des institutions nationales et internationales. Les objectifs sectoriels ciblés par les travaux du Dr Lessard sont donc : (1) Accroître la productivité agricole et  (2) Éliminer les menaces contre la chaîne de valeur agricole et agroalimentaire.

Énoncés de recherches/projets

  • Neonatal nutritional interventions with bovine colostrum, and/or vitamin D and copper (Cu) and their programming effects on oxidative status, maturation of the immune system and establishment of intestinal microbial populations in piglets – AAFC and Swine Cluster II

  • Determine the efficiency of a commercial Cheddar cheese to modulate inflammatory status and gut microbiota in pigs fed high fat diet – AAFC and Dairy Cluster II.

  • Understanding gut microbiota and host immune responses to probiotics and bovine colostrum for improving pig gut health – AAC A-Base

  • Bactériothérapie chez le porcelet: preuve de concept. AAC et Programme de subvention « Nouvelle Initiative » du CRIPA

  • Innovative micronutrient strategies for maximizing piglet’s robustness and performance during the pre- and post-weaning periods – AAFC and Swine Cluster III

  • Towards a new feeding approach of neonatal and weanling piglet for optimizing nutritional status, immunity and microbiota and minimizing the use of antibiotics – AAFC and Swine Cluster III.

Activités professionnelles / intérêts

  • Appartenance à des comités de révision d’organismes subventionnaire
  • Supervision d'étudiants gradués
  • Éditeur du journal "Animals"
  • Membre associé du Centre de recherche en infectiologie porcine et avicole
  • Membre régulier de l'Institut sur la nutrition et les aliments fonctionnels (INAF)

Prix et études

Diplôme                       Année              Discipline                                            Université

Baccalauréat                1980                Bio-agronomie                                    Laval, Québec

Maîtrise                        1983                Zootechnie                                          Laval, Québec

Doctorat                       1988                Nutrition et immunologie                     Laval, Québec

Expérience et / ou de travail international

Transfert de travail en France à l’Unité Mixte de Recherches sur le Veau et le Porc, Institut National de Recherche Agronomique.

