Sylvie Cloutier, Ph.D.

• 4DWheat:
  • To produce reference genome assemblies for six Aegilops species;
  • To perform pan-genome analyses of 50 Aegilops and Triticum genomes using long-range reference-guided assemblies;
  • To perform SNP discovery and diversity analyses using low coverage short reads;
  • To produce genomic data and bioinformatics analyses of five backcross populations and 25 Nested Association Mapping (NAM) populations derived from 30 synthetic wheats to improve cross design and selection to increase the genetic diversity of the D genome from Ae. tauschii.
• Wheat Pre-Breeding Platform:
  • To genotype and phenotype a collection of wheat, progenitors, synthetics and wild relatives for leaf rust, stripe rust, Fusarium head blight and powdery mildew;
  • To perform a genome wide association study for all traits and identify genes and markers for wheat improvement.
• Flax Cadmium:
  • To sequence high and low cadmium accessions and to perform GWAS analysis for cadmium accumulation in flax.
• Flax Diseases:
  • To develop markers and isolate genes for resistance to pasmo, powdery mildew and Fusarium wilt in flax.
• Wheat Epigenetics:
  • To study gene expression mechanisms in synthetic wheats through RNASeq and  microRNAs.
• Recent Publications:
  • Walkowiak S, Gao L, Monat C, Haberer G, Kassa MT, Brinton J, Ramirez-Gonzalez RH, Kolodziej MC, Delorean E, Thambugala D, Klymiuk V, Byrns B, Gundlach H, Bandi V, Siri JN, Nilsen K, Aquino C, Himmelbach A, Copetti D, Ban T, Venturini L, Bevan M, Clavijo B, Koo D-H, Ens J, Wiebe K, N’Diaye A, Fritz AK, Gutwin C, Fiebig A, Fosker C, Fu BX, Accinelli GG, Gardner KA, Fradgley N, Gutierrez-Gonzalez J, Halstead-Nussloch G, Hatakeyama M, Koh CS, Deek J, Costamagna AC, Fobert P, Heavens D, Kanamori H, Kawaura K, Kobayashi F, Krasileva K, Kuo T, McKenzie N, Murata K, Nabeka Y, Paape T, Padmarasu S, Percival-Alwyn L, Kagale S, Scholz U, Sese J, Juliana P, Singh R, Shimizu-Inatsugi R, Swarbreck D, Cockram J, Budak H, Tameshige T, Tanaka T, Tsuji H, Wright J, Wu J, Steuernagel B, Small I, Cloutier S, Keeble-Gagnère G, Muehlbauer G, Tibbets J, Nasuda S, Melonek J, Hucl PJ, Sharpe AG, Clark M, Legg E, Bharti A, Langridge P, Hall A, Uauy C, Mascher M, Krattinger SG, Handa H, Shimizu KK, Distelfeld A, Chalmers K, Keller B, Mayer KFX, Poland J, Stein N, McCartney CA, Spannagl M, Wicker T, Pozniak CJ (2020) Multiple wheat genomes reveal global variation in modern breeding. Nature (doi.org/10.1038/s41586-020-2961-x)
  • Fatima F, McCallum BD, Pozniak CJ, Hiebert C, McCartney C, Fedak G, You FM, Cloutier S (2020) Resistance gene cloning from a wild crop relative by sequence capture and association genetics. Frontiers Plant Sci (doi: 10.3389/fpls.2020.583738)
  • Sertse D, You FM, Ravichandran S, Soto-Cerda BJ, Duguid S, Cloutier S (2020) Loci harboring genes with important role in drought and related abiotic stress responses in flax revealed by multiple GWAS models. Theor Appl Genet Online first Oct 12 (doi: 10.1007/s00122-020-03691-0)
  • Khan N, You FM, Datla R, Ravichandran S, Jia B, Cloutier S (2020) Genome-wide identification of ATP binding cassette (ABC) transporter and heavy metal associated (HMA) gene families in flax (Linum usitatissimum L.). BMC Genomics 21:722 (doi: 10.1186/s12864-020-07121-9)
  • Rajagopalan N, Lu Y, Burton IW, Monteil-Rivera F, Halasz A, Reimer E, Tweidt R, Brule-Babel A, Kutcher HR, You FM, Cloutier S, Cuperlovic-Culf M, Hiebert CW, McCallum BD, Loewen MC*(2020) A phenylpropanoid diglyceride associates with the leaf rust resistance Lr34res gene in wheat. Phytochemistry 178:112456 (doi.org/10.1016/j.phytochem.2020.112456)
  • You FM, Cloutier S (2020) Mapping quantitative trait loci onto chromosome-scale pseudomolecules in flax. Methods Protoc 3:E28 (doi: 10.3390/mps3020028)
  • Soto-Cerda BJ, Cloutier S, Gagardo HA, Aravena G, Quian R, You FM (2020) Drought response of flax accessions and identification of quantitative trait nucleotides (QTNs) governing agronomic and root traits by genome-wide association analysis. Mol Breeding 40:15 (doi.org/10.1007/s11032-019-1096-y)
  • Shafiei-Koij F, Cloutier S, Ravichandran S, Barthet V, Rodrigue N, Mirlohi A, Majidi MMM (2020) Evolution of Carthamus species revealed through sequence analyses of the fad2 gene family. Physiol Mol Biol Plant 26: 419-432 (doi.org/10.1007/s12298-019-00739-4)
  • Sertse D, You FM, Ravichandran S, Cloutier S (2020) The Complex Genetic Architecture of Early Root and Shoot Traits in Flax Revealed by Genome-Wide Association Analyses. Front Plant Sci 10:1483 (doi.org/10.3389/fpls.2019.01483)

Fields of Science

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