Jérôme Lapointe Ph. D.

Research Scientist

My research projects are seeking to improve the health, robustness and longevity of animals in swine  production through the development of nutritional strategies geared to controlling oxidative stress and optimizing energy metabolism.

Current research and/or projects

Development of genomics tools and management practices to promote animal health, metabolic efficiency, productivity and longevity, reduce their ecological footprint and promote value-added animal products.

Research and/or project statements

- Towards a restricted use of antibiotics and ZnO in pig production: Development of new nutrigenomics approaches based on a better understanding of the interactions between bacterial pathogens, mitochondrial function and zinc levels.

- Innovative micronutrient strategies for maximizing piglet’s robustness and performance during the pre- and post-weaning periods.

- Development of an innovative strategy targeting mitochondria for improving health and resistance of newly weaned piglets, decreasing the needs for antibiotics in swine production and improving food safety.

Professional activities / interests

- Oxidative stress

- Mitochondrial energy metabolism

- Nutrigenomics

- Alternative to antibiotics and heavy metals in swine production

Education and awards

- B. Sc. Biology, Université Laval, 1998.

- Certificate in genetic engeneering, Université Laval, 1998.

- M. Sc. Molecular and cellular biology, Université Laval, 2001.

- Ph. D. physiology-endocrinology, Université Laval, 2005.

- Postdoctorate, Biology, Université McGill, 2011.

International experience and/or work

- Deputy Editor, British Journal of Nutrition, Cambridge University Press.

Key publications

  1. Palin, M.F., Gariépy, C., Beaudry, D., Lapointe, J. and Kalbe, C. (2019) Protective effects of carnosine on hydrogen peroxide–induced oxidative stress in myoblast cells derived from porcine skeletal muscle. 65th International Congress of Meat Science and Technology 2019 in Potsdam/Berlin, Germany 04– 09 August 2019. (Abstract and Poster)

    2019 - View publication details

  2. Palin, M.F., Gariépy, C., Beaudry, D., Lapointe, J. and Kalbe, C. (2018) Carnosine prevents oxidative damage in porcine muscle cells. Canadian Meat Council's 98th Annual Conference, May 29-31, 2018, Montreal, Quebec.

    2018 - View publication details

  3. Beaulieu, D., Farmer, C., Brown, J., Lapointe, J. and Palin, M.F. Increasing sow milk yield and piglet growth via low-cost feeding and management strategies during gestation and/or lactation. In Swine Innovation Porc 2017-2018 Final Report. pp. 14-15.

    2018 - View publication details

  4. Talbot, G., Lessard, M., Yergeau, E., Gagnon, N., Lo Verso, L., Lapointe, J., Bissonnette, N., Bueno Dalto, D., Ouattara, B., Guay, F., and Matte, J.J. (2016). "Effects of different sources and routes of administration of copper and vitamins A and D on piglets gut microbiota.", Journal of Animal Science, 94(Supp. 2). (Abstract)

    2016 - View publication details

  5. Lo Verso, L., Matte, J.J., Talbot, G., Bissonnette, N., Lapointe, J., Gagnon, N., Ouattara, B., Guay, F., and Lessard, M. (2016). "Effects of different sources and routes of administration of copper and vitamins A and D on gut volatile fatty acids and gene expression involved in regulation of innate and acquired immunity in piglets.", Journal of Animal Science, 94(Supp. 2). (Abstract)

    2016 - View publication details

  6. Talbot, G., Lessard, M., Yergeau, E., Gagnon, N., Lo Verso, L., Lapointe, J., Bissonnette, N., Bueno Dalto, D., Ouattara, B., Guay, F., and Matte, J.J. (2016). "Microbiota of the small intestine of piglets affected by perinatal administration of copper and vitamins A and D.", 18th International Conference on Microbiota Buenos Engineering, Buenos Aires, Argentina, 27-28 October, 2016.

    2016 - View publication details

  7. Lapointe, J., Roy, C., Beaudry, D., Bergeron, N., Blanchet, I., Petit, H.V., and Palin, M.F. (2016) Effect of flax meal supplementation on oxidative stress and metabolic status of early lactation dairy cows infused with flax oil in the abomasum. Journal of Animal Science Vol. 94, E-Suppl. 5/Journal of Dairy Science Vol. 99, E-Suppl. 1. p. 684. (Abstract 1410) doi:10.2527/jam2016-1410

    2016 - View publication details

  8. Lapointe, J., Roy, C.S., Bergeron, N., Lavoie, M., Beaudry, D., Blanchet, I., Petit, H.V., and Palin, M.-F. (2015). "Negative energy balance is associated with inflammatory and oxidative stress conditions in early lactation dairy cows.", Society for Free Radical Biology and Medicine’s (SFRBM) Annual Meeting, Boston, MS, USA, November 18-21, 2015.

    2015 - View publication details

  9. Morisette, B., Lessard, M., Yergeau, E., Lapointe, J., Guay, F., Bissonnette, N., Matte, J.J., Letellier, A., Quessy, S., Bergeron, N., Beaulieu, C., and Talbot, G. (2014). "Influence of Feed Additives as an Alternative to Antibiotics on Gut Microbiota of Weaned Piglets Infected with Salmonella Typhimurium.", 114th General Meeting of the American Society for Microbiology, Boston, Massachusetts, USA, May 17-20, 2014.

