G. Douglas Inglis

Chercheur

Microbiologie entérique et santé intestinale

Recherche et / ou projets en cours

  • Taboada EN (CP), Inglis GD (CP), Carrillo C, Wong A, Finley R, Boras V, Chui L. Genome Alberta (Alberta Applied Agricultural Genomics Program). Projet : Génomique comparative des souches de Campylobacter courantes dans la production de volaille au Canada qui sont associées à des maladies humaines : identification de biomarqueurs pertinents à l’élaboration de stratégies d’atténuation ciblées (titre officiel : Comparative genomics of Campylobacter strains prevalent in Canadian poultry production associated with human disease: identification of biomarkers relevant to the development of targeted mitigation strategies). 2019-2020.
  • Inglis GD (CP), Uwiera RRE, Abbott DW, Brumer H, Selinger LB, Metz G, Bruce H. Conseil de recherches avicoles du Canada (grappe des sciences avicoles). Projet: Atténuation de l’inflammation intestinale pour la santé des volailles et de la production avicole (titre officiel: Mitigation of intestinal inflammation for poultry and production health). 2018-2023.
  • Inglis GD (CP), Taboada EN, Uwiera RRE, Abbott DW. Conseil de recherches avicoles du Canada (grappe des sciences avicoles). Projet: Atténuation rationnelle des souches pertinentes de Campylobacter jejuni dans la filière de production de poulets de chair (titre officiel: Rationale-based mitigation of relevant Campylobacter jejuni strains within the broiler production continuum). 2018-2023.
  • Abbott DW (CP), Inglis GD, Slominski B, Thomas D. Alberta Agriculture Funding Consortium. Projet: Pipeline de recherche pour la mise au point d’enzymes fibrolytiques sur mesure pour améliorer la digestibilité du tourteau de canola destiné aux animaux d’élevage monogastriques (titre officiel: Discovery pipeline for rapid development of tailored fibrolytic enzymes that improve the digestibility of canola meal for monogastric livestock)" 2018-2020.
  • Kalmokoff M (CP), Inglis GD (co-CP), Bezanson G, Ells T, Jones T, Guévremont É, Schwartzkopf-Genswein K, Hebb D, Eberl H, Uwiera R, Brooks S, Selinger B. Agriculture et Agroalimentaire Canada. Projet: Mise au point d’une culture d’exclusion compétitive ciblant Escherichia coli O157:H7 chez les bovins (titre officiel: Development of a competitive exclusion culture targeting Escherichia coli O157:H7 in cattle). 2018-2019.
  • Brumer H (CP), Inglis GD (co-CP), Abbott DW, Uwiera RRE. Canadian Glycomics Network (GlycoNet). Projet: Vectorisation de médicaments par oligosaccharides pour le traitement de maladies inflammatoires entériques chez l'homme et le bétail (titre officiel: Glyco-caged drug delivery to treat enteric inflammatory diseases in humans and livestock). 2017-2019.
  • Inglis GD (CP), Abbott DW, Thomas D, Selinger LB, Uwiera T, Kastelic JP, Taboada E, Carrillo C, Amoako K, Waddington L, Uwiera RRE, Selinger LB, Boras VF, Suttorp VV. Agriculture et Agroalimentaire Canada. Projet : Innovations visant à atténuer les sous-types de Campylobacter jejuni dans la chaîne d'approvisionnement de la volaille (titre officiel: Novel Innovations to mitigate Campylobacter jejuni subtypes in the poultry supply chain). 2016-2019.
  • Abbott DW (CP), Inglis GD (co-CP), Thomas D, Gilbert H, Martens E, Uwiera R, Uwiera T, Kastelic J, Metz G, Selinger LB, Koegler DP. Agriculture et Agroalimentaire Canada. Projet : Solutions non antimicrobiennes pour améliorer la santé immunitaire innée, la résistance à la colonisation et le rendement environnemental des porcs (titre officiel: Non-antimicrobial alternatives for improving innate immune health, colonization resistance, and environmental performance of swine). 2016-2019.
  • Uwiera RRE, Inglis GD (co-CP), Abbott DW, Selinger LB, Uwiera T, Kastelic JP, Boras VF, Koegler DP. Alberta Livestock and Meat Agency. Projet : Nouvelle thérapeutique sans antibiotiques pour la prise en charge des maladies inflammatoires aiguës et chroniques chez les mammifères d’élevage (titre officiel: A novel non-antibiotic therapeutic innovation for acute and chronic inflammatory enteric disease management in mammalian livestock). 2016-2020.