Principales publications

Pour une liste complète de publications, visitez : AAC en ligne

Publications de revues à comité de lecture

  1. Lessard, M.  and G. J. Brisson.  1987.  Effect of a Lactobacillus fermentation product on growth, immune response and fecal enzyme activity in weaned pigs.  Can. J. Anim. Sci. 67:509-51.
  2. Lessard, M. W. C. Yang, G. S. Elliot, A. H. Rebar, J. F. Van Vleet, N. Deslauriers, G. J. Brisson and R. D. Schultz.  1991.  Cellular immune responses in pigs fed a vitamin E‑ and selenium‑deficient diet.  J. Anim. Sci. 69:1575-1582.
  3. Lessard, M., W. C. Yang, G. S. Elliot, N. Deslauriers, G. J. Brisson, J. F. Van Vleet and R. D. Schultz.  1993.  Suppressive effect of serum from pigs and dogs fed a diet deficient in vitamin E and selenium on lymphocyte proliferation.  Vet. Res. 24:291-303.
  4. Lessard, M., M. Dupuis. 1994.  Differential modulation of chicken lymphocyte blastogenesis and cytotoxic activity of natural killer cells in vitro by retinol, retinoic acid and beta-carotene. Nutrition Res. 14:1201-1217.
  5. Rotter, B. A., B. K. Thompson, M. Lessard, H. L. Trenholm and H. Tryphonas.  1994. Influence of low-level exposure to Fusarium mycotoxins on selected immunological and hematological parameters in young swine.  Fundam. Appl. Toxicol. 23:117-124.
  6. Lessard, M., D. L. Hutchings, J. L. Spencer. 1995.  Cell-mediated and humoral immune responses in chickens infected with Salmonella typhimurium. Avian Dis. 39:230-238.
  7. Rotter, B. A., B. K. Thompson and M. Lessard. 1995.  Effects of deoxynilavenol-contaminated diet on selected blood parameters in growing swine.  Can. J. Anim. Sci. 75:297-302.
  8. Lessard, M., D. L. Hutchings, J. L. Spencer, H. S. Lillehoj, and J. S. Gavora.  1996.  Influence of Marek’s disease virus strain AC-1 on cellular immunity in birds carrying endogenous viral genes.  Avian Dis.40:645-653.
  9. Lessard, M., D. L. Hutchings, and N. A. Cave.  1997.  Cell-mediated and humoral immune responses in meat type chickens maintained on diets containing different leves of vitamin A.  Poult. Sci. (76:1368-1378).
  10. Lessard, M., S. He, B. Benkel.  1998.  Technical note:  A quantitative competitive reverse transcription-polymerase chain reaction (qcRT-PCR) technique to measure porcine interferon-gamma.  J. Anim. Sci. 76:2155-2161
  11. Taylor, A. A., D. M.Weary, M. Lessard, and L. Braithwaite.  2001.  Behavioural responses of piglets to castration: the effect of piglet age.  Applied Animal Behavior Science 73: 35-43.
  12. Chabot, S., H.-L. Yu, L. De Léséleuc, D. Cloutier, M.-R. Van Calsteren, M. Lessard, D. Roy, M. Lacroix, and D. Oth. 2001. Exopolysaccharides from Lactobacillus rhamnosus RW-9595M stimulate TNF, IL-6 and IL-12 in Human and Mouse cultured immunocompetent cells, and IFN-g in Mouse splenocytes. Lait 81 : 683-697.
  13. Vallée, M., Guay, F., Beaudry, D., Matte, J.J., Blouin, R., Laforest, J.P., Lessard, M. and Palin, M.-F. 2002. Effects of Breed, parity, and Folic Acid Supplement on the Expression of Folate Metabolism Genes in Endometrial and Embryonic Tissues from Sows in early pregnancy. Biol. Reprod. 67:1259-1267.
  14. Lessard, M. A. A. Taylor, L. Braithwaite  and D. M.Weary.  2002.  Humoral and cellular immunity responses of piglets after castration at different ages.  Can. J. Anim. Sci. 82:519-526.
  15. Chartrand, R., J. J. Matte, M. Lessard, P. Y. Chouinard, A. Giguère, and J. P. Laforest.  2003.  Effect of dietary polyunsaturated fatty acids on systemic and utrauterine synthesis of prostaglandins during early pregnancy in gilts.  J. Anim. Sci. 81:726-734.
  16. Lessard, M., N. Gagnon, H. Petit. 2003. Immune response of postpartum dairy cows fed flaxseed. J. Dairy Sci. 86:2647-2657.
  17. Seyer, K.; Lessard, M.; Piette, G.; Lacroix, M.; Saucier, L.  2003.  Use of DNAK as a biomarker to assess the effeciency of heat treatment and the stress response in Escherichia coli.  Appl. Environm. Microbiol. 69: 3231-3237.
  18. Lessard, M., M.Lépine, J. J. Matte, J. P. Laforest. 2003. Uterine immune reaction and reproductive performance of sows inseminated with extended semen and infused with pooled whole dead semen. J. Anim. Sci. 81: 2818-2825.
  19. Chabot, V., R. D. Lambert, J.-P. Laforest, S. St-Jacques, J. J. Matte, F. Guay , M.-F. Palin, and M. Lessard. 2003. Effect of Estrous Cycle and Early Pregnancy on Uterine Production and Expression of Immune Regulatory Factors in Gilts. Anim Reprod. Sci 81:137–149.
  20. Lessard, M., N. Gagnon, D. Godson and H. V. Petit. 2004. Immune Response of Dairy Cows Fed Diets Enriched in n-3 or n-6 Polyunsaturated Fatty Acids During the Transition Period. J. Dairy Sci. 87:2197–2210.
  21. Lessard, M., Dupuis, M. and Farmer C. 2005. Effects of prolactin inhibition during late gestation on the immunity of gilts and foetuses. Can. J. Anim. Sci. 85: 335-343.
  22. Doepel, L., N. Gagnon, M. Lessard, G. E. Lobley, J. F. Bernier, P. Dubreuil, and H. Lapierre. 2006. Effect of Glutamine Supplementation on Immune Response and Milk Production in Dairy Cows. J. Dairy Sci. 89: 3107-3121.
  23. Gagnon, N., G. Talbot, P. Ward, D. Roy, M Dupuis, E. Farnworth, T. Tompskin, and M. Lessard. 2007. Evaluation of bacterial diversity in the gut of piglets supplemented with probiotics using ribosomal intergenic spacer analysis. Can. J. Anim.Sci. 87:207-219.
