Sijo Joseph (Thandapilly), Ph.D.
Investigating the nutritional and anti-nutritional bioactive components from agricultural based resources and their impact on human health. Developing novel methodologies for the study of carbohydrate and or protein, oil and minor components structure function, and their utilization for improvement of cereal grain end products.
Current research and/or projects
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Investigating the potential of avenanthramides on glycemic control- a novel marketable
attribute for Manitoban Oats.. -
Developing a platform comprising novel experimental tools for improving the health
benefits of Canadian agricultural products. -
Evaluating the effect of processing methods, genotype and environment on the
extractability of protein from oats and characterizing physiochemical and nutritional
attributes of oat protein. -
Evaluating the health attributes of Oat derived proteins.
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Evaluation of protein digestibility and glycemic response of pulse based
products using in vitro experimental platform.
Professional activities / interests
Voting Member, Wheat, Rye and Triticale Quality Committee, Prairie Grain Development
Committee (PGDC).
American Association of Cereal Chemist’s (AACC) Bioactive Technical Committee
Member, Agriculture and Agri-Food Canada Career Development Committee
Editor, Journal of Food Biochemistry
Editorial board member of Journal of Clinical Nutrition & Dietetics
Canada Standards ISO committee member related to Cereals and Pulses standards
development (ISO/TC34/SC4).
Member of Wheat Initiative group: Improving Wheat Quality for Processing and Health
Champion, Indigenous Student Recruitment Initiative, Agriculture and Agri-Food Canada
Education and awards
2007 – 2012 University of Manitoba, Canada Ph.D. (Physiology)
2002– 2004 Bharathiar University, India M.Sc. (Biotechnology)
1999– 2002 University of Calicut, India B.Sc. (Chemistry)
Scholarships/Research awards
2012-2014 NSERC, Canada Post-doctoral visiting fellowship
2012-2013 Manitoba Health Research Council PhD Studentship (declined)
2010-2012 Manitoba Health Research Council PhD Studentship
2011
- Best oral presentation Award at Functional Foods and Nutraceutical Symposium
2010
- Dr. Grant Pierce Award for Excellence in Cardiovascular Physiology
- Have a Heart Bursary Award from Canadian Cardiovascular society
- Award of excellence in the CIHR National level Poster competition
- Best Poster Presentation at Manitoba Health Research Poster competition
- International Graduate student scholarship
2009
- Best Poster Presentation Award from Institute of Cardiovascular Sciences
- Rated second in the Fletcher Gordon PhD Fellowship
- International Graduate Student Scholarship
2007
- ICS Studentship Award from Institute of Cardiovascular Sciences
- International Graduate Student Entrance Scholarship
Travel Awards
2012
- Canadian Oxidative Stress Consortium travel award
- University of Manitoba Graduate student Travel award
2011
- Canadian Hypertension Society travel award
- University of Manitoba Graduate student Travel award
2009
- Graduate student International travel award
- Manitoba Agri-Health Research Network International Travel Award
Additional links
Key publications
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Sharifi, M., C Moffat, D. Ensing, S. Debnath, J. MacDonald, J. Pollard-Flamand, K. Fong, L. Malunga, S. Joseph, V. Marshall, B. Rabie, T. Nelson, C. Harlton, and D. Martin. 2022. Revitalizing knowledge of scwicw’s growing conditions, propagation and preservation. Report to Neskonlith Indian Band.
2022 - View publication details
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Malunga, L.N., Ames, N., Khorshidi, A.S., Thandapilly, S.J., Yan, W., Dyck, A., Waterer, J., Malcolmson, L., Cuthbert, R., Sopiwnyk, E., Scanlon, M.G. (2021). Association of asparagine concentration in wheat with cultivar, location, fertilizer, and their interaction. Food Chemistry, [online] 344 http://dx.doi.org/10.1016/j.foodchem.2020.128630
2021 - View publication details
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Wijekoon, C., Acharya, S.N., Siow, Y.L., Sura, S., Thandapilly, S., Sabra, A. (2021). Canadian sainfoin and fenugreek as forage and functional foods. Crop Science, [online] 61(1), 1-20. http://dx.doi.org/10.1002/csc2.20280
2021 - View publication details
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19. Heather Blewett, Nancy Ames, Jay Petkau, Sijo Joseph, Sora Ludwig, Randomized Controlled Crossover Dose-Response Trial Shows Low Dose (2 g) Barley β-Glucan Provided in Waffles Lowers Post-Prandial Glycaemic Response In Healthy Adults, Current Developments in Nutrition, Volume 4, Issue Supplement_2, June 2020, Page 615, https://doi.org/10.1093/cdn/nzaa049_008
2020 - View publication details
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Malunga, L.N., Ames, N.P., Masatcioglu, M.T., Khorshidi, A.S., Thandapilly, S.J., Cuthbert, R.D., Sopiwnyk, E., Scanlon, M.G. (2019). Free asparagine concentrations in Canadian hard red spring wheat cultivars. Canadian Journal of Plant Science, [online] 99(3), 338-347. http://dx.doi.org/10.1139/cjps-2018-0134
2019 - View publication details
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Malunga, L.N., Joseph Thandapilly, S., Ames, N. (2018). Cereal-derived phenolic acids and intestinal alpha glucosidase activity inhibition: Structural activity relationship. Journal of Food Biochemistry, [online] 42(6), http://dx.doi.org/10.1111/jfbc.12635
