Jérôme Lapointe Ph. D.

Research Scientist

My research projects are seeking to improve the health, robustness and longevity of animals in swine  production through the development of nutritional strategies geared to controlling oxidative stress and optimizing energy metabolism.

Current research and/or projects

Development of genomics tools and management practices to promote animal health, metabolic efficiency, productivity and longevity, reduce their ecological footprint and promote value-added animal products.

Research and/or project statements

- Towards a restricted use of antibiotics and ZnO in pig production: Development of new nutrigenomics approaches based on a better understanding of the interactions between bacterial pathogens, mitochondrial function and zinc levels.

- Innovative micronutrient strategies for maximizing piglet’s robustness and performance during the pre- and post-weaning periods.

- Development of an innovative strategy targeting mitochondria for improving health and resistance of newly weaned piglets, decreasing the needs for antibiotics in swine production and improving food safety.

Professional activities / interests

- Oxidative stress

- Mitochondrial energy metabolism

- Nutrigenomics

- Alternative to antibiotics and heavy metals in swine production

Education and awards

- B. Sc. Biology, Université Laval, 1998.

- Certificate in genetic engeneering, Université Laval, 1998.

- M. Sc. Molecular and cellular biology, Université Laval, 2001.

- Ph. D. physiology-endocrinology, Université Laval, 2005.

- Postdoctorate, Biology, Université McGill, 2011.

International experience and/or work

- Deputy Editor, British Journal of Nutrition, Cambridge University Press.

Key publications

For a complete list of publications, please visit: AAFC Online

2017

2015

2014

2011

2010

2009

Other science related publications

2016

  • Lapointe, J., Roy, C., Beaudry, D., Bergeron, N., Blanchet, I., Petit, H.V., and Palin, M.F. (2016) Effect of flax meal supplementation on oxidative stress and metabolic status of early lactation dairy cows infused with flax oil in the abomasum. Journal of Animal Science Vol. 94, E-Suppl. 5/Journal of Dairy Science Vol. 99, E-Suppl. 1. p. 684. (Abstract 1410) doi:10.2527/jam2016-1410
  • Lo Verso, L., Matte, J.J., Talbot, G., Bissonnette, N., Lapointe, J., Gagnon, N., Ouattara, B., Guay, F., and Lessard, M. (2016). "Effects of different sources and routes of administration of copper and vitamins A and D on gut volatile fatty acids and gene expression involved in regulation of innate and acquired immunity in piglets.", Journal of Animal Science, 94(Supp. 2). (Abstract)
  • Talbot, G., Lessard, M., Yergeau, E., Gagnon, N., Lo Verso, L., Lapointe, J., Bissonnette, N., Bueno Dalto, D., Ouattara, B., Guay, F., and Matte, J.J. (2016). "Effects of different sources and routes of administration of copper and vitamins A and D on piglets gut microbiota.", Journal of Animal Science, 94(Supp. 2). (Abstract)
  • Talbot, G., Lessard, M., Yergeau, E., Gagnon, N., Lo Verso, L., Lapointe, J., Bissonnette, N., Bueno Dalto, D., Ouattara, B., Guay, F., and Matte, J.J. (2016). "Microbiota of the small intestine of piglets affected by perinatal administration of copper and vitamins A and D.", 18th International Conference on Microbiota Buenos Engineering, Buenos Aires, Argentina, 27-28 October, 2016.

2015

  • Lapointe, J., Roy, C.S., Bergeron, N., Lavoie, M., Beaudry, D., Blanchet, I., Petit, H.V., and Palin, M.-F. (2015). "Negative energy balance is associated with inflammatory and oxidative stress conditions in early lactation dairy cows.", Society for Free Radical Biology and Medicine’s (SFRBM) Annual Meeting, Boston, MS, USA, November 18-21, 2015.

