Mark W Sumarah, Ph.D.

Image Mark W Sumarah
Research Scientist
  • Analytical and Natural Products Chemistry
  • Metabolomics
  • Mass Spectrometry
  • NMR

Current research and/or projects

Dr. Sumarah is an analytical and natural products chemist with expertise in the isolation, structural elucidation and analysis of small organic molecules from complex biological matrices using LC-MS and NMR. This includes extensive experience on the characterization and analysis of fungal secondary metabolites. The majority of his current research is focused on the development and implementation of better tools using mass spectrometry for the detection and monitoring of mycotoxins in the food production system and agricultural contaminants such as pharmaceuticals in the environment. These tools are being used for discovery of new emerging mycotoxins and to provide data on the fate and occurrence of pharmaceuticals in the environment to regulators. 

Research and/or project statements

  • Emerging mycotoxins in Canada
  • Fungal endophytes of blueberry plants and grapevines
  • Fungal culture collection chemical screening
  • LC-MS/MS analysis of micropollutants

Professional activities / interests

Discussion leader for the 2015 and 2017 Gordon Research Conferences on mycotoxins and phycotoxins held in Easton, MA

Session co-chair at the MycoRed North American Workshop, June 2012, Ottawa, ON

Member of the international advising committee and session chair for the 2016 World Mycotoxin Forum meeting held in Winnipeg, MB, June 2016

Education and awards

Ph.D. Chemistry - Specialization in Chemical Toxicology (2009) Carleton University, Ottawa, ON

M.Sc. Chemistry - Specialization in Chemical Toxicology (2002) Carleton University, Ottawa, ON

Award - Received the Arthur C. Neish Young Investigator Award from the Phytochemical Society of North America “for excellence in research in phytochemistry” (2012)

International experience and/or work

Joint (FAO/WHO) Expert Committee on Food Additives (JECFA) expert roster (2017-2021)

Key publications

  1. Trimble, L.A., Sumarah, M.W., Blackwell, B.A., Wrona, M.D., Miller, J.D. (2012). Characterization of (16R) and (16S)-hydroxyroquefortine C; Diastereomeric metabolites from Penicillium crustosum DAOM 215343, 53(8), 956-958. http://dx.doi.org/10.1016/j.tetlet.2011.12.052

    2012 - View publication details

  2. Baines, D.D.S., Erb, S.L., Turkington, T.K., Kuldau, G., Juba, J., Sumarah, M.W., Mazza, A., and Masson, E. (2011). "Characterization of Haemorrhagic Enteritis in Dairy Goats and the Effectiveness of Probiotic and Prebiotic Applications in Alleviating Morbidity and Production Losses.", Fungal Genomics & Biology, 1:1. doi : 10.4172/fgb.1000102

    2011 - View publication details

  3. Sumarah, M.W., Kesting, J.R., Sørensen, D., Miller, J.D. (2011). Antifungal metabolites from fungal endophytes of Pinus strobus, 72(14-15), 1833-1837. http://dx.doi.org/10.1016/j.phytochem.2011.05.003

    2011 - View publication details

  4. Baines, D.D.S., Erb, S.L., Sumarah, M.W., Lowe, R.M.S., Turkington, T.K., Sabau, E., Kuldau, G., Juba, J., Masson, L., Mazza, A., Roberts, R. (2011). "A prebiotic, Celmanax™, decreases Escherichia coli O157:H7 colonization of bovine cells and feed-associated cytotoxicity in vitro.", BMC Research Notes, 4:110. doi : 10.1186/1756-0500-4-110

    2011 - View publication details

  5. Sumarah, M.W., Puniani, E., Sørensen, D., Blackwell, B.A., Miller, J.D. (2010). Secondary metabolites from anti-insect extracts of endophytic fungi isolated from Picea rubens, 71(7), 760-765. http://dx.doi.org/10.1016/j.phytochem.2010.01.015

    2010 - View publication details

  6. Sumarah, M.W., Puniani, E., Sørensen, D., Blackwell, B.A., and Miller, J.D. (2009). "Characterization of metabolites from red spruce endophytes by LC-MS-SPE/NMR.", Gordon Research Conference on Mycotoxins and Phycotoxins, Colby-Sawyer College, New London, NH, USA, June 21-26, 2009. (Poster)

    2009 - View publication details

  7. Sumarah, M.W., Puniani, E., Blackwell, B.A., Miller, J.D. (2008). Characterization of polyketide metabolites from foliar endophytes of Picea glauca, 71(8), 1393-1398. http://dx.doi.org/10.1021/np800192f

    2008 - View publication details

  8. Sumarah, M.W., Adams, G.W., Berghout, J., Slack, G.J., Wilson, A.M., and Miller, J.D. (2008). "Spread and persistence of a rugulosin-producing endophyte in Picea glauca seedlings.", Mycological Research, 112(6), pp. 731-736. doi : 10.1016/j.mycres.2008.01.007

    2008 - View publication details

  9. Miller, J.D., Sumarah, M.W., and Adams, G.W. (2008). "Effect of a Rugulosin-producing Endophyte in Picea glauca on Choristoneura fumiferana.", Journal of Chemical Ecology, 34(3), pp. 362-368. doi : 10.1007/s10886-007-9412-0

    2008 - View publication details

  10. Sørensen, D., Raditsis, A., Trimble, L.A., Blackwell, B.A., Sumarah, M.W., Miller, J.D. (2007). Isolation and structure elucidation by LC-MS-SPE/NMR: PR toxin- and cuspidatol-related eremophilane sesquiterpenes from Penicillium roqueforti, 70(1), 121-123. http://dx.doi.org/10.1021/np060454v

    2007 - View publication details

  11. Nielsen, K.F., Sumarah, M.W., Frisvad, J.C., Miller, J.D. (2006). "Production of Metabolites from the Penicillium roqueforti Complex.", Journal of Agricultural and Food Chemistry, 54(10), pp. 3756-3763.

    2006 - View publication details

  12. Sumarah, M.W., Miller, J.D., and Blackwell, B.A. (2005). "Isolation and metabolite production by Penicillium roqueforti, P. paneum and P. crustosum isolated in Canada.", Mycopathologia, 159(4), pp. 571-577. doi : 10.1007/s11046-005-5257-7

    2005 - View publication details

Research facility

1391 Sandford Street
London, ON N5V 4T3
Canada

Affiliations

Adjunct Research Professor Western University, Department of Chemistry, London, ON

Adjunct Research Professor Carleton University, Department of Chemistry, Ottawa, ON

Language

English
French