  24. Lessard, M., Dupuis, M., Gagnon, N., Nadeau, É., Matte, J.J., Goulet, J., et Fairbrother, J.M. 2009.  Administration of Pediococcus acidilatici or Saccharomyces cerevisiae boulardii modulates development of porcine mucosal immunity and reduces intestinal bacterial translocation after Escherichia coli challenge. J. Anim. Sci. 87 : 922-934 - DOI: 10.2527/jas.2008-0919.
  25. Lessard, M., G. Boudry, B. Sève B., I. P. Oswald and J. P. Lallès. 2009. Intestinal physiology and peptidase activity in male pigs are modulated by consumption of corn culture extracts containing fumonisins. J. Nutr. 139 : 1303-1307.
  26. Lallès, J. P., Lessard, M. and G. Boudry. 2009. Intestinal Barrier Function is Modulated by Short-term Exposure to Fumonisin B1 in Ussing Chambers. Veterinary Research Communications 33:1039-1043.
  27. Alain, K., N. Karrow, C. Thibault, J. St-Pierre, M. Lessard, and N. Bissonnette. 2009. Osteopontin: An early innate immune makers of escherichia coli mastitis harbors genetic polymorphisms with possible links with resistance to mastitis. BMC Genomics 10: 444.
  28. Torrey, S., N. Devillers, M. Lessard, C. Farmer, and T. Widowski. 2009. Effect of age on the behavioral and physiological responses of piglets to tail docking and ear notching. J. Anim. Sci. 87: 1778-1786.  
  29. Lallès, J. P., M. Lessard, I. P. Oswald, and J. C. David. 2010. Consumption of fumonisin b1 for 9 days induces stress proteins along the gastrointestinal tract of pigs. Toxicon 55:244-249.
  30. Farmer, C., A. Giguère, and M. Lessard. 2010. Dietary supplementation with different forms of flax in late-gestation and lactation: effects on sow and litter performances, endocrinology and immune response. J. Anim. Sci. 88: 225-237.
  31. Daudelin J. F., M. Lessard, F. Beaudoin, É. Nadeau, N. Bissonnette, Y. Boutin, J.-P. Brousseau, K. Lauzon, J. M. Fairbrother. 2011. Administration of Pediococcus acidilactici and Saccharomyces cerevisiae boulardii influences enterotoxigenic Escherichia coli F4 attachment and intestinal cytokine expression in weaned pigs. Vet Res. 42:69-80.
  32. Matte, J. J., N. LeFloc'h, Y. Primot, and M. Lessard. 2011. Interaction between dietary tryptophan and pyridoxine on tryptophan metabolism, immune responses and growth performance in post-weaning pigs. Animal Feed Science and Technology 170: 256-264.
  33. Assaad, E., L. Blemur, M. Lessard and M. A. Mateescu. 2011. Polyelectrolyte complex of carboxymethyl starch and chitosan as protein carrier: Oral administration of ovalbumin. Journal of Biomaterials Science, Polymer Edition 23:13, 1713-1728. 
  34. Roblet, C., J. Amiot, C. Lavigne, A. Marette, M. Lessard, J. Jean, C. Ramassamy, C. Moresoli, and L. Bazinet. 2012. Screening of in vitro bioactivities of a soy protein hydrolysate separated by hollow fiber and spiral-wound ultrafiltration membranes. Food Research International 46: 237-249.
  35. Lessard, M., F. Beaudoin, M. Ménard, M.-P. Lachance, J. P. Laforest and C. Farmer. 2012. Impact of a long photoperiod during lactation on immune status of piglets. J. Anim. Sci. 90:1-9.
  36. Roques, E., A. Girard, M.-C. St-Louis, B. Massie, C.  A. Gagnon, M. Lessard and D. Archambault. 2013. Immunogenic and protective properties of  codon-optimized GP5 and M structural proteins of porcine reproductive and  respiratory syndrome virus expressed from replicating but nondisseminating  adenovectors. Vet. Res. 44: 17-30.
  37. Bovey, K.E., T.M. Widowski, C.E. Dewey, N. Devillers, C. Farmer, M. Lessard and S. Torrey. 2014. The effect of birth weight and age at tail docking and ear notching on the behavioral and physiological responses of piglets. J. Anim. Sci. 92:1718-1727.
  38. Dudemaine, P. L., M. Lessard, G. Fecteau, O. Labrecque, J.-P. Roy and N. Bissonnette. 2014. Increased blood-circulating IFN γ, IL 17, and osteopontin levels in bovine paratuberculosis. J. Dairy Sci  97 (6) :3382-3393.
  39. Champagne, C. P., Raymond, Y.,  Pouliot, Y.,  Gauthier, S. F. and Lessard, M. 2014. Effect of bovine colostrum, cheese whey and spray dried porcine plasma on the growth of probiotic bacteria and Escherichia coli. Canadian Journal of Microbiology 60(5): 287-295.
  40. Blais, M., Y. Pouliot, S. Gauthier, Y. Boutin and M. Lessard. 2014. A gene expression program induced by bovine colostrum whey promotes growth and wound healing processes in intestinal epithelial cells. J. Nutr. Sci. 3, e57, Page 1-10 (doi:10.1017/jns.2014.56).
  41. Blais, M., M. Fortier, Y. Pouliot, S. Gauthier, Y. Boutin, C. Asselin and M. Lessard. 2015.  2015. Colostrum whey down-regulates the expression of early and late inflammatory response genes induced by Escherichia coli and Salmonella enterica Typhimurium components in intestinal epithelial cells. Br. J. Nutr. 113: 200-211. (DOI:10.1017/S0007114514003481).
  42. Audet, I., C. L. Girard, M. Lessard, L. Lo Verso, F. Beaudoin and J. J. Matte. 2015. Homocysteine metabolism, growth performance, and immune responses in suckling and weanling piglets. J. Anim Sci. 2015; 93:147-157 doi:10.2527/jas.2014-7872.
