Graham van Aggelen

Manager - Manager of Pacific Enviornmental Science Centre-Pacific and Yukon Lab for Env Testing (PYLET)Management of the aquatic toxicological staff and toxicological science conducted in the laboratory
Environment and Climate Change Canada

Current research and/or projects

Delivery of aquatic toxicological services to the Water Science and Technology Directorate and the Enforcement program

  • Development of in-house toxicogenomic capacity and expertise using Salmonids; Strategic Technologies for Advancement of Genomics in Environment (STAGE)
  • Toxicogenomic evaluation of emerging chemicals of concern in municipal waste water entering the Georgia basin
  • Toxicogenomic evaluation of priority chemicals under Chemical Management Plan; application of toxicogenomic tools to determine potential EDC gene related profiles
  • Development of in-house toxicogenomic capacity and expertise using Amphibians

Education and awards

Bachelor of Science-Zoology

Environment Canada Citation of Excellence for Toxicogenomics-2005

Key publications

Wiseman, S., H. Osachoff, E. Bassett, J. Malhotra, J. Bruno, G. van Aggelen, T.P. Mommsen and M.M. Vijayan. 2007. Gene expression pattern in the liver during recovery from an acute stressor in rainbow trout. Comp. Biochem. Physiol. D 2(3): 234-244.

Tyler, C.R., A. Filby, T. Iguchi, V. Kramer, D.G.J. Larsson, G. van Aggelen, C. van Leeuwen, M. Viant, D. Tillitt. 2006. Application of Genomics to Tiered Testing. In: Molecular Biology and Risk Assessment: Evaluation of the Potential Roles of Genomics in Regulatory Ecotoxicology (ed. Ankley G). Society of Environmental Toxicology and Chemistry. (In press).

Wiseman, S., H. Osachoff, E. Bassett, J. Malhotra, J. Bruno, G. VanAggelen, T.P. Mommsen and M.M. Vijayan. 2007. Gene expression pattern in the liver during recovery from an acute stressor in rainbow trout. Comp. Biochem. Physiol. D (doi:10.1016/j.cbd.2007.04.005).

Crump, D., K. Werry, N. Veldhoen, G. van Aggelen and C.C. Helbing. 2002. Exposure to the herbicide acetochlor alters thyroid hormone-dependent gene expression and metamorphosis in Xenopus Laevis. Environmental Health Perspectives. 110:1199-1205.

Expertise

Affiliations

CAEAL-Program Committee Member

EEM Science Committee Member