Sijo Joseph (Thandapilly), Ph.D.

Image Sijo Joseph (Thandapilly)
Research Scientist

Investigating the nutritional and anti-nutritional bioactive components from agricultural based resources and their impact on human health. Developing novel methodologies for the study of carbohydrate and or protein, oil and minor components structure function, and their utilization for improvement of cereal grain end products.

Current research and/or projects

  • Investigating the potential of avenanthramides on glycemic control- a novel marketable
    attribute for Manitoban Oats.. 

  • Developing a platform comprising novel experimental tools for improving the health
    benefits of Canadian agricultural products. 

  • Evaluating the effect of processing methods, genotype and environment on the
    extractability of protein from oats and characterizing physiochemical and nutritional
    attributes of oat protein. 

  • Evaluating the health attributes of Oat derived proteins.

  • Evaluation of protein digestibility and glycemic response of pulse based
    products using in vitro experimental platform. 
     

 

Professional activities / interests

Voting Member, Wheat, Rye and Triticale Quality Committee, Prairie Grain Development
Committee (PGDC).
American Association of Cereal Chemist’s (AACC) Bioactive Technical Committee
Member, Agriculture and Agri-Food Canada Career Development Committee
Editor, Journal of Food Biochemistry

Editorial board member of Journal of Clinical Nutrition & Dietetics
Canada Standards ISO committee member related to Cereals and Pulses standards
development (ISO/TC34/SC4).
Member of Wheat Initiative group: Improving Wheat Quality for Processing and Health
Champion, Indigenous Student Recruitment Initiative, Agriculture and Agri-Food Canada
 

Education and awards

2007 – 2012      University of Manitoba, Canada                                                 Ph.D. (Physiology)

2002– 2004      Bharathiar University, India                                                   M.Sc. (Biotechnology)

1999– 2002      University of Calicut, India                                                             B.Sc. (Chemistry)

Scholarships/Research awards

2012-2014                   NSERC, Canada Post-doctoral visiting fellowship

2012-2013                   Manitoba Health Research Council PhD Studentship (declined)

2010-2012                   Manitoba Health Research Council PhD Studentship

2011

  • Best oral presentation Award at Functional Foods and Nutraceutical Symposium

2010                           

  • Dr. Grant Pierce Award for Excellence in Cardiovascular Physiology
  • Have a Heart Bursary Award from Canadian Cardiovascular society
  • Award of excellence in the CIHR National level Poster competition
  • Best Poster Presentation at Manitoba Health Research Poster competition
  • International Graduate student scholarship

2009                           

  • Best Poster Presentation Award from Institute of Cardiovascular Sciences
  • Rated second in the Fletcher Gordon PhD Fellowship
  • International Graduate Student Scholarship

2007                           

  • ICS Studentship Award from Institute of Cardiovascular Sciences
  • International Graduate Student Entrance Scholarship

Travel Awards

2012                           

  • Canadian Oxidative Stress Consortium travel award
  • University of Manitoba Graduate student Travel award

2011                           

  • Canadian Hypertension Society travel award
  • University of Manitoba Graduate student Travel award

2009                           

  • Graduate student International travel award
  • Manitoba Agri-Health Research Network International Travel Award

Key publications

  1. Wijekoon, C., Acharya, S.N., Siow, Y.L., Sura, S., Thandapilly, S., Sabra, A. (2021). Canadian sainfoin and fenugreek as forage and functional foods. Crop Science, [online] 61(1), 1-20. http://dx.doi.org/10.1002/csc2.20280

    2021 - View publication details

  2. 19. Heather Blewett, Nancy Ames, Jay Petkau, Sijo Joseph, Sora Ludwig, Randomized Controlled Crossover Dose-Response Trial Shows Low Dose (2 g) Barley β-Glucan Provided in Waffles Lowers Post-Prandial Glycaemic Response In Healthy Adults, Current Developments in Nutrition, Volume 4, Issue Supplement_2, June 2020, Page 615, https://doi.org/10.1093/cdn/nzaa049_008

