Non-Antibiotic approaches at drying-off for treating and preventing intramammary infections: A protocol for a systematic review and meta-Analysis

Citation

Francoz, D., Wellemans, V., Roy, J.-P., Lacasse, P., Ordonez-Iturriaga, A., Labelle, F., Dufour, S. (2016). Non-Antibiotic approaches at drying-off for treating and preventing intramammary infections: A protocol for a systematic review and meta-Analysis, 17(2), 169-175. http://dx.doi.org/10.1017/S1466252316000177

Plain language summary

Intramammary infection treatment and prevention at drying-off is one of the leading causes for using antimicrobials on dairy farms. In organic dairy production, however, use of antibiotic is restricted. The objective of the current manuscript is to describe the protocol used for conducting a systematic review of the literature on non-antibiotic strategies that can be used on dairy cows at dry-off to treat and prevent intramammary infection. To be included in the review, articles will have to: 1) be published after 1970; 2) be written in English, French, or Spanish; 3) use a study design such as a controlled trial, an observational study, or an experimental study conducted in vivo; 4) be conducted on commercial dairy cows (studies conducted on tropical breeds, as well as other ruminant and non-ruminant species will be excluded); 5) investigate a non-antibiotic intervention used at dry off such as anti-inflammatory drugs, teat sealant, homeopathic, phytotherapeutic, or biological products; and finally, 6) report on an outcome such as IMI incidence and elimination rates over the dry period, the prevalence of IMI at calving, or clinical mastitis incidence at beginning of following lactation. Titles and abstracts, then full articles will be reviewed independently by three reviewers for inclusion. The planned systematic review will be the first to colligate in a coherent whole all studies investigating non-antibiotic strategies for treating and preventing intramammary infection at drying-off.

Abstract

Copyright © Cambridge University Press 2017Â.Intramammary infection (IMI) treatment and prevention at drying-off is one of the leading causes for using antimicrobials on dairy farms. The objective of the current paper is to describe the protocol used for conducting a systematic review of the literature on non-Antibiotic strategies that can be used on dairy cows at dry off to treat and prevent IMI. Relevant literature will be identified using a combination of database search strategies and iterative screening of references. To be included in the review, articles will have to: (1) be published after 1969; (2) be written in English, French, or Spanish; (3) use a study design such as a controlled trial, an observational study, or an experimental study conducted in vivo; (4) be conducted on commercial dairy cows; (5) investigate a non-Antibiotic intervention used at dry off; and finally, (6) report on a relevant mastitis outcome. Titles and abstracts, then full articles will be reviewed for inclusion. Specific data will be extracted and risk of bias will be assessed for all included articles. The planned systematic review will be the first to colligate, in a coherent whole, studies investigating non-Antibiotic strategies for treating and preventing IMI at drying-off.

Publication date

2016-12-01

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