Mark W Sumarah, Ph.D.

Image Mark W Sumarah
Research Scientist
  • Analytical and Natural Products Chemistry
  • Metabolomics
  • Mass Spectrometry
  • NMR

Current research and/or projects

Dr. Sumarah is an analytical and natural products chemist with expertise in the isolation, structural elucidation and analysis of small organic molecules from complex biological matrices using LC-MS and NMR. This includes extensive experience on the characterization and analysis of fungal secondary metabolites. The majority of his current research is focused on the development and implementation of better tools using mass spectrometry for the detection and monitoring of mycotoxins in the food production system and agricultural contaminants such as pharmaceuticals in the environment. These tools are being used for discovery of new emerging mycotoxins and to provide data on the fate and occurrence of pharmaceuticals in the environment to regulators. 

Research and/or project statements

  • Emerging mycotoxins in Canada
  • Fungal endophytes of blueberry plants and grapevines
  • Fungal culture collection chemical screening
  • LC-MS/MS analysis of micropollutants

Professional activities / interests

Discussion leader for the 2015 and 2017 Gordon Research Conferences on mycotoxins and phycotoxins held in Easton, MA

Session co-chair at the MycoRed North American Workshop, June 2012, Ottawa, ON

Member of the international advising committee and session chair for the 2016 World Mycotoxin Forum meeting held in Winnipeg, MB, June 2016

Education and awards

Ph.D. Chemistry - Specialization in Chemical Toxicology (2009) Carleton University, Ottawa, ON

M.Sc. Chemistry - Specialization in Chemical Toxicology (2002) Carleton University, Ottawa, ON

Award - Received the Arthur C. Neish Young Investigator Award from the Phytochemical Society of North America “for excellence in research in phytochemistry” (2012)

International experience and/or work

Joint (FAO/WHO) Expert Committee on Food Additives (JECFA) expert roster (2017-2021)

Key publications

  1. S. Sura, M.A. Henriquez, S. Walkowiak, D.A. Kaminski, A. Kirk, M.W. Sumarah, N. Kepeshchuk, J. Carlson, P. de Rocquigny and H. Derksen, “NX-Toxins from Fusarium graminearum isolates in western Canada”, Poster Presentation, World Mycotoxin Forum, 14th Conference, Antwerp, Belgium, Oct 9-11, 2023.

    2023 - View publication details

  2. S. Sura, M.A. Henriquez, S. Walkowiak, D.A. Kaminski, A. Kirk, M.W. Sumarah, N. Kepeshchuk, J. Carlson, P. de Rocquigny and H. Derksen, “NX-Toxins from Fusarium graminearum isolates in western Canada”, Poster Presentation, World Mycotoxin Forum, 14th Conference, Antwerp, Belgium, Oct 9-11, 2023.

    2023 - View publication details

  3. McDonald, K., Renaud, J.B., Pick, F.R., Miller, J.D., Sumarah, M.W., McMullin, D.R. (2021). Diagnostic Fragmentation Filtering for Cyanopeptolin Detection. Environmental Toxicology and Chemistry, [online] 40(4), 1087-1097. http://dx.doi.org/10.1002/etc.4941

    2021 - View publication details

  4. Renaud, J.B., Hoogstra, S., Quilliam, M.A., Sumarah, M.W. (2021). Normalization of LC-MS mycotoxin determination using the N-alkylpyridinium-3-sulfonates (NAPS) retention index system. Journal of Chromatography A, [online] 1639 http://dx.doi.org/10.1016/j.chroma.2021.461901

    2021 - View publication details

  5. Li, J., Sabourin, L., Renaud, J., Halloran, S., Singh, A., Sumarah, M., Dagnew, M., Ray, M.B. (2021). Simultaneous quantification of five pharmaceuticals and personal care products in biosolids and their fate in thermo-alkaline treatment. Journal of Environmental Management, [online] 278 http://dx.doi.org/10.1016/j.jenvman.2020.111404

    2021 - View publication details

  6. Walsh, J.P., DesRochers, N., Renaud, J.B., Seifert, K.A., Yeung, K.K.C., Sumarah, M.W. (2021). Identification of N,N′,N″-triacetylfusarinine C as a key metabolite for root rot disease virulence in American ginseng. Journal of Ginseng Research, [online] 45(1), 156-162. http://dx.doi.org/10.1016/j.jgr.2019.08.008

    2021 - View publication details

  7. Collins, S.L., Walsh, J.P., Renaud, J.B., McMillan, A., Rulisa, S., Miller, J.D., Reid, G., Sumarah, M.W. (2021). Improved methods for biomarker analysis of the big five mycotoxins enables reliable exposure characterization in a population of childbearing age women in Rwanda. Food and Chemical Toxicology, [online] 147 http://dx.doi.org/10.1016/j.fct.2020.111854

    2021 - View publication details

  8. Chakraborty, T., Balusani, D., Sabourin, L., Renaud, J., Sumarah, M., Nakhla, G., Ray, M.B. (2020). Fate of micropollutants in chemically enhanced primary treatment using recovered coagulants. Journal of Environmental Management, [online] 269 http://dx.doi.org/10.1016/j.jenvman.2020.110815

