Frank You

Image Frank You
Research Scientist

Research in genomics and bioinformatics of crops, especially wheat and flax. Primarily working on plant bioinformatics, quantitative genetics and statistical genomics, genome sequencing, genome evolution, and software tool and database development

Current research and/or projects

  • Genetic and epigenetic variants of Canadian cereal crops for breeding and functional analysis; GRDI project.

  • Integrated genomics, plant pathology and breeding research for improvement of Fusarium Head Blight resistance in Canadian cereals; WGRF project.

  • Characterization of rust resistance genes of flax; ADF project.

  • Early-maturing dry bean variety and germplasm development for Manitoba and Western Canada; CAP pulse cluster.

  • Pre-breeding platform for Canadian wheat improvement; CAP wheat cluster.

  • Genomics and molecular markers to identify resistance genes in flax; CAP project.

  • 4DWheat: diversity, domestication, discovery and delivery; Genome Canada and AAFC project.

  • Targeted and useful genomics for barley and oat; AAFC project.

 

Research and/or project statements

  • Development of a new generation of flax refeence genome.
  • QTL identification and gene mining for the traits of inportance, especially seed yield and disease resistance in flax and wheat.
  • Development of a genomic selection strategy to maximize prediction accuracy and reducing selection cost through minimizing the number of markers.
  • Development of bioinfomatics tools amd databases to facilitate analysis of a large amount of genomic and phenotypic data and gene mining.

Education and awards

  • Ph.D. Plant Genetics and Breeding (Statistical Genetics), Nanjing Agricultural University, 1989
  • MSc Plant Genetics and Breeding (Statistical Genetics), Nanjing Agricultural University, 1985
  • BSc Computer Science, University of Manitoba, 1999
  • BSc Agronomy, Sichuan Agricultural University, 1982

Key publications

  1. Fatima F, McCallum B, Hiebert C, McCartney C, Fedak G, Pozniak C, Edwards T, Ravichandran S, You FM, Cloutier S (2020) Single and multi-locus genome-wide association study for leaf rust resistance in cultivated, progenitor and wild wheat. Proc 28th Plant and Animal Genome Conference, San Diego, USA, Jan 11-15, PO0937

    2020 - View publication details

  2. Cloutier S, You FM, Soto-Cerda BJ (2019) Linum Genetic Markers, Maps and QTL Discovery. In: Genetics and Genomics of Linum, Plant Genetics and Genomics: Crops and Models 23, Cullis CA (ed), Springer Nature, Switzerland, Chap 7, doi.org/10.1007/978-3-030-23964-0_7

    2019 - View publication details

  3. You FM, Cloutier S (2019) Assembly of the Flax Genome into Chromosomes. In: Genetics and Genomics of Linum, Plant Genetics and Genomics: Crops and Models 23, Cullis CA (ed), Springer Nature, Switzerland, Chap 5, doi.org/10.1007/978-3-030-23964-0_5

    2019 - View publication details

  4. Fatima F, Edwards T, Hiebert C, McCartney C, McCallum B, Henriquez MA, Humphreys G, Cao W, Fedak G, You FM, Cloutier S (2019) Diversity analysis of wheat and wild relatives using the wheat 90K Infinium array. Proc 1st International Wheat Congress, Saskatoon, July 21-27, P217 (poster)

    2019 - View publication details

  5. Young LW, Trouve J-P, Speck A, Kutcher R, Rashid KY, You FM, Cloutier S and Booker HM. Mapping rust and powdery mildew resistant genes in flax. XXVII Plant and Animal Genome Conference, San Diego, USA, January 12-16, 2019 (PO0871).

    2019 - View publication details

  6. Jia G, You FM, Cloutier S, Deyholos MK, and Booker H. The flax breeding database (FlaxDB). XXVII Plant and Animal Genome Conference, San Diego, USA, January 12-16, 2019. PE1082

    2019 - View publication details

  7. Bruskiewich RM, Caron CT, Kucheran LS, Jia G, Young LW, Staton SE, Légaré J-S, Wang Z, Huellas-Bruskiewicz K, Warfield A, Marden E, Bett K, Booker HM, Cloutier S, You FM and Rieseberg LH. The DivSeek Canada Initiative: out of the starting gate. XXVII Plant and Animal Genome Conference, San Diego, USA, January 12-16, 2019 (PO0035)

    2019 - View publication details

  8. Soto-Cerda, B.J., Cloutier, S., Quian, R., Gajardo, H.A., Olivos, M., You, F.M. (2018). Genome-wide association analysis of mucilage and hull content in flax (Linum usitatissimum l.) seeds, 19(10), http://dx.doi.org/10.3390/ijms19102870

    2018 - View publication details

  9. You, F.M., Xiao, J., Li, P., Yao, Z., Jia, G., He, L., Kumar, S., Soto-Cerda, B., Duguid, S.D., Booker, H.M., Rashid, K.Y., Cloutier, S. (2018). Genome-wide association study and selection signatures detect genomic regions associated with seed yield and oil quality in flax, 19(8), http://dx.doi.org/10.3390/ijms19082303

