Sijo Joseph (Thandapilly), Ph.D.

Image Sijo Joseph (Thandapilly)
Research Scientist

Investigating the nutritional and anti-nutritional bioactive components from agricultural based resources and their impact on human health. Developing novel methodologies for the study of carbohydrate and or protein, oil and minor components structure function, and their utilization for improvement of cereal grain end products.

Current research and/or projects

  • Investigating the potential of avenanthramides on glycemic control- a novel marketable
    attribute for Manitoban Oats.. 

  • Developing a platform comprising novel experimental tools for improving the health
    benefits of Canadian agricultural products. 

  • Evaluating the effect of processing methods, genotype and environment on the
    extractability of protein from oats and characterizing physiochemical and nutritional
    attributes of oat protein. 

  • Evaluating the health attributes of Oat derived proteins.

  • Evaluation of protein digestibility and glycemic response of pulse based
    products using in vitro experimental platform. 


Professional activities / interests

Voting Member, Wheat, Rye and Triticale Quality Committee, Prairie Grain Development
Committee (PGDC).
American Association of Cereal Chemist’s (AACC) Bioactive Technical Committee
Member, Agriculture and Agri-Food Canada Career Development Committee
Editor, Journal of Food Biochemistry

Editorial board member of Journal of Clinical Nutrition & Dietetics
Canada Standards ISO committee member related to Cereals and Pulses standards
development (ISO/TC34/SC4).
Member of Wheat Initiative group: Improving Wheat Quality for Processing and Health
Champion, Indigenous Student Recruitment Initiative, Agriculture and Agri-Food Canada

Education and awards

2007 – 2012      University of Manitoba, Canada                                                 Ph.D. (Physiology)

2002– 2004      Bharathiar University, India                                                   M.Sc. (Biotechnology)

1999– 2002      University of Calicut, India                                                             B.Sc. (Chemistry)

Scholarships/Research awards

2012-2014                   NSERC, Canada Post-doctoral visiting fellowship

2012-2013                   Manitoba Health Research Council PhD Studentship (declined)

2010-2012                   Manitoba Health Research Council PhD Studentship


  • Best oral presentation Award at Functional Foods and Nutraceutical Symposium


  • Dr. Grant Pierce Award for Excellence in Cardiovascular Physiology
  • Have a Heart Bursary Award from Canadian Cardiovascular society
  • Award of excellence in the CIHR National level Poster competition
  • Best Poster Presentation at Manitoba Health Research Poster competition
  • International Graduate student scholarship


  • Best Poster Presentation Award from Institute of Cardiovascular Sciences
  • Rated second in the Fletcher Gordon PhD Fellowship
  • International Graduate Student Scholarship


  • ICS Studentship Award from Institute of Cardiovascular Sciences
  • International Graduate Student Entrance Scholarship

Travel Awards


  • Canadian Oxidative Stress Consortium travel award
  • University of Manitoba Graduate student Travel award


  • Canadian Hypertension Society travel award
  • University of Manitoba Graduate student Travel award


  • Graduate student International travel award
  • Manitoba Agri-Health Research Network International Travel Award

Key publications

  1. Thandapilly, S.J., Louis, X.L., Yang, T., Stringer, D.M., Yu, L., Zhang, S., Wigle, J., Kardami, E., Zahradka, P., Taylor, C., Anderson, H.D., Netticadan, T. (2011). Resveratrol prevents norepinephrine induced hypertrophy in adult rat cardiomyocytes, by activating NO-AMPK pathway. European Journal of Pharmacology, [online] 668(1-2), 217-224.

    2011 - View publication details

  2. Wojciechowski, P., Louis, X.L., Thandapilly, S.J., Yu, L., and Netticadan, T. (2010). "Potential of Resveratrol in Preventing the Development of Heart Failure.", Current Chemical Biology, 4(1), pp. 84-88.

    2010 - View publication details

  3. Behbahani, J., Thandapilly, S.J., Louis, X.L., Huang, Y., Shao, Z., Kopilas, M.A., Wojciechowski, P., Netticadan, T., and Anderson, H.D. (2010). "Resveratrol and Small Artery Compliance and Remodeling in the Spontaneously Hypertensive Rat.", American Journal of Hypertension, 23(12), pp. 1273-1278. doi : 10.1038/ajh.2010.161

    2010 - View publication details

  4. Wojciechowski, P., Juric, D., Louis, X.L., Thandapilly, S.J., Yu, L., Taylor, C.G., and Netticadan, T. (2010). "Resveratrol Arrests and Regresses the Development of Pressure Overload- but Not Volume Overload-Induced Cardiac Hypertrophy in Rats.", Journal of Nutrition, 140(5), pp. 962-968. doi : 10.3945/jn.109.115006

    2010 - View publication details

  5. Juric, D., Yao, X.-H., Thandapilly, S.J., Louis, X.L., Cantor, E.J.F., Chaze, B., Wojciechowski, P., Vasanji, Z., Yang, T., Wigle, J., and Netticadan, T. (2010). "Defects in ryanodine receptor are associated with systolic dysfunction in rats subjected to volume overload.", Experimental Physiology, 95(8), pp. 869-879. doi : 10.1113/expphysiol.2009.052100

    2010 - View publication details

  6. Behbahani, J., Kopilas, M.A., Wojciechowski, P., Thandapilly, S.J., Netticadan, T., and Anderson, H.D. (2009). "Blood pressure independent correction of resistance artery structure but not intrinsic wall stiffness by resveratrol in the spontaneously hypertensive rat.", Canadian Journal of Cardiology, 25(Suppl. 1B), pp. 30B. (Abstract)

    2009 - View publication details

  7. Louis, X.L., Thandapilly, S.J., Yu, L., Wojciechowski, P., Yang, T., Stringer, D.M., Douville, J.M., Cheung, D.Y.C., Massaeli, H., Zhang, S., Wigle, J., Kardami, E., Zahradka, P., and Netticadan, T. (2009). "Resveratrol prevents norepinephrine induced hypertrophy in adult cardiomyocytes.", 6th Canadian Oxidative Stress Conference, Winnipeg, MB, Canada, May 7-10, 2009, pp. 100.

    2009 - View publication details

Research facility

Route 100, Unit 100-101
Morden, MB R6M 1Y5


Research Scientist, Agriculture and Agri-Food Canada   

Adjunct Professor, Department of Human Nutritional Sciences, University of  Manitoba, Canada