Mr. Mark Bonnell
Provide state of the science leadership on the fate, behaviour, toxicology and exposure of chemicals to support chemical management decisions made by the Government of Canada and global partners
Current research and/or projects
Working to ensure that chemicals assessed under the Chemicals Management Plan (CMP) best reflect the global science of ecological risk assessment
- Provide expert scientific opinion and direction related to the risk assessment of new and existing chemcials assessed under the Chemicals Management Plan
- Coordination and integration of global fate, toxicology and exposure sciences for new and existing substances assessed by Environment and Climate Change Canada
- Provide expert advice on the application and interpretation of quantitative structure-activity relationship (QSAR) models and mass balance environmental fate models for a variety of substance chemistries assessed under the Canadian Environmental Protection Act
- Develop and enhance the expertise of regulatory scientists within the Science and Risk Assessment Directorate (SRAD) through technical training
- Act as a conduit between global expert groups (e.g., OECD, HESI, SETAC, ECETOC, CEFIC, UNEP) and regulatory scientists within SRAD
Professional activities / interests
Risk assessment of over 1000 new and existing substances
QSAR PBT/POPs, long-range transport modelling and environmental fate and bioaccumulation kinetic mass balance modelling
EC representative at international expert forums on hazard (PBT) and risk assessment science (OECD, SETAC Global Advisory Groups, HESI)
Development of bioaccumulation assessment science
Education and awards
Honours B.Sc. - Environmental Science, Trent University 1990 (environmental toxicology)
Diploma Forestry Technician - Algonquin College of Applied Arts and Technology 1985
Environment Canada Recognition Award for Scientific Contribution and Leadership 2007
New Substances Program Certificate of Appreciation for the Assessment of over 1000 New Substances 2007
Natural Sciences and Engineering Research Council (NSERC) Undergraduate Research Award 1989
Trent University Academic Bursary Awards 1986, 1987,1988, 1989
Algonquin Student Union Contribution Award as Director of Athletics 1984
Key publications
Connors, K. A., Beasley, A. , Barron, M. G., Belanger, S. E., Bonnell, M. , Brill, J. L., de Zwart, D. , Kienzler, A. , Krailler, J. , Otter, R. , Phillips, J. L. and Embry, M. R. (2019), Creation of a curated aquatic toxicology database: EnviroTox. Environ Toxicol Chem. doi:10.1002/etc.4382
Bonnell, M., Zidek, A., Griffiths, A. and Gutzman, D. 2018. Fate and exposure modeling in regulatory chemical evaluation: new directions from retrospection. Environ. Sci.: Processes Impacts, 20: 20-31.
Bonnell, M. and Demers. M. 2016. Science Approach Document: Ecological Risk Classification of Organic Substances. Environment and Climate Change Canada. July. http://www.ec.gc.ca/ese-ees/default.asp?lang=En&n=A96E2E98-1
Gobas, L. Burkhard, M. Bonnell, B. Doucette, K. Sappington, E. Verbruggen, B. Hope, J. Arnot, J. Tarazona. 2015. Terrestrial Bioaccumulation Models for Bioaccumulation Screening and Exposure Assessment for Organic Substances. In press, Integ. Environ. Assess. Manage.
Princz,J, Bonnell, M, Ritchie, E, Velicogna, J, Robidoux,P-Y and Scroggins, R. 2014. Estimation of the bioaccumulation potential of a non-chlorinated bisphenol and an ionogenic xanthene dye to Eisenia andrei in field-collected soils, in conjunction with predictive In silico profiling. Environ. Toxicol. Chem. 33(2): 308-316.
Mackay, D., Hughes, DM, Romano, M and M. Bonnell. 2014. The role of persistence in chemical evaluations. Integrated Environmental Assessment and Management. 10(4): 588–594.
Buser AM, MacLeod M, Scheringer M, Mackay D, Bonnell M, Russell MH, DePinto JV, Hungerbühler K. 2012. Good modeling practice guidelines for applying multimedia models in chemical assessments. Integrated Environmental Assessment and Management. 8(4): 703-8.
Nichols, J.W., M. Bonnell, S. Dimitrov, B. Escher, B., X. Han and N. Kramer. 2009. Bioaccumulation Assessment Using Predictive Approaches. Integrated Environmental Assessment and Management 5(4): 577-597.
Arnot, J.A., M. Arnot, D. Mackay, Y.Couillard, D. MacDonald, M. Bonnell and P. Doyle. 2009. Molecular Size Cut-off Criteria for Screening Bioaccumulation Potential: Fact or Fiction? Integrated Environmental Assessment and Management.
Arnot, J.A., W. Meylan, J. Tunkel, P. Howard, D. Mackay, M. Bonnell and R.S. Boethling. 2009. A quantitative structure activity relationship for predicting metabolic biotransformation rates for organic chemcials in fish. Environ. Toxicol. Chem. 28: 1168-1177.
Erhardt, S., A. Weisbrod, J. Sahi, H. Segner, M. James, J. Nichols, I. Schultz, S. Erhardt, C. Cowan-Ellsberry, M. Bonnell and B. Hoeger. 2009. The state of in vitro science for use in bioaccumulation assessments for fish. Environ. Toxicol. Chem. 28(1): 86-96.
Arnot, J., D. MacKay, M. Bonnell and T. Parkerton. 2008. A database of fish biotransformation rates. Environ. Toxicol. Chem. 27(11): 2263-2270.
Arnot, J., D. MacKay and M. Bonnell. 2008. Estimating Biotransformation Rates in Fish. Environ. Toxicol. Chem. 27(2): 341-351.
Parkerton, T.F., J.A. Arnot, A.V. Weisbrod, C. Russom, R.A. Hoke, K. Woodburn, T. Traas, M. Bonnell, L.P. Burkhard and M.A. Lampi. 2008. Guidance for evaluating in-vivo fish bioaccumulation data. Integrated Environmental Assessment and Management 4:139-155.
Weisbrod, A.V., LP. Burkhard, J. Arnot, O. Mekenyan, P. Howard, C. Russom, R. Boethling, Y. Sakuratani, T. Traas, T. Bridges, C. Lutz, M. Bonnell, K. Woodburn and T. Parkerton. Workgroup Report: Review of Fish Bioaccumulation Databases used to identify Persistent, Bioaccumulative, Toxic Substances. 2007. Environmental Health Perspectives. 15(2): 255-261.
Contact
Expertise
Affiliations
OECD QSAR Management Group
SETAC Global Advisory Group on Bioaccumulation
SETAC Global Advisory Group on Exposure Modelling
HESI Bioaccumulation Project Committee