    2020 - View publication details

  3. Malunga, L.N., Ames, N.P., Masatcioglu, M.T., Khorshidi, A.S., Thandapilly, S.J., Cuthbert, R.D., Sopiwnyk, E., Scanlon, M.G. (2019). Free asparagine concentrations in Canadian hard red spring wheat cultivars. Canadian Journal of Plant Science, [online] 99(3), 338-347. http://dx.doi.org/10.1139/cjps-2018-0134

    2019 - View publication details

  4. Salimi Khorshidi, A., Thandapilly, S.J., Ames, N. (2018). Application of low-intensity ultrasound as a rapid, cost-effective tool to wheat screening: A systematic frequency selection. Journal of Cereal Science, [online] 82 190-197. http://dx.doi.org/10.1016/j.jcs.2018.06.011

    2018 - View publication details

  5. Thandapilly, S.J., Ndou, S.P., Wang, Y., Nyachoti, C.M., Ames, N.P. (2018). Barley β-glucan increases fecal bile acid excretion and short chain fatty acid levels in mildly hypercholesterolemic individuals. Food and Function, [online] 9(6), 3092-3096. http://dx.doi.org/10.1039/c8fo00157j

    2018 - View publication details

  6. Wang, Y., Harding, S.V., Thandapilly, S.J., Tosh, S.M., Jones, P.J.H., Ames, N.P. (2017). Barley β-glucan reduces blood cholesterol levels via interrupting bile acid metabolism. British Journal of Nutrition, [online] 118(10), 822-829. http://dx.doi.org/10.1017/S0007114517002835

    2017 - View publication details

  7. Ibrahim, N.H.M., Thandapilly, S.J., Jia, Y., Netticadan, T., Aukema, H. (2016). Soy Protein Alleviates Hypertension and Fish Oil Improves Diastolic Heart Function in the Han:SPRD-Cy Rat Model of Cystic Kidney Disease. Lipids, [online] 51(5), 635-642. http://dx.doi.org/10.1007/s11745-015-4095-8

    2016 - View publication details

  8. Ames, N., Blewett, H., Storsley, J., Thandapilly, S.J., Zahradka, P., Taylor, C. (2015). A double-blind randomised controlled trial testing the effect of a barley product containing varying amounts and types of fibre on the postprandial glucose response of healthy volunteers. British Journal of Nutrition, [online] 113(9), 1373-1383. http://dx.doi.org/10.1017/S0007114515000367

    2015 - View publication details

  9. Raj, P., Lieben Louis, X., Thandapilly, S.J., Movahed, A., Zieroth, S., and Netticadan, T. (2014). "Potential of resveratrol in the treatment of heart failure.", Life Sciences, 95(2), pp. 63-71. doi : 10.1016/j.lfs.2013.12.011

    2014 - View publication details

  10. Louis, X.L., Thandapilly, S.J., Kalt, W., Vinqvist-Tymchuk, M., Aloud, B.M., Raj, P., Yu, L., Le, H., Netticadan, T. (2014). Blueberry polyphenols prevent cardiomyocyte death by preventing calpain activation and oxidative stress, 5(8), 1785-1794. http://dx.doi.org/10.1039/c3fo60588d

    2014 - View publication details

  11. Wang, Y., Thandapilly, S.J., Harding, S.V., Tosh, S.M., Jones, P.J.H., and Ames, N.P. (2013). "Barley β-Glucan Consumption Decreases Serum Cholesterol Levels and Increases 7 alpha-Hydroxy-4-Cholesten-3-One Levels in Moderately Hypercholesterolemic Adults.", Experimental Biology 2013, Boston, MA, USA, April 20-24, 2013.