  43. Lessard, M., C. Savard, K. Deschene, K. Lauzon, V. A. Pinilla, C. A. Gagnon, J. Lapointe, F. Guay, and Y. Chorfi. 2015. Impact of deoxynivalenol (DON) contaminated feed on intestinal integrity and immune response in swine. Food Chem. Toxicol. 80: 7-16.
  44. Le Thanh, B. V., M. Lessard, Y. Chorfi, and F. Guay. 2015. The efficacy of anti-mycotoxin feed additives in preventing the adverse effects of wheat naturally contaminated with fusarium mycotoxins on performance, intestinal barrier function and nutrient digestibility and retention in weanling pigs. Can. J. Anim. Sci. 95: 197-209 (doi:10.4141/CJAS-2014-4126).
  45. Roques, E.  M. Lessard, and D. Archambault. 2015. The Cholera Toxin B Subunit (CTB) Fused to the Porcine Arterivirus Matrix M and GP5 Envelope Proteins Fails to Enhance the GP5-Specific Antibody Response in Pigs Immunized with Adenovectors. Mol. Biotechnol. DOI 10.1007/s12033-015-9861-6.
  46. Brousseau, J. P., G. Talbot, F. Beaudoin, K. Lauzon, D. Roy, and M. Lessard*††. 2015.  Effects of Pediococcus acidilactici and Saccharomyces cerevisiae subsp. boulardii on fecal and intestinal microbiota of nursing and weanling piglets. J. anim. Sci. J. Anim. Sci. 2015.93:5313–5326, doi:10.2527/jas2015-9190.
  47. Topp, E., Irwin, R., McAllister, T., Lessard, M., Joensuu, J. J., Kolotilin, I., Conrad, U., Stöger, E., Mor, T., Warzecha, H., Hall, J. C., McLean, M. D., Cox, E., Devriendt, B., Potter, A., Depicker, A.,Virdi, V., Holbrook, L., Doshi, K., Dussault, M., Friendship, R., Yarosh, O., Yoo, H. S., MacDonald, J. and   Menassa, R. 2015. The case for plant-made veterinary immunotherapeutics. Biotechnology Advances, dx.doi.org/10.1016/j.biotechadv.2016.02.007.
  48. Le Thanh, B. V., M. Lessard, Y. Chorfi, and F. Guay. 2015. Short communication: Antioxidant capacity in the intestinal mucosa of weanling piglets fed diets containing Fusarium mycotoxins and the efficacy of commercial supplements sold as detoxifiers. Can. J. Anim. Sci. 95: 569-575 (doi:10.4141/CJAS-2015-037).
  49. Le Thanh, B. V., M. Lemay, A. Bastien, J. Lapointe, M. Lessard, Y. Chorfi, and F. Guay 2016. The potential effects of antioxidant feed additives in mitigating the adverse effects of corn naturally contaminated with Fusarium mycotoxins on antioxidant systems in the intestinal mucosa, plasma and liver in weaned pigs. Mycotoxin Research  (Ms. No. MYRE-D-16-00012R1; accepted for publication).
  50. Plante, S., G. Talbot,  M. Lessard et F. Guay. 2016.  Développement d'un programme alimentaire pour porcelet sevré en production biologique. Journées Recherche Porcine 48 : 61-66.
  51. Bissonnette, N., Jiang, X.R., Matte, J.J., Guay, F., Talbot, G., Bontempo, V., Gong, J., Wang, Q., Lessard, M., 2016. Effect of a post-weaning diet supplemented with functional feed additives on ileal transcriptome activity and serum cytokines in piglets challenged with lipopolysaccharide. Vet. Immunol. Immunopathol. 182 : 136-149.
  52. Farmer, C., M. Lessard, C. H. Knight, and H. Quesnel. 2017. Oxytocin injections in the postpartal period affect mammary tight junctions in sows. J. Anim. Sci. 95(8):3532-3539. doi: 10.2527/jas.2017.1700.
  53. Morissette, B., G. Talbot, C. Beaulieu and M. Lessard. 2017. Growth performance of piglets during the first two weeks of lactation affects the development of the intestinal microbiota. J. Anim. Physiol. Anim. Nutr. 102, 525–532. doi: 10.1111/jpn.12784.
  54. Lo Verso, L.; M. Lessard, G. Talbot, B. Fernandez, I. Fliss. 2018. Isolation and selection of potential probiotic bacteria from the pig gastrointestinal tract. Probiotics & Antimicro. Prot. 10: 299-312. https://doi.org/10.1007/s12602-017-9309-3.
  55. Lapointe, J., Ketilim-Novais, A., Bergeron, N.,  Roy, C., Lessard, M., Matte, J.J. 2017. Caractérisation de marqueurs du métabolisme énergétique mitochondrial et du stress oxydatif chez des porcelets de faibles poids et de poids normaux en période péri-sevrage. Journées Recherche Porcine 50 : 195-200.
  56. Fomenky, B. E., J. Chiquette, M. Lessard, N. Bissonnette, G. Talbot, Y. P. Chouinard, and E. M. Ibeagha-Awemu. 2018. Saccharomyces cerevisiae var. boulardii CNCM I-1079 and Lactobacillus acidophilus BT1386 influence innate immune response and serum levels of acute-phase proteins during weaning in Holstein calves. Can. J. Anim. Sci. 98 :578-590. doi: 10.1139/cjas-2017-0120.
  57. Lessard, M., M. Blais, F. Beaudoin, K. Deschene, L. Lo Verso, N. Bissonnette, K. Lauzon and F. Guay. 2018. Piglet weight gain during the first two weeks of lactation influence the immune system development. Vet. Immunol. Immunopathol. 206: 25-34.
  58. Galiot, L., I. Audet, B. Ouattara, N, Bissonnette, G. Talbot, J. Lapointe, L. Lo Verso, M. Lessard, J. J. Matte et F. Guay. 2019. Effet d’une supplémentation en cuivre, vitamines A et D et colostrum bovin sur les performances de croissance et le microbiome du porcelet pendant la lactation. Journées Rech. Porcine en France. 51:61-66.
  59. Novais, A. K., Y. Martel-Kennes, C. Roy, K. Deschene, S. Beaulieu, N. Bergeron, J. P. Laforest, M. Lessard, J. J. Matte, and J. Lapointe. 2019. Tissue-specific profiling reveals modulation of cellular and mitochondrial oxidative stress in normal- and low-birthweight piglets throughout the peri-weaning period. Animal:1-11. doi: 10.1017/S1751731119002829