    2014 - View publication details

  10. Lessard, M., Deschêne, K., Savard, C., Lapointe, J., Guay, F., and Chorfi, Y. (2014). "Effect of deoxynivalenol (DON) ingestion on expression of genes involved in intestinal integrity and immune response.", 2014 ADSA-ASAS Midwest Meeting, Iowa Events Center, Des Moines, Iowa, USA, March 17-19, 2014, # 163; Oral Présentation. (Abstract)

    2014 - View publication details

  11. Morissette, B., Lessard, M., Yergeau, E., Lapointe, J., Guay, F., Bissonnette, N., Matte, J.J., Letellier, A., Quessy, S., Bergeron, N., and Talbot, B.G. (2014). "Influence of Feed Additives as an Alternative to Antibiotics on Gut Microbiota of Weaned Piglets Infected with Salmonella Typhimurium.", 7ième Symposium du CRIPA, Hyacinthe, Québec, Canada, 3-4 juin 2014. (Poster)

    2014 - View publication details

  12. Lessard, M., Deschêne, K., Savard, C., Gagnon, A.-È., Lapointe, J., Pinilla, V.A., Guay, F., and Chorfi, Y. (2014). "Effect of deoxynivalenol (DON) ingestion on expression of genes involved in intestinal barrier and immune functions.", 7ième Symposium du CRIPA, Hyacinthe, Québec, Canada, 3-4 juin 2014, Présentation orale.

    2014 - View publication details

  13. Morisette, B., Lessard, M.-H., Yergeau, E., Lapointe, J., Guay, F., Bissonnette, N., Matte, J.J., Letellier, A., Quessy, S., Bergeron, N., Beaulieu, C., and Talbot, G. (2014). "Influence of Feed Additives as an Alternative to Antibiotics on Gut Microbiota of Weaned Piglets Infected with Salmonella Typhimurium.", 114th General Meeting of the American Society for Microbiology, Boston, Massachusetts, USA, May 17-20, 2014. (Abstract)

    2014 - View publication details

  14. Lapointe, J. (2014). "Mitochondria as promising targets for nutritional interventions aiming to improve performance and longevity of sows.", Journal of Animal Physiology and Animal Nutrition, 98(5), pp. 809-821. doi : 10.1111/jpn.12160

    2014 - View publication details

  15. Farmer, C., Lapointe, J., and Palin, M.-F. (2014). "Effects of the plant extract silymarin on prolactin concentrations mammary gland development, and oxidative stress in gestating gilts.", Journal of Animal Science, 92(7), pp. 2922-2930. doi : 10.2527/jas.2013-7118

    2014 - View publication details

  16. Lapointe, J. and Farmer, C. (2013). "Dietary supplementation with the plant extract silymarin protects gestating gilts from oxidative stress-related damage without affecting mitochondrial antioxidant defenses.", 7th Congress of the International Society of Nutrigenetics/Nutrigenomics (ISNN), Quebec City Convention Centre, Quebec City, Canada, October 5-8, 2013.

    2013 - View publication details

  17. Lapointe, J. (2013). "Improving sows longevity by using targeted nutritional interventions.", 49th Annual Eastern Nutrition Conference of the Animal Nutrition Association of Canada (ANAC), Hôtel Château Laurier, Québec City, QC, Canada, May 15-16, 2013, pp. 119-136.

    2013 - View publication details

  18. Lapointe, J. (2012). "Improving productivity and longevity of livestock by using a nutrigenomics approach targeting mitochondrial energy metabolism and oxidative stress status.", AAFC Scientific Symposium: Let’s talk science at DSRDC, Sherbrooke, QC, Canada, November 28, 2012.

    2012 - View publication details

  19. Lapointe, J., Roy, M., Audet, I., Beaudry, D., Palin, M.-F., Quesnel, H., Guay, F., and Matte, J.J. (2012). "Organic selenium and vitamin B6 synergize to up-regulate glutathione peroxidases (GPx) expression in dietary supplemented gilts.", Society for the Study of Reproduction 45th Annual Meeting and 18th Ovarian Workshop, Pennsylvania State University, State College, PA, USA, August 12-15, 2012, Abs. 469. (Abstract)

    2012 - View publication details

  20. Van Calsteren, M.-R., Gagnon, F., Lapointe, J., Guertin, N., and LaPointe, G. (2012). "Structure determination of the exopolysaccharide produced by Lactococcus lactis subsp. Cremoris strain JFR1.", MOOT XXV Mini NMR Symposium, Université Laval, Québec City, QC, Canada, October 20-21, 2012.

    2012 - View publication details

Research facility

2000 College Street
Sherbrooke, QC J1M 1Z3
Canada

Affiliations

- Adjuct professor, Biology, Université de Sherbrooke.

- Adjunct professor, Animal Science, Université Laval.

 

Language

English
French