    2018 - View publication details

  10. Sandhu, K.S., You, F.M., Conner, R.L., Balasubramanian, P.M., Hou, A. (2018). Genetic analysis and QTL mapping of the seed hardness trait in a black common bean (Phaseolus vulgaris) recombinant inbred line (RIL) population, 38(3), http://dx.doi.org/10.1007/s11032-018-0789-y

    2018 - View publication details

  11. You FM, Rashid K, Cloutier S, Chen W, Luo M-C, Zhu (2018) High-quality genome sequences of cultivated (Linum usitatissimum) and wild (L. bienne) flax. Proc 26th Plant and Animal Genome Conference, San Diego, CA, January 13-17, P0911 (poster)

    2018 - View publication details

  12. Zhu S, Wang L, You FM, Rodriguez JC, Deal KR, Chen L, Li J, Chakraborty S, Balan B, Jiang CZ, Brown PJ, Leslie CA, Aradhya M, Dandekar AM, Kluepfel DA, Dvorak J, LuoM-C (2017) A novel and efficient approach for phasing highly heterozygous plant genomes. Proc 26th Plant & Animal Genome Conference, San Diego, CA, January 13-17, P0193 (poster)

    2018 - View publication details

  13. Jorden M, You FM (2018) Improved markers for a pre-harvest sprouting QTL on wheat chromosome 3B. Proc 26th Plant and Animal Genome Conference, San Diego, CA, January 13-17, P1042 (poster)

    2018 - View publication details

  14. Luo, M.C., Gu, Y.Q., Puiu, D., Wang, H., Twardziok, S.O., Deal, K.R., Huo, N., Zhu, T., Wang, L., Wang, Y., McGuire, P.E., Liu, S., Long, H., Ramasamy, R.K., Rodriguez, J.C., Van Sonny, L., Yuan, L., Wang, Z., Xia, Z., Xiao, L., Anderson, O.D., Ouyang, S., Liang, Y., Zimin, A.V., Pertea, G., Qi, P., Bennetzen, J.L., Dai, X., Dawson, M.W., Müller, H.G., Kugler, K., Rivarola-Duarte, L., Spannagl, M., Mayer, K.F.X., Lu, F.H., Bevan, M.W., Leroy, P., Li, P., You, F.M., Sun, Q., Liu, Z., Lyons, E., Wicker, T., Salzberg, S.L., Devos, K.M., Dvoák, J. (2017). Genome sequence of the progenitor of the wheat D genome Aegilops tauschii, 551(7681), 498-502. http://dx.doi.org/10.1038/nature24486

    2017 - View publication details

  15. You, F.M., Jia, G., Xiao, J., Duguid, S.D., Rashid, K.Y., Booker, H.M., Cloutier, S. (2017). Genetic variability of 27 traits in a core collection of flax (Linum usitatissimum L.), 8 http://dx.doi.org/10.3389/fpls.2017.01636

    2017 - View publication details

  16. Sandhu K, You FM, Conner R, Balasubramanian P, Hou A (2018) QTL mapping of seed hardness trait in common bean (Phaseolus vulgaris). Joint Annual Meeting of Canadian Phytopathological Society and Canadian Society of Agronomy, Winnipeg, MB, June 18-22 (poster).

    2017 - View publication details

  17. Ravichandran S, You FM, Rashid KY, Young L, Booker HM, Cloutier S (2017) Structural organization and haplotypes of rust resistance genes in flax. Joint Meeting Canadian Phytopathological Society and Canadian Society of Agronomy, Winnipeg, June 18-22, P3 (poster)

    2017 - View publication details

  18. You FM, Rashid K, Yao Z, Cloutier S (2017) Genome-wide association study for Fusarium wilt resistance in flax (Linum usitatissimum L.). Joint Meeting of Canadian Phytopathological Society and Canadian Society of Agronomy, Winnipeg, MB, June 18-22 (poster).

    2017 - View publication details

  19. Ren, J., Chen, L., Jin, X., Zhang, M., You, F.M., Wang, J., Frenkel, V., Yin, X., Nevo, E., Sun, D., Luo, M.C., Peng, J. (2017). Solar radiation-associated adaptive SNP genetic differentiation in wild emmer wheat, Triticum dicoccoides, 8 http://dx.doi.org/10.3389/fpls.2017.00258

    2017 - View publication details

  20. Muñoz-Amatriaín, M., Mirebrahim, H., Xu, P., Wanamaker, S.I., Luo, M.C., Alhakami, H., Alpert, M., Atokple, I., Batieno, B.J., Boukar, O., Bozdag, S., Cisse, N., Drabo, I., Ehlers, J.D., Farmer, A., Fatokun, C., Gu, Y.Q., Guo, Y.N., Huynh, B.L., Jackson, S.A., Kusi, F., Lawley, C.T., Lucas, M.R., Ma, Y., Timko, M.P., Wu, J., You, F., Barkley, N.A., Roberts, P.A., Lonardi, S., Close, T.J. (2017). Genome resources for climate-resilient cowpea, an essential crop for food security, 89(5), 1042-1054. http://dx.doi.org/10.1111/tpj.13404

    2017 - View publication details

Research facility

960 Carling Avenue
Ottawa, ON K1A 0C6
Canada

Affiliations

Guest professor of Nanjing Agricultural University

Adjunct professor of University of Manitoba

Language

English

Other languages

Mandarin/Chinese