Dr. Carolyn Fitzsimmons
Dr Fitzsimmons is co-located at the University of Alberta and works in the areas of beef production and molecular genetics. She has a particular interest in the genetic control of residual feed intake, and fetal programing via epigenetics.
Recherche et / ou projets en cours
2019 – Chercheuse principale « Nutritional Epigenetic Effects in Cattle ». (AAC, services votés, 2019-2023)
2019 – Collaboratrice « Development of functional genomic prediction platform for industry application ». (Chercheurs principaux : C. Li et J. Basarab, Genome Alberta, 2019-2020)
2018 – Collaboratrice « 2018F095R - Genetic and microbial markers for rumen functions and implications in improving cattle feed efficiency ». (Chercheuse principale : L. Guan, Alberta Agriculture and Forestry, 2018-2020)
2018 – Collaboratrice « Genetic analyses of feed intake, feed efficiency, female fertility, and cow lifetime productivity in beef cattle raised under two environments. » (BCRC, 2018-2023)
Énoncés de recherches/projets
- La prise alimentaire résiduelle (RFI) et la production de méthane chez les bovins, ainsi que l’amélioration générale de l’efficacité et de la durabilité de la production de viande bovine.
- Régulation de l’expression des gènes par des moyens alimentaires (nutrigénomique).
- Potentiels génétiques différents des réponses individuelles aux changements de régime alimentaire (nutrigénétique).
- Changements permanents de l’expression génique pouvant être programmés dans la génération suivante par la nutrition ou d’autres facteurs influant sur la génération parentale (épigénétique).
En utilisant les modifications de l’expression génique dues à l’alimentation ou à d’autres traitements, on peut mieux comprendre le fonctionnement des systèmes biologiques et appliquer ces connaissances à l’amélioration de la production de viande bovine.
- ration parentale (épigénétique).
Principales publications
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Behrouzi A., Fitzsimmons C., McKeown L., Basarab J., Bork E. 2022. Methane and carbon dioxide emissions from crossbred beef cattle grazing native pastures. Poster and talk at the 8th International Greenhouse Gas & Animal Agriculture Conference, Orlando, FL, USA. June 2022.
2022 - Consulter les détails de la publication
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Na SW., Zhou M., Bork E., Fitzsimmons C., Guan L. 2022. Assessment of rumen and fecal short chain fatty acids profiles and microbial populations in rumen fluid and feces of beef cows under two different feeding regimes. 2022 Animal Nutrition Conference of Canada, Saskatoon, Canada. May 2022.
2022 - Consulter les détails de la publication
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Foroutan, A., Fitzsimmons, C., Mandal, R., Berjanskii, M.V., Wishart, D.S. (2020). Serum metabolite biomarkers for predicting residual feed intake (RFI) of young angus bulls. Metabolites, [online] 10(12), 1-20. http://dx.doi.org/10.3390/metabo10120491
2020 - Consulter les détails de la publication
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Mukiibi, R., Johnston, D., Vinsky, M., Fitzsimmons, C., Stothard, P., Waters, S.M., Li, C. (2020). Bovine hepatic miRNAome profiling and differential miRNA expression analyses between beef steers with divergent feed efficiency phenotypes. Scientific Reports, [online] 10(1), http://dx.doi.org/10.1038/s41598-020-73885-5
2020 - Consulter les détails de la publication
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Johnson, C., Fitzsimmons, C., Kovalchuk, I., Kastelic, J., Thundathil, J. (2020). Testis-specific changes in gene expression of post-pubertal beef bulls divergent for residual feed intake and exposure to different pre-natal diets, 60(12), 1491-1502. http://dx.doi.org/10.1071/AN19524
2020 - Consulter les détails de la publication
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Foroutan, A., Fitzsimmons, C., Mandal, R., Piri‐moghadam, H., Zheng, J., Guo, A., Li, C., Guan, L.L., Wishart, D.S. (2020). The bovine metabolome. Metabolites, [online] 10(6), 1-26. http://dx.doi.org/10.3390/metabo10060233
2020 - Consulter les détails de la publication
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Hadinia, S.H., Carneiro, P.R.O., Fitzsimmons, C.J., Bédécarrats, G.Y., Zuidhof, M.J. (2020). Post-photostimulation energy intake accelerated pubertal development in broiler breeder pullets. Poultry Science, [online] 99(4), 2215-2229. http://dx.doi.org/10.1016/j.psj.2019.11.065
2020 - Consulter les détails de la publication
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Añez-Osuna, F., Penner, G.B., Campbell, J., Dugan, M.E.R., Fitzsimmons, C.J., Jefferson, P.G., Lardner, H.A., McKinnon, J.J. (2019). Level and source of fat in the diet of gestating beef cows: I. Effects on the prepartum performance of the dam and birth weight of the progeny. Journal of Animal Science, [online] 97(7), 3103-3119. http://dx.doi.org/10.1093/jas/skz171
2019 - Consulter les détails de la publication
