Mylène Blais, Ph.D.

Current research and/or projects

The main objectives related to Dr Blais’s research activities are: 1) To elaborate new strategies to replace the use of antibiotics in the swine industry by improving pig’s immunity and gut health through microbiota optimisation; 2) To develop new technologies and approaches to study swine immune system and gut defenses in response to stress and pathogens; 3) To give a better understanding of swine intestinal and immune development.

Research and/or project statements

  • Early interventions supporting the development of a potent immune system for robust and healthy piglets without the need of AMU using alfalfa silage and cranberry-derived proanthocyanidins applied to the sows and piglets in maternity and nursery.

  • Determine the impact of birth weight and gain weight during lactation on piglets’ immune status, gut development and microbiota.

  • Use of bovine colostrum as a feeding strategy to decrease the use of antibiotics at weaning by improving piglets intestinal defenses and immunity

  • Develop in vitro models of porcine intestinal epithelial cell and immune cell cultures and co-cultures to study intestinal and immune response to enteric pathogens, evaluate the potential of various bioactive products to alleviate inflammation and maintain intestinal epithelial integrity.

  • Evaluate the potential of neonatal fecal transplant to improve piglets’ microbiota diversity, gut development and immunity.

Key publications

  1. 2019 Ontario Ministry of Agriculture, Food and Rural Affairs - FOOD SAFETY RESEARCH FORUM; October 9, Guelph, Ontario, Canada

    2019 - View publication details

  2. Lessard, M., Blais, M., Beaudoin, F., Deschene, K., Verso, L.L., Bissonnette, N., Lauzon, K., Guay, F. (2018). Piglet weight gain during the first two weeks of lactation influences the immune system development. Veterinary Immunology and Immunopathology, [online] 206 25-34. http://dx.doi.org/10.1016/j.vetimm.2018.11.005

    2018 - View publication details

Research facility

2000 College Street
Sherbrooke, QC J1M 1Z3
Canada

Language

English
French

Other languages

Anglais