2018 - View publication details
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Salimi Khorshidi, A., Thandapilly, S.J., Ames, N. (2018). Application of low-intensity ultrasound as a rapid, cost-effective tool to wheat screening: A systematic frequency selection. Journal of Cereal Science, [online] 82 190-197. http://dx.doi.org/10.1016/j.jcs.2018.06.011
2018 - View publication details
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Thandapilly, S.J., Ndou, S.P., Wang, Y., Nyachoti, C.M., Ames, N.P. (2018). Barley β-glucan increases fecal bile acid excretion and short chain fatty acid levels in mildly hypercholesterolemic individuals. Food and Function, [online] 9(6), 3092-3096. http://dx.doi.org/10.1039/c8fo00157j
2018 - View publication details
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Wang, Y., Harding, S.V., Thandapilly, S.J., Tosh, S.M., Jones, P.J.H., Ames, N.P. (2017). Barley β-glucan reduces blood cholesterol levels via interrupting bile acid metabolism. British Journal of Nutrition, [online] 118(10), 822-829. http://dx.doi.org/10.1017/S0007114517002835
2017 - View publication details
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Ibrahim, N.H.M., Thandapilly, S.J., Jia, Y., Netticadan, T., Aukema, H. (2016). Soy Protein Alleviates Hypertension and Fish Oil Improves Diastolic Heart Function in the Han:SPRD-Cy Rat Model of Cystic Kidney Disease. Lipids, [online] 51(5), 635-642. http://dx.doi.org/10.1007/s11745-015-4095-8
2016 - View publication details
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Ames, N., Blewett, H., Storsley, J., Thandapilly, S.J., Zahradka, P., Taylor, C. (2015). A double-blind randomised controlled trial testing the effect of a barley product containing varying amounts and types of fibre on the postprandial glucose response of healthy volunteers. British Journal of Nutrition, [online] 113(9), 1373-1383. http://dx.doi.org/10.1017/S0007114515000367
2015 - View publication details
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Raj, P., Lieben Louis, X., Thandapilly, S.J., Movahed, A., Zieroth, S., and Netticadan, T. (2014). "Potential of resveratrol in the treatment of heart failure.", Life Sciences, 95(2), pp. 63-71. doi : 10.1016/j.lfs.2013.12.011
2014 - View publication details
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Louis, X.L., Thandapilly, S.J., Kalt, W., Vinqvist-Tymchuk, M., Aloud, B.M., Raj, P., Yu, L., Le, H., Netticadan, T. (2014). Blueberry polyphenols prevent cardiomyocyte death by preventing calpain activation and oxidative stress, 5(8), 1785-1794. http://dx.doi.org/10.1039/c3fo60588d
2014 - View publication details
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Wang, Y., Thandapilly, S.J., Harding, S.V., Tosh, S.M., Jones, P.J.H., and Ames, N.P. (2013). "Barley β-Glucan Consumption Decreases Serum Cholesterol Levels and Increases 7 alpha-Hydroxy-4-Cholesten-3-One Levels in Moderately Hypercholesterolemic Adults.", Experimental Biology 2013, Boston, MA, USA, April 20-24, 2013.
2013 - View publication details
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Movahed, A., Nabipour, I., Lieben Louis, X., Thandapilly, S.J., Yu, L., Kalantarhormozi, M., Rekabpour, S.J., Netticadan, T. (2013). Antihyperglycemic effects of short term resveratrol supplementation in type 2 diabetic patients, 2013 http://dx.doi.org/10.1155/2013/851267
2013 - View publication details
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Thandapilly, S.J., Louis, X.L., Yu, L., Vinqvist-Tymchuk, M.R., Kalt, W., and Netticadan, T. (2012). "Blueberry fractions prevent norepinephrine induced cardiomyocyte hypertrophy and cell death.", 10th International Symposium on Vaccinium and Other Superfruits, Maastricht, Limburg, The Netherlands, June 17-22, 2012.
2012 - View publication details
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Movahed, A., Yu, L., Thandapilly, S.J., Louis, X.L., and Netticadan, T. (2012). "Resveratrol protects adult cardiomyocytes against oxidative stress mediated cell injury.", Archives of Biochemistry and Biophysics, 527(2), pp. 74-80. doi : 10.1016/j.abb.2012.05.002
2012 - View publication details
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Louis, X.L., Murphy, R., Thandapilly, S.J., Yu, L., Netticadan, T. (2012). Garlic extracts prevent oxidative stress, hypertrophy and apoptosis in cardiomyocytes: A role for nitric oxide and hydrogen sulfide, 12 http://dx.doi.org/10.1186/1472-6882-12-140
2012 - View publication details
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Thandapilly, S.J., Louis, X.L., Yang, T., Stringer, D.M., Yu, L., Zhang, S., Wigle, J., Kardami, E., Zahradka, P., Taylor, C., Anderson, H.D., Netticadan, T. (2011). Resveratrol prevents norepinephrine induced hypertrophy in adult rat cardiomyocytes, by activating NO-AMPK pathway. European Journal of Pharmacology, [online] 668(1-2), 217-224. http://dx.doi.org/10.1016/j.ejphar.2011.06.042
2011 - View publication details
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Wojciechowski, P., Louis, X.L., Thandapilly, S.J., Yu, L., and Netticadan, T. (2010). "Potential of Resveratrol in Preventing the Development of Heart Failure.", Current Chemical Biology, 4(1), pp. 84-88.
2010 - View publication details
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Research facility
Expertise
Affiliations
Research Scientist, Agriculture and Agri-Food Canada
Adjunct Professor, Department of Human Nutritional Sciences, University of Manitoba, Canada