2014

  • Lessard, M., Deschêne, K., Savard, C., Gagnon, A.-È., Lapointe, J., Pinilla, V.A., Guay, F., and Chorfi, Y. (2014). "Effect of deoxynivalenol (DON) ingestion on expression of genes involved in intestinal barrier and immune functions.", 7ième Symposium du CRIPA, Hyacinthe, Québec, Canada, 3-4 juin 2014, Présentation orale.
  • Lessard, M., Deschêne, K., Savard, C., Lapointe, J., Guay, F., and Chorfi, Y. (2014). "Effect of deoxynivalenol (DON) ingestion on expression of genes involved in intestinal integrity and immune response.", 2014 ADSA-ASAS Midwest Meeting, Iowa Events Center, Des Moines, Iowa, USA, March 17-19, 2014, # 163; Oral Présentation. (Abstract)
  • Morisette, B., Lessard, M., Yergeau, E., Lapointe, J., Guay, F., Bissonnette, N., Matte, J.J., Letellier, A., Quessy, S., Bergeron, N., Beaulieu, C., and Talbot, G. (2014). "Influence of Feed Additives as an Alternative to Antibiotics on Gut Microbiota of Weaned Piglets Infected with Salmonella Typhimurium.", 114th General Meeting of the American Society for Microbiology, Boston, Massachusetts, USA, May 17-20, 2014.
  • Morisette, B., Lessard, M.-H., Yergeau, E., Lapointe, J., Guay, F., Bissonnette, N., Matte, J.J., Letellier, A., Quessy, S., Bergeron, N., Beaulieu, C., and Talbot, G. (2014). "Influence of Feed Additives as an Alternative to Antibiotics on Gut Microbiota of Weaned Piglets Infected with Salmonella Typhimurium.", 114th General Meeting of the American Society for Microbiology, Boston, Massachusetts, USA, May 17-20, 2014. (Abstract)
  • Morissette, B., Lessard, M., Yergeau, E., Lapointe, J., Guay, F., Bissonnette, N., Matte, J.J., Letellier, A., Quessy, S., Bergeron, N., and Talbot, B.G. (2014). "Influence of Feed Additives as an Alternative to Antibiotics on Gut Microbiota of Weaned Piglets Infected with Salmonella Typhimurium.", 7ième Symposium du CRIPA, Hyacinthe, Québec, Canada, 3-4 juin 2014. (Poster)

2013

  • Lapointe, J. (2013). "Improving sows longevity by using targeted nutritional interventions.", 49th Annual Eastern Nutrition Conference of the Animal Nutrition Association of Canada (ANAC), Hôtel Château Laurier, Québec City, QC, Canada, May 15-16, 2013, pp. 119-136.

2012

  • Lapointe, J. (2012). "Improving productivity and longevity of livestock by using a nutrigenomics approach targeting mitochondrial energy metabolism and oxidative stress status.", AAFC Scientific Symposium: Let’s talk science at DSRDC, Sherbrooke, QC, Canada, November 28, 2012.
  • Lapointe, J. and Palin, M.-F. (2012). "Nutrigenomics: What? Why? and What’s in it for me?", 30th Anniversary Jefo Symposium, Saint-Hyacinthe, QC, Canada, August 29, 2012. (Presentation)
  • Lapointe, J., Roy, M., Audet, I., Beaudry, D., Palin, M.-F., Quesnel, H., Guay, F., and Matte, J.J. (2012). "Organic selenium and vitamin B6 synergize to up-regulate glutathione peroxidases (GPx) expression in dietary supplemented gilts.", Society for the Study of Reproduction 45th Annual Meeting and 18th Ovarian Workshop, Pennsylvania State University, State College, PA, USA, August 12-15, 2012, Abs. 469. (Abstract)
  • Van Calsteren, M.-R., Gagnon, F., Lapointe, J., Guertin, N., and LaPointe, G. (2012). "Structure determination of the exopolysaccharide produced by Lactococcus lactis subsp. Cremoris strain JFR1.", MOOT XXV Mini NMR Symposium, Université Laval, Québec City, QC, Canada, October 20-21, 2012.

Novais, A. K., Martel-Kennes, Y., Deschene, K., Roy, C., Bergeron, N., Laforest, J-P., Lessard, M., Matte, J.J. and Lapointe, J. 2019. Tissue-specific profiling reveals modulation of cellular and mitochondrial oxidative stress in normal and low birth weight piglets throughout the peri-weaning period. Animal. 25:1-11.

Lapointe, J. Improving Health and Resistance of Animals in Swine and Dairy Production by Using an Innovative Nutritional Strategy Targeting Mitochondria.  Booklet of the 1st Animal Nutrition Conference of Canada (ANAC). May 10-11th, Quebec City, Canada. p. 196-212.

Roy, C., Lavoie, M., Richard, G., Archambault, A. and Lapointe, J. 2016. Evidence that oxidative stress is higher in replacement gilts than in multiparous sows. Journal of Animal Physiology and Animal Nutrition 100(5):911-9.

Lapointe, J. 2014. Mitochondria as promising targets for nutritional interventions aiming to improve performance and longevity of sows. Journal of Animal Physiology and Animal Nutrition 98 (5):809-821.

Affiliations

- Adjuct professor, Biology, Université de Sherbrooke.

- Adjunct professor, Animal Science, Université Laval.

 

Language

English
French