Documents soumis à un comité de lecture

60. Lo Verso, L., J. J. Matte, J. Lapointe, G. Talbot, N. Bissonnette, F. Guay, M. Lessard. 2020. Impact of birth weight and neonatal nutritional interventions with micronutrients and bovine colostrum on the development of piglet immune response during the peri-weaning period. Veterinary Immunology and Immunopathology, VETIMM_2019-227-R1

61. Perazza, L. R., N. Daniel, M.-J. Dubois, G. Pilon; T. V. Varin, M. Blais, J. L. Martinez, M. Bouchard; C. Asselin, M. Lessard, Y. Pouliot, D. Roy and A. Marette. 2020. Distinct effects of milk-derived and fermented dairy proteins on gut microbiota and cardiometabolic markers in diet-induced obese mice.  Journal of Nutrition (MS Number: JN-2020-0239).

62. Lauridsen, C., J. J. Matte, M. Lessard, P. Celi, G. Litta. 2020. Role of vitamins for gastro-intestinal functionality and health of pigs. Animal Feed Science and Technology (MS Number: ANIFEE_2019_1609).

63. Galiot, L. et al. 2020. Effects of sources and routes of administration of vitamins A, D and copper on postnatal status of these micronutrients in piglets. Journal of Trace Elements in Medicine and Biology

64. Lo Verso, L., G. Talbot, B. Morissette, F. Guay, J. J. Matte, C. Farmer, J. Gong, Q. Wang, N. Bissonnette, C. Beaulieu and Martin Lessard. 2020. The Combination of nutraceuticals and functional feeds as additives modulates gut microbiota and blood markers associated with immune response and health in weanling piglets. J. Anim. Sci.

 

Rapports techniques et procédures (2013-2019)

2016

  • Topp, E., Irwin, R., McAllister, T.A., Lessard, M., Joensuu, J.J., Kolotilin, I., Conrad, U., Stöger, E., Mor, T., Warzecha, H., Hall, J.C., McLean, M.D, Cox, E., Devriendt, B., Potter, A., Depicker, A., Virdi, V., Holbrook, L., Doshi, K., Dussault, M., Friendship, R.M., Yarosh, O., Yoo, H.S., MacDonald, J.D., and Menassa, R. (2016). "The case for plant-made veterinary immunotherapeutics.", Biotechnology Advances. doi : 10.1016/j.biotechadv.2016.02.007

 

2015

 

2014

 

2013

 

2012

 

2011

 

2009

 

Other science related publications

 

2016

  • Lo Verso, L., Matte, J.J., Talbot, G., Bissonnette, N., Lapointe, J., Gagnon, N., Ouattara, B., Guay, F., and Lessard, M. (2016). "Effects of different sources and routes of administration of copper and vitamins A and D on gut volatile fatty acids and gene expression involved in regulation of innate and acquired immunity in piglets.", Journal of Animal Science, 94(Supp. 2). (Abstract)
  • Matte, J.J., Audet, I., Ouattara, B., Bissonnette, N., and Lessard, M. (2016). "Sources and routes of administration of copper and vitamins A and D on metabolic status of these micronutrients in suckling piglets.", Journal of Animal Science, 94(Supp. 2), pp. 116. (Abstract)
  • Talbot, G., Lessard, M., Yergeau, E., Gagnon, N., Lo Verso, L., Lapointe, J., Bissonnette, N., Bueno Dalto, D., Ouattara, B., Guay, F., and Matte, J.J. (2016). "Effects of different sources and routes of administration of copper and vitamins A and D on piglets gut microbiota.", Journal of Animal Science, 94(Supp. 2). (Abstract)
  • Talbot, G., Lessard, M., Yergeau, E., Gagnon, N., Lo Verso, L., Lapointe, J., Bissonnette, N., Bueno Dalto, D., Ouattara, B., Guay, F., and Matte, J.J. (2016). "Microbiota of the small intestine of piglets affected by perinatal administration of copper and vitamins A and D.", 18th International Conference on Microbiota Buenos Engineering, Buenos Aires, Argentina, 27-28 October, 2016.

 

2015

  • Bissonnette, N., Jiang, X-R., Matte, J.J., Talbot, G., Guay, F., Gong, J., Wang, Q., Bontempo, V., and Lessard, M. (2015). "Effect of a post-weanling diet supplemented with gut health-enhancing feed additives on ileum transcriptome activity and serum cytokines in piglets challenged with lipopolysaccharides (LPS)", ADSA-ASAS JAM (Joint Annual Meeting) 2015, Orlando, Florida, USA, July 12-16, 2015, 2-15, Poster Session.
  • Fomenky, B., Beaudoin, F., Chiquette, J., Talbot, G., Bissonnette, N., Chouinard, P.Y., Lessard, M., and Ibeagha-Awemu, E.M. (2015). "Amélioration du développement immunitaire chez les veaux laitiers par les probiotiques.", Symposium sur les bovins laitiers 2015, Drummondville, QC, Canada, Octobre 29, 2015.
  • Ibeagha-Awemu, E.M., Beaudoin, F., Chiquette, J., Talbot, G., Bissonnette, N., and Lessard, M. (2015). "Probiotics administration enhances calves’ lymphoproliferation responses to vaccination during the early weeks of growth.", 2015 Conference of the Canadian Society of Animal Science and the Canadian Meat Council, Ottawa, Canada, May 6-8, 2015.
  • Lessard, M. (2015). "La santé intestinale : Interactions entre l’alimentation, le microbiote et le système immunitaire.", Intégrer des ingrédients novateurs en alimentation porcine et avicole, Centre Québécois de valorisation des biotechnologies et Centre de développement du porc du Québec.