Énoncés de recherches/projets

  • Microbiologie entérique
  • Santé intestinale
  • Immunologie
  • Solutions de rechange aux antibiotiques pour la production animale

Prix et études

  • Ph.D., microbiologie, Université Simon Fraser (1996)
  • M.Sc. (distinction), microbiologie, Université de Guelph (1989)
  • B.Sc. (distinction), microbiologie, Université de l'Alberta (1985)

Principales publications

  1. Moote, P.E., Bescucci, D.M., Polo, R.O., Uwiera, R.R.E., Inglis, G.D. (2021). Comparison of Strategies for Isolating Anaerobic Bacteria from the Porcine Intestine. Applied and Environmental Microbiology, [online] 87(9), 1-23. http://dx.doi.org/10.1128/AEM.00088-21

    2021 - View publication details

  2. Douglas Inglis, G., Wright, B.D., Sheppard, S.A., Wade Abbott, D., Oryschak, M.A., Montina, T. (2021). Expeller-pressed canola (Brassica napus) meal modulates the structure and function of the cecal microbiota, and alters the metabolome of the pancreas, liver, and breast muscle of broiler chickens. Animals, [online] 11(2), 1-23. http://dx.doi.org/10.3390/ani11020577

    2021 - View publication details

  3. Douglas Inglis, G., Ramezani, N., Taboada, E.N., Boras, V.F., Uwiera, R.R.E. (2021). Analysis of Campylobacter jejuni Subtype Distribution in the Chicken Broiler Production Continuum: a Longitudinal Examination To Identify Primary Contamination Points. Applied and Environmental Microbiology, [online] 87(3), 1-20. http://dx.doi.org/10.1128/AEM.02001-20

    2021 - View publication details

  4. Inglis, G.D., Taboada, E.N., Boras, V.F. (2021). Rates of fluoroquinolone resistance in domestically acquired campylobawecter jejuni are increasing in people living within a model study location in canada. Canadian Journal of Microbiology, [online] 67(1), 37-52. http://dx.doi.org/10.1139/cjm-2020-0146

    2021 - View publication details

  5. Bescucci, D.M., Clarke, S.T., Brown, C.L.J., Boras, V.F., Montina, T., Uwiera, R.R.E., Inglis, G.D. (2020). The absence of murine cathelicidin-related antimicrobial peptide impacts host responses enhancing Salmonella enterica serovar Typhimurium infection. Gut Pathogens, [online] 12(1), http://dx.doi.org/10.1186/s13099-020-00386-1

    2020 - View publication details

  6. Zaytsoff, S.J.M., Uwiera, R.R.E., Douglas Inglis, G. (2020). Physiological stress mediated by corticosterone administration alters intestinal bacterial communities and increases the relative abundance of clostridium perfringens in the small intestine of chickens. Microorganisms, [online] 8(10), 1-16. http://dx.doi.org/10.3390/microorganisms8101518

    2020 - View publication details

  7. Inglis, G.D., Gusse, J.F., House, K.E., Shelton, T.G., Taboada, E.N. (2020). Clinically Relevant Campylobacter jejuni Subtypes Are Readily Found and Transmitted within the Cattle Production Continuum but Present a Limited Foodborne Risk. Applied and Environmental Microbiology, [online] 86(6), http://dx.doi.org/10.1128/AEM.02101-19

    2020 - View publication details

  8. Bescucci, D.M., Moote, P.E., Polo, R.O., Uwiera, R.R.E., Inglis, G.D. (2020). Salmonella enterica Serovar Typhimurium Temporally Modulates the Enteric Microbiota and Host Responses To Overcome Colonization Resistance in Swine. Applied and Environmental Microbiology, [online] 86(21), http://dx.doi.org/10.1128/AEM.01569-20

    2020 - View publication details

  9. Lange, M.E., Uwiera, R.R.E., Inglis, G.D. (2019). Housing Gnotobiotic Mice in Conventional Animal Facilities. Current protocols in mouse biology, [online] 9(1), e59. http://dx.doi.org/10.1002/cpmo.59

    2019 - View publication details

  10. Inglis, G.D., Duke, G.M., Goettel, M.S., Kabaluk, J.T., Ortega-Polo, R. (2019). Biogeography and genotypic diversity of metarhizium brunneum and metarhizium robertsii in northwestern North American soils, 65(4), 261-281. http://dx.doi.org/10.1139/cjm-2018-0297

