Characterization of (16R) and (16S)-hydroxyroquefortine C; Diastereomeric metabolites from Penicillium crustosum DAOM 215343

Citation

Trimble, L.A., Sumarah, M.W., Blackwell, B.A., Wrona, M.D., Miller, J.D. (2012). Characterization of (16R) and (16S)-hydroxyroquefortine C; Diastereomeric metabolites from Penicillium crustosum DAOM 215343. Tetrahedron Letters, [online] 53(8), 956-958. http://dx.doi.org/10.1016/j.tetlet.2011.12.052

Abstract

Two diastereomeric metabolites (16R) and (16S)-hydroxyroquefortine C were characterized from Penicillium crustosum DAOM 215343. The 16S metabolite is reported for the first time along with evidence for the absolute stereochemistry of both. The metabolites were originally detected by LC-NMR and the structures of the subsequently isolated metabolites were elucidated by HRMS and NMR. © 2011 Elsevier Ltd. All rights reserved.

Publication date

2012-02-22

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