 

2014

  • Atia, A., Lessard, M., Beyssac, E., Garrait, G., Gomaa, A., Fliss, I., and Subirade, M. (2014). "Les probiotiques et l’alimentation porcine.", 6ième Colloque international francophone de microbiologie animale, École nationale vétérinaire de Toulouse, Toulouse, France, May 15-16, 2014.
  • Audet, I., Girard, C.L., Lessard, M., Lo Verso, L., and Matte, J.J. (2014). "Homocysteinemia, growth performance, and immune responses in suckling and weanling piglets.", Journal of Animal Science, 92(E-Suppl.2), pp. 219. (Abstract)
  • Bissonnette, N., Dudemaine, P.-L., Lessard, M., Labrecque, O., Roy, J.-P., and Fecteau, G. (2014). "Increased blood-circulating interferon gamma, interleukin 17 and osteopontin levels in bovine paratuberculosis.", 12th International Colloquium on Paratuberculosis, Parma, Italy, Abstract ID 3. (Abstract)
  • Le Thanh, B.V., Lessard, M., Chorfi, Y., and Guay, F. (2014). "Antioxidant activity of intestinal mucosa in piglets fed deoxynivalenol naturally contaminated diet.", ADSA-ASAS 2014 Joint Annual Meeting, Kansas City, MO, USA, July 20-24, 2014, Also published on J. Anim. Sci. 92 (E-Suppl. 2): 686.
  • Lessard, M., Bergeron, N., Deschêne, K., Matte, J.J., Guay, F., Bissonnette, N., Talbot, B.G., Gong, J., Wang, Q., Quessy, S., and Letellier, A. (2014). "Intestinal gene expression involved in innate and acquired immune responses of pigs is affected by Salmonella infection and diets supplemented with gut health-enhancing feed additives.", 23rd International Pig Veterinary Society Congress, Cancun, México, June 8-11, 2014, Abstract A1387. (Poster)
  • Lessard, M., Bergeron, N., Deschêne, K., Matte, J.J., Guay, F., Bissonnette, N., Talbot, B.G., Quessy, S., and Letellier, A. (2014). "Influence of Salmonella infection and diets supplemented with gut health-enhancing feed additives on expression of intestinal genes involved in immune response of pigs.", 7ième Symposium du CRIPA, Hyacinthe, Québec, Canada, 3-4 juin 2014. (Poster)
  • Lessard, M., Deschêne, K., Savard, C., Gagnon, A.-È., Lapointe, J., Pinilla, V.A., Guay, F., and Chorfi, Y. (2014). "Effect of deoxynivalenol (DON) ingestion on expression of genes involved in intestinal barrier and immune functions.", 7ième Symposium du CRIPA, Hyacinthe, Québec, Canada, 3-4 juin 2014, Présentation orale.
  • Lessard, M., Deschêne, K., Savard, C., Lapointe, J., Guay, F., and Chorfi, Y. (2014). "Effect of deoxynivalenol (DON) ingestion on expression of genes involved in intestinal integrity and immune response.", 2014 ADSA-ASAS Midwest Meeting, Iowa Events Center, Des Moines, Iowa, USA, March 17-19, 2014, # 163; Oral Présentation. (Abstract)
  • Morisette, B., Lessard, M., Yergeau, E., Lapointe, J., Guay, F., Bissonnette, N., Matte, J.J., Letellier, A., Quessy, S., Bergeron, N., Beaulieu, C., and Talbot, G. (2014). "Influence of Feed Additives as an Alternative to Antibiotics on Gut Microbiota of Weaned Piglets Infected with Salmonella Typhimurium.", 114th General Meeting of the American Society for Microbiology, Boston, Massachusetts, USA, May 17-20, 2014.
  • Morissette, B., Lessard, M., Yergeau, E., Lapointe, J., Guay, F., Bissonnette, N., Matte, J.J., Letellier, A., Quessy, S., Bergeron, N., and Talbot, B.G. (2014). "Influence of Feed Additives as an Alternative to Antibiotics on Gut Microbiota of Weaned Piglets Infected with Salmonella Typhimurium.", 7ième Symposium du CRIPA, Hyacinthe, Québec, Canada, 3-4 juin 2014. (Poster)

 