    2019 - View publication details

  11. Pluvinage, B., Grondin, J.M., Amundsen, C., Klassen, L., Moote, P.E., Xiao, Y., Thomas, D., Pudlo, N.A., Anele, A., Martens, E.C., Inglis, G.D., Uwiera, R.E.R., Boraston, A.B., Abbott, D.W. (2018). Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont. Nature Communications, [online] 9(1), http://dx.doi.org/10.1038/s41467-018-03366-x

    2018 - View publication details

  12. Brown, K., Abbott, D.W., Uwiera, R.R.E., Inglis, G.D. (2018). Removal of the cecum affects intestinal fermentation, enteric bacterial community structure, and acute colitis in mice. Gut Microbes, [online] 9(3), 218-235. http://dx.doi.org/10.1080/19490976.2017.1408763

    2018 - View publication details

  13. Webb, A.L., Selinger, L.B., Taboada, E.N., Inglis, G.D. (2018). Subtype-specific selection for resistance to fluoroquinolones but not to tetracyclines is evident in Campylobacter jejuni isolates from beef cattle in confined feeding operations in Southern Alberta, Canada. Applied and Environmental Microbiology, [online] 84(7), http://dx.doi.org/10.1128/AEM.02713-17

    2018 - View publication details

  14. Jones, D.R., Thomas, D., Alger, N., Ghavidel, A., Douglas Inglis, G., Wade Abbott, D. (2018). SACCHARIS: An automated pipeline to streamline discovery of carbohydrate active enzyme activities within polyspecific families and de novo sequence datasets. Biotechnology for Biofuels, [online] 11(1), http://dx.doi.org/10.1186/s13068-018-1027-x

    2018 - View publication details

  15. Jiminez, J.A., Uwiera, T.C., Wade Abbott, D., Uwiera, R.R.E., Inglis, G.D. (2017). Butyrate supplementation at high concentrations alters enteric bacterial communities and reduces intestinal inflammation in mice infected with Citrobacter rodentium, 2(4), http://dx.doi.org/10.1128/mSphere.00243-17

    2017 - View publication details

  16. Golubov, A., Byeon, B., Woycicki, R., Inglis, G.D., Kovalchuk, I. (2017). Transcriptome of Arabidopsis thaliana plants treated with the human pathogen Campylobacter jejuni. Biocatalysis and Agricultural Biotechnology, [online] 11 259-267. http://dx.doi.org/10.1016/j.bcab.2017.07.016

    2017 - View publication details

  17. Buchanan, C.J., Webb, A.L., Mutschall, S.K., Kruczkiewicz, P., Barker, D.O.R., Hetman, B.M., Gannon, V.P.J., Abbott, D.W., Thomas, J.E., Inglis, G.D., Taboada, E.N. (2017). A genome-wide association study to identify diagnostic markers for human pathogenic campylobacter jejuni strains, 8(JUN), http://dx.doi.org/10.3389/fmicb.2017.01224

    2017 - View publication details

  18. Leblanc, D., Inglis, G.D., Boras, V.F., Brassard, J., Houde, A. (2017). The prevalence of enteric RNA viruses in stools from diarrheic and non-diarrheic people in southwestern Alberta, Canada. Archives of Virology, [online] 162(1), 117-128. http://dx.doi.org/10.1007/s00705-016-3063-9

    2017 - View publication details

  19. Webb, A.L., Taboada, E.N., Selinger, L.B., Boras, V.F., Douglas Inglis, G. (2017). Prevalence and diversity of waterborne Arcobacter butzleri in southwestern Alberta, Canada. Canadian Journal of Microbiology, [online] 63(4), 330-340. http://dx.doi.org/10.1139/cjm-2016-0745

    2017 - View publication details

  20. Jiminez, J.A., Uwiera, T.C., Abbott, D.W., Uwiera, R.R.E., Inglis, G.D. (2016). Impacts of resistant starch and wheat bran consumption on enteric inflammation in relation to colonic bacterial community structures and short-chain fatty acid concentrations in mice, 8(1), http://dx.doi.org/10.1186/s13099-016-0149-6

    2016 - View publication details

Installation de recherche

5403 1st Avenue South
Lethbridge, AB T1J 4B1
Canada

Affiliations

  • Professeur Adjoint, Université de Lethbridge, départements des Sciences biologiques et des Neurosciences
  • Professeur Adjoint, Université de l'Alberta, Département des sciences agricoles, alimentaires et nutritionnelles
  • Professeur Adjoint, Université de Calgary, Faculté de médecine vétérinaire

Language

Anglais