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Añez-Osuna, F., Penner, G.B., Campbell, J., Dugan, M.E.R., Fitzsimmons, C.J., Jefferson, P.G., Lardner, H.A., McKinnon, J.J. (2019). Level and source of fat in the diet of gestating beef cows. II. Effects on the postpartum performance of the dam and the progeny. Journal of Animal Science, [online] 97(7), 3120-3141. http://dx.doi.org/10.1093/jas/skz172
2019 - Consulter les détails de la publication
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Li, F., Li, C., Chen, Y., Liu, J., Zhang, C., Irving, B., Fitzsimmons, C., Plastow, G., Guan, L.L. (2019). Host genetics influence the rumen microbiota and heritable rumen microbial features associate with feed efficiency in cattle. Microbiome, [online] 7(1), http://dx.doi.org/10.1186/s40168-019-0699-1
2019 - Consulter les détails de la publication
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Añez-Osuna, F., Penner, G.B., Campbell, J., Damiran, D., Dugan, M.E.R., Fitzsimmons, C.J., Jefferson, P.G., McKinnon, J.J., Lardner, H.A. (2019). Effects of postpartum fat supplementation and source on the reproductive performance of lactating young beef cows grazing cool-season grass pastures. Applied Animal Science, [online] 35(2), 185-198. http://dx.doi.org/10.15232/aas.2018-01791
2019 - Consulter les détails de la publication
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Akanno, E.C., Ekine-Dzivenu, C., Chen, L., Vinsky, M., Abo-Ismail, M.K., Macneil, M.D., Plastow, G., Basarab, J., Li, C., Fitzsimmons, C. (2019). Evaluation of a genomic-enhanced sorting system for feeder cattle. Journal of Animal Science, [online] 97(3), 1066-1075. http://dx.doi.org/10.1093/jas/skz026
2019 - Consulter les détails de la publication
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Hare, K.S., Wood, K.M., Fitzsimmons, C., Penner, G.B. (2019). Oversupplying metabolizable protein in late gestation for beef cattle: Effects on postpartum ruminal fermentation, blood metabolites, skeletal muscle catabolism, colostrum composition, milk yield and composition, and calf growth performance. Journal of Animal Science, [online] 97(1), 437-455. http://dx.doi.org/10.1093/jas/sky413
2019 - Consulter les détails de la publication
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Hare, K.S., Wood, K.M., Acton, K., Fitzsimmons, C., Penner, G.B. (2019). Oversupplying metabolizable protein in late gestation for beef cattle: Effects on prepartum BW, ruminal fermentation, nitrogen balance, and skeletal muscle catabolism. Journal of Animal Science, [online] 97(1), 407-423. http://dx.doi.org/10.1093/jas/sky410
2019 - Consulter les détails de la publication
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Johnson, C., Fitzsimmons, C., Colazo, M., Li, C., Kastelic, J., Thundathil, J. (2019). Impacts of residual feed intake and pre-natal diet on reproductive potential of bulls. Animal Production Science, [online] 59(10), 1827-1836. http://dx.doi.org/10.1071/AN18301
2019 - Consulter les détails de la publication
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F Añez-Osuna, G Penner, C Fitzsimmons, M Dugan, J Campbell, P Jefferson, H Lardner, J McKinnon, 351 Effects of level and source of fat in the diet of gestating beef cows on progeny performance., Journal of Animal Science, Volume 96, Issue suppl_3, December 2018, Page 175, https://doi.org/10.1093/jas/sky404.381
2018 - Consulter les détails de la publication
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Mukiibi, R., Vinsky, M., Keogh, K.A., Fitzsimmons, C., Stothard, P., Waters, S.M., Li, C. (2018). Transcriptome analyses reveal reduced hepatic lipid synthesis and accumulation in more feed efficient beef cattle, 8(1), http://dx.doi.org/10.1038/s41598-018-25605-3
2018 - Consulter les détails de la publication
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Li, X., Yan, Q., Tang, S., Tan, Z., Fitzsimmons, C.J., Yi, K. (2018). Effects of maternal feed intake restriction during pregnancy on the expression of growth regulation, imprinting and epigenetic transcription-related genes in foetal goats, 198 90-98. http://dx.doi.org/10.1016/j.anireprosci.2018.09.005
2018 - Consulter les détails de la publication
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Difford, G.F., Plichta, D.R., Løvendahl, P., Lassen, J., Noel, S.J., Højberg, O., Wright, A.-D.G., Zhu, Z., Kristensen, L., Nielsen, H.B., Guldbrandtsen, B., Sahana, G. (2018). Host genetics and the rumen microbiome jointly associate with methane emissions in dairy cows, 14(10), http://dx.doi.org/10.1371/journal.pgen.1007580
2018 - Consulter les détails de la publication
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Ekine-Dzivenu C, Akanno EC, Chen L, McKeown L, Irving B, Baker L, Vinsky M, Miller S, Wang Z, Crowley J, Colazo M, Ambrose D, Juarez M, Bruce H, MacNeil MD, Plastow G, Basarab J, Li C, & Fitzsimmons C. (2018) Improvement of cow feed efficiency using molecular breeding values for residual feed intake - The “Kinsella Breeding Project”. In: Proceedings of the World Congress on Genetics Applied to Livestock Production. vol. Electronic Poster Session - Genetic Gain - Breeding Strategies 2: 809.
2018 - Consulter les détails de la publication
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