2013

  • Abdelbasset, A., Lo Verso, L., Fliss, I., Lessard, M., Talbot, G., and Subirade, M. (2013). "Protection of probiotic bacteria in a symbiotic matrix.", 6th Symposium of Swine and Poultry Infectious Diseases Research Center. Congrès de l’ACFAS Colloque 227 – Le microbiote animal : une question d’équilibre., Université Laval, Québec, QC, Canada, May 8-9, 2013. (Poster)
  • Atia, A., Fliss, I., Lessard, M., and Subirade, M. (2013). "Une matrice synbiotique pour la protection des probiotiques.", Symposium PROBIO 2013 "Probiotiques au-delà de la santé intestinale", Montréal, Québec, Canada, October 30-31, 2013.
  • Audet, I., Girard, C.L., Lessard, M., and Matte, J.J. (2013). "Métabolisme de l’homocystéine et performacnes de croissance chez le porcelet pendant l’allaitement et après le sevrage.", Journées d’Information scientifique en productions animales, Québec, Canada, pp. 28-29.
  • Bergeron, N., Lessard, M., Quessy, S., and Letellier, A. (2013). "Evaluation of feeding strategies to reduce Salmonella infection in piglets.", 12ème réunion annuelle du Réseau Canadien des Travailleurs des Laboratoires de Santé Animale (RCTLSA)/ Canadian Animal Health Laboratorians Network (CAHLN), St-Hyacinthe, Québec, Canada, May 27-29, 2013.
  • Bergeron, N., Lessard, M., Quessy, S., and Letellier, A. (2013). "Evaluation of the impact of functional food on the course of Salmonella infection in piglets.", SafePork, 9th International Symposium on the Epidemiology and Control of Foodborne Pathogens in Pork, Portland, Maine, USA, September 9-12, 2013.
  • Bergeron, N., Lessard, M., Quessy, S., and Letellier, A. (2013). "Feeding strategies to reduce Salmonella infection in piglets.", 6th Symposium of Swine and Poultry Infectious Diseases Research Center. Congrès de l’ACFAS Colloque 227 – Le microbiote animal : une question d’équilibre., Université Laval, Québec, QC, Canada, May 8-9, 2013.
  • Blais, M., Fortier, M.-È., Pouliot, Y., Gauthier, S.F., Boutin, B., and Lessard, M. (2013). "Decaseinated Colostrum Mediates Beneficial Effects On Cell Proliferation, Wound Healing And Inflammatory Response In Porcine Intestinal Epithelial Cells IPEC J2.", 7th Annual meeting of the International Society of Nutrigenetics and Nutrigenomics, October 5-8, 2013, Also published on Canada, J. Nutrigenet. Nutrigenomics 6:207.
  • Deschêne, K., Beaudoin, F., Lauzon, K., Cantin, D., and Lessard, M. (2013). "Expression of Intestinal Immune Genes in Nursing Piglets Is Modulated by Piglet Weight at Birth and their Growth in the First Week of Live.", 7th Annual meeting of the International Society of Nutrigenetics and Nutrigenomics, October 5-8, 2013, Also published on J. Nutrigenet. Nutrigenomics 6:218.
  • Dudemaine, P.-L., Fecteau, G., Lessard, M., Côté, G., Labrecque, O., Buczinski, S., Doré, E., Roy, J.-P., and Bissonnette, N. (2013). "Altered immune response in bovine paratuberculosis.", CSAS-CMSA Joint Annual Meeting, Banff Park Lodge Resort Hotel and Conference Centre, Banff, AB, Canada, June 18-20, 2013, # P05 page 26. (Abstract)
  • Lessard, M. (2013). "Mycotoxins and the Immune System.", Swine Innovation Porc, 1(15).
  • Lo Verso, L., Lessard, M., Talbot, G., Subirade, M., and Fliss, I. (2013). "Isolation and antibacterial activity of potential probiotic bacteria from pig gastrointestinal tract.", 6th Symposium of Swine and Poultry Infectious Diseases Research Center. Congrès de l’ACFAS Colloque 227 – Le microbiote animal : une question d’équilibre., Université Laval, Québec, QC, Canada, May 8-9, 2013, pp. 45. (Poster)
  • Morissette, B., Lessard, M., Guay, F., Matte, J.J., Gong, J., Wang, Q., Beaulieu, C., and Talbot, G. (2013). "Prebiotics, probiotic, nutraceuticals and functional food as feed additives that modulate the gut microbiota of weanling piglets challenged with E. coli lipopolysaccharides.", 63rd Annual Conference of the Canadian Society of Microbiologists, Carleton University, Ottawa, ON, Canada, June 17-20, 2013, Abstract AE56. (Abstract)
  • Talbot, G. and Lessard, M. (2013). "Influence of growth rate, probiotics, nutraceuticals and functional food on intestinal microbiota of suckling and weanling piglets.", 6th Symposium of Swine and Poultry Infectious Diseases Research Center. Congrès de l’ACFAS Colloque 227 – Le microbiote animal : une question d’équilibre., Université Laval, Québec, QC, Canada, May 8-9, 2013.