    2020 - View publication details

  9. Loi, M., Renaud, J.B., Rosini, E., Pollegioni, L., Vignali, E., Haidukowski, M., Sumarah, M.W., Logrieco, A.F., Mulè, G. (2020). Enzymatic transformation of aflatoxin B1 by Rh_DypB peroxidase and characterization of the reaction products. Chemosphere, [online] 250 http://dx.doi.org/10.1016/j.chemosphere.2020.126296

    2020 - View publication details

  10. Kelman, M.J., Renaud, J.B., Seifert, K.A., Mack, J., Yeung, K.K.C., Sumarah, M.W. (2020). Chemotaxonomic profiling of canadian alternaria populations using high-resolution mass spectrometry. Metabolites, [online] 10(6), http://dx.doi.org/10.3390/metabo10060238

    2020 - View publication details

  11. Des Rochers, N., Walsh, J.P., Renaud, J.B., Seifert, K.A., Yeung, K.K.C., Sumarah, M.W. (2020). Metabolomic profiling of fungal pathogens responsible for root rot in American ginseng. Metabolites, [online] 10(1), http://dx.doi.org/10.3390/metabo10010035

    2020 - View publication details

  12. Crippin, T., Limay-Rio, V., Renaud, J.B., Schaafsma, A.W., Sumarah, M.W., Miller, J.D. (2020). Fusarium graminearum populations from maize and wheat in Ontario, Canada. World Mycotoxin Journal, [online] 13(3), 355-366. http://dx.doi.org/10.3920/WMJ2019.2532

    2020 - View publication details

  13. Joshi, J., Renaud, J.B., Sumarah, M.W., Marsolais, F. (2019). Deciphering S-methylcysteine biosynthesis in common bean by isotopic tracking with mass spectrometry. Plant Journal, [online] 100(1), 176-186. http://dx.doi.org/10.1111/tpj.14438

    2019 - View publication details

  14. McMullin, D.R., Hoogstra, S., McDonald, K.P., Sumarah, M.W., Renaud, J.B. (2019). Natural Product Discovery with LC-MS/MS Diagnostic Fragmentation Filtering: Application for Microcystin Analysis. Journal of Visualized Experiments (JoVE), [online] 2019(147), http://dx.doi.org/10.3791/59712

    2019 - View publication details

  15. Walsh, J.P., Renaud, J.B., Hoogstra, S., McMullin, D.R., Ibrahim, A., Visagie, C.M., Tanney, J.B., Yeung, K.K.C., Sumarah, M.W. (2019). Diagnostic fragmentation filtering for the discovery of new chaetoglobosins and cytochalasins. Rapid Communications in Mass Spectrometry (RCM), [online] 33(1), 133-139. http://dx.doi.org/10.1002/rcm.8306

    2019 - View publication details

  16. Manoli, K., Morrison, L.M., Sumarah, M.W., Nakhla, G., Ray, A.K., Sharma, V.K. (2019). Pharmaceuticals and pesticides in secondary effluent wastewater: Identification and enhanced removal by acid-activated ferrate(VI). Water Research, [online] 148 272-280. http://dx.doi.org/10.1016/j.watres.2018.10.056

    2019 - View publication details

  17. Morrison, L.M., Renaud, J.B., Sabourin, L., Sumarah, M.W., Yeung, K.K.C., Lapen, D.R. (2018). High-throughput quantitation of neonicotinoids in lyophilized surface water by LC-APCI-MS/MS. Journal of AOAC International, [online] 101(6), 1940-1947. http://dx.doi.org/10.5740/jaoacint.17-0486

    2018 - View publication details

  18. Park, S.H., Li, F., Renaud, J., Shen, W., Li, Y., Guo, L., Cui, H., Sumarah, M., Wang, A. (2017). NbEXPA1, an α-expansin, is plasmodesmata-specific and a novel host factor for potyviral infection. Plant Journal, [online] 92(5), 846-861. http://dx.doi.org/10.1111/tpj.13723

    2017 - View publication details

  19. Daisley, B.A., Trinder, M., McDowell, T.W., Welle, H., Dube, J.S., Ali, S.N., Leong, H.S., Sumarah, M.W., Reid, G. (2017). Neonicotinoid-induced pathogen susceptibility is mitigated by Lactobacillus plantarum immune stimulation in a Drosophila melanogaster model. Scientific Reports, [online] 7(1), http://dx.doi.org/10.1038/s41598-017-02806-w

    2017 - View publication details

  20. Scott, I.M., Samara, R., Renaud, J.B., Sumarah, M.W. (2017). Plant growth regulator-mediated anti-herbivore responses of cabbage (Brassica oleracea) against cabbage looper Trichoplusia ni Hübner (Lepidoptera: Noctuidae). Pesticide Biochemistry and Physiology, [online] 141 9-17. http://dx.doi.org/10.1016/j.pestbp.2016.10.005

    2017 - View publication details

Research facility

1391 Sandford Street
London, ON N5V 4T3
Canada

Affiliations

Adjunct Research Professor Western University, Department of Chemistry, London, ON

Adjunct Research Professor Carleton University, Department of Chemistry, Ottawa, ON

Language

English
French