    2013 - View publication details

  12. Movahed, A., Nabipour, I., Lieben Louis, X., Thandapilly, S.J., Yu, L., Kalantarhormozi, M., Rekabpour, S.J., Netticadan, T. (2013). Antihyperglycemic effects of short term resveratrol supplementation in type 2 diabetic patients, 2013 http://dx.doi.org/10.1155/2013/851267

    2013 - View publication details

  13. Thandapilly, S.J., Louis, X.L., Yu, L., Vinqvist-Tymchuk, M.R., Kalt, W., and Netticadan, T. (2012). "Blueberry fractions prevent norepinephrine induced cardiomyocyte hypertrophy and cell death.", 10th International Symposium on Vaccinium and Other Superfruits, Maastricht, Limburg, The Netherlands, June 17-22, 2012.

    2012 - View publication details

  14. Movahed, A., Yu, L., Thandapilly, S.J., Louis, X.L., and Netticadan, T. (2012). "Resveratrol protects adult cardiomyocytes against oxidative stress mediated cell injury.", Archives of Biochemistry and Biophysics, 527(2), pp. 74-80. doi : 10.1016/j.abb.2012.05.002

    2012 - View publication details

  15. Louis, X.L., Murphy, R., Thandapilly, S.J., Yu, L., Netticadan, T. (2012). Garlic extracts prevent oxidative stress, hypertrophy and apoptosis in cardiomyocytes: A role for nitric oxide and hydrogen sulfide, 12 http://dx.doi.org/10.1186/1472-6882-12-140

    2012 - View publication details

  16. Thandapilly, S.J., Louis, X.L., Yang, T., Stringer, D.M., Yu, L., Zhang, S., Wigle, J., Kardami, E., Zahradka, P., Taylor, C., Anderson, H.D., Netticadan, T. (2011). Resveratrol prevents norepinephrine induced hypertrophy in adult rat cardiomyocytes, by activating NO-AMPK pathway. European Journal of Pharmacology, [online] 668(1-2), 217-224. http://dx.doi.org/10.1016/j.ejphar.2011.06.042

    2011 - View publication details

  17. Wojciechowski, P., Louis, X.L., Thandapilly, S.J., Yu, L., and Netticadan, T. (2010). "Potential of Resveratrol in Preventing the Development of Heart Failure.", Current Chemical Biology, 4(1), pp. 84-88.

    2010 - View publication details

  18. Behbahani, J., Thandapilly, S.J., Louis, X.L., Huang, Y., Shao, Z., Kopilas, M.A., Wojciechowski, P., Netticadan, T., and Anderson, H.D. (2010). "Resveratrol and Small Artery Compliance and Remodeling in the Spontaneously Hypertensive Rat.", American Journal of Hypertension, 23(12), pp. 1273-1278. doi : 10.1038/ajh.2010.161

    2010 - View publication details

  19. Wojciechowski, P., Juric, D., Louis, X.L., Thandapilly, S.J., Yu, L., Taylor, C.G., and Netticadan, T. (2010). "Resveratrol Arrests and Regresses the Development of Pressure Overload- but Not Volume Overload-Induced Cardiac Hypertrophy in Rats.", Journal of Nutrition, 140(5), pp. 962-968. doi : 10.3945/jn.109.115006

    2010 - View publication details

  20. Juric, D., Yao, X.-H., Thandapilly, S.J., Louis, X.L., Cantor, E.J.F., Chaze, B., Wojciechowski, P., Vasanji, Z., Yang, T., Wigle, J., and Netticadan, T. (2010). "Defects in ryanodine receptor are associated with systolic dysfunction in rats subjected to volume overload.", Experimental Physiology, 95(8), pp. 869-879. doi : 10.1113/expphysiol.2009.052100

    2010 - View publication details

Research facility

Route 100, Unit 100-101
Morden, MB R6M 1Y5
Canada

Affiliations

Research Scientist, Agriculture and Agri-Food Canada   

Adjunct Professor, Department of Human Nutritional Sciences, University of  Manitoba, Canada

Language

English