 

2012

  • Lessard, M. (2012). "Development of novel feeding strategies aiming to improve gut development, defence functions, health and performance of piglets.", Swine Cluster CA members seminar. (Presentation)
  • Lessard, M., Deschêne, K., Savard, C., and Chorfi, Y. (2012). "Effects of DON on porcine intestinal immunity.", Symposium sur les mycotoxines, AQINAC, ANAC et partenaires, Brossard, QC, Canada, December 11, 2012. (Presentation)
  • Morissette, B., Lessard, M., and Talbot, G. (2012). "Is there a link between piglet’s weight gain and its intestinal bacteria?", 2ème symposium du Centre de Recherche et de Développement sur le Bovin Laitier et le Porc / 2nd Annual DSRDC/ CRDBLP Symposium on Animal Production, Sherbrooke, QC, Canada, November 28, 2012.
  • Talbot, G., Morissette, B., and Lessard, M. (2012). "The impact of piglet weight gain on the intestinal microbiota during lactation.", Canadian Society of Microbiologists (CSM) 62nd Annual Conference / Conférence annuelle de la Société Canadienne des Microbiologistes (SCM), Vancouver, BC, Canada, June 20-23, 2012, Abstract II057. (Poster)

 

2011

  • Blais, M., Chambers, J.R., Beaudoin, F., Gauthier, S.F., Pouliot, Y., and Lessard, M. (2011). "Regulation of inflammatory genes by milk fractions in human and swine intestinal epithelial cells.", 4e symposium du Centre de Recherche en Infectiologie Porcine (CRIP), Université de Montréal, Saint-Hyacinthe, QC, Canada, Page 18. (Presentation)
  • Brousseau, J.P., Beaudoin, F., Lauzon, K., Talbot, G., Roy, D., and Lessard, M. (2011). "Effets de Pediococcus acidilactici et Saccharomyces cerevisiae boulardii sur le microbiote de l’iléon et du côlon chez le porcelet sevré.", 4e Symposium Annuel du Centre de Recherche en Infectiologie Porcine (CRIP), Université de Montréal, Saint-Hyacinthe, QC, Canada, May 30-31, 2011. (Abstract)
  • Chambers, J.R., Blais, M., Beaudoin, F., Gauthier, S.F., Pouliot, Y., and Lessard, M. (2011). "Effet du sérocolostrum sur l’expression de gènes de réponse inflammatoire dans les cellules épithéliales intestinales porcines IPEC J2 et les cellules de carcinome de côlon humain Caco-2/15.", XVII colloque annuel d'immuno-inflammation, Eastman, QC, Canada, June 17, 2011. (Presentation)
  • Michaud, N., Gauthier, S.F., Robitaille, G., Pouliot, Y., Tremblay, É., Beaulieu, J.-F., and Lessard, M. (2011). "Modulation de la réaction inflammatoire intestinale par des sous-produits du lait.", Colloque bisannuel du STELA la recherche laitière 2011, Hôtel Palace Royal, Québec City, QC, Canada, May 30-31, 2011.

 

2010

  • Bovey, K., Devillers, N., Lessard, M., Farmer, C., Dewey, C., Widowski, T.M., and Torrey, S. (2010). "The effect of birth weight and age on the behavioural and physiological responses of piglets to tail docking and ear notching.", 44th Congress of the International Society for Applied Ethology, University of Agricultural Sciences, Uppsala, Sweden, August 4-7, 2010, pp. 34.

 

2009

  • Alain, K., Karrow, N.A., Thibault, C., Lessard, M., and Bissonnette, N. (2009). "Development of a multiplex-PCR detection assay for simultaneous identification of the major pathogens causing mastitis in dairy milk.", Journal of Animal Science, 87(E-Suppl. 2), pp. 199-200 (#T6). (Abstract)
  • Alain, K., Karrow, N.A., Thibault, C., Lessard, M., and Bissonnette, N. (2009). "Innate immune responses in dairy cows and study of promising candidate: osteopontin.", Journal of Animal Science, 87(E-Suppl. 2), pp. 198-199 (#T3). (Abstract)
  • Beaudoin, F., Farmer, C., St-Pierre, G., Lachance, M.-P., and Lessard, M. (2009). "Influence of prolonged photoperiod on immune status of piglets.", 3rd European Veterinary Immunology Workshop (EVIW) Satellite meeting of the 2nd European Congress of Immunology (ECI 2009), Berlin, Germany, September 10-13, 2009, pp. 57.
  • Farmer, C., Giguère, A., Lessard, M., and Petit, H.V. (2009). "Feeding flax to late-pregnant and lactating sows: Effects on fatty acid profiles, hormones and performances of sows and their litters.", Journal of Animal Science, 87(Suppl. 2), pp. 64. (Abstract)
  • Lessard, M., Petit, H.V., Giguère, A., and Farmer, C. (2009). "Feeding flax to late-pregnant and lactating sows: Effects on sow immunity and antibody transfer to their piglets.", Journal of Animal Science, 87(Suppl. 2), pp. 62-63. (Abstract)

Affiliations

  • Professeur associé, Département des sciences animales, Université Laval

  • Professeur associé, Département de pathologie et de microbiologie, Faculté de médecine vétérinaire, Université de Montréal

  • Professeur associé, Département de biologie, Université de Sherbrooke

  • Membre régulier de l'Institut sur la nutrition et les aliments fonctionnels (INAF), Université Laval,

  • Membre associé du Centre de recherche en infectiologie porcine et avicole (CRIPA), Université de Montréal, Directeur de l’axe 3 « Prophylaxie anti-infectieuse : vaccins et autres solutions alternatives à l’utilisation des antibiotiques »

Langue

Anglais
Français