Dr. Wayne Xu
1. Lead a bioinformatics team for Bioinformatics Research Support
2. Research in genomics and bioinformatics for genome, transcriptome, proteomics, epigentics, genomic variations, gene regulation, trait associtation studies.
Current research and/or projects
- Targeted and useful genomics for barley and oat (TUGOAT): funded (2019-2024) by Agriculture and Agri-Food Canada (AAFC) project J-002373 in partnership with Génome Québec and the National Barley Cluster led by the Barley Council of Canada (BCC) through the Canadian Agriculture Partnership (CAP).
- Crop Rotation Affects Disease Suppressive Soil Microbiomes: funded (2021-2023) by Ag Action Manitoba Program – Research and Innovation.
Research and/or project statements
- Genome assembly: Using Illumina paired-end reads, long mate-pair reads, PacBio sequences, 10X chromium linked read libraries, and chromosome conformation capture sequencing (Hi-C) to assemble genome to chromosome pseudomolecules.
- Transcriptome differentiation studies: using RNA-seq for transcriptome differentiation analyses
- Genomic variation studies: using whole genome sequencing (WGS), genotype-by-sequencing (GBS), and whole exome capture (WEC) sequencing to analyze SNPs/INDELs.
- Genome-wise association study (GWAS): Developing AI learning models for wheat and barley GWAS to aid in genomic selection (GS) and genomic edit (GE).
- Microbiome: Using whole genome sequencing or 16S sequencing for microbiota and microbiome studies.
- Gene functional analysis and annotation: Using database and computational tools for gene, protein, and genome annotations.
Professional activities / interests
- Bioinformatics
- Journal review
- Grant review
- Teaching
Education and awards
- Ph.D. Microbiology and Immunology, Nanjing Agricultural University and Shanghai Institute of Biochemistry, CAS.
- BSc. Computer Science, University of Manitoba
Key publications
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J. R. Tucker, A. Badea, W. G. Legge, S. Maiti, Z. Yao, W. Xu, and W.G. D. Fernando. 2020. Transcriptomic analysis of a low-DON, in vitro selected, two-row malting barley variety in response to infection by multiple chemotypes of Fusarium graminearum. 2020 National Fusarium Head Blight Forum, December 2020, virtual. Poster#36.
2020 - View publication details
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Rampitsch M, Huang M, Zhen Y, Radovanovic N, Xu W, Rampitsch C, Bykova NV (2019). Profiling of histone acetylation and methylation marks associated with embryo and aleurone tissue-specific epigenetic regulation of seed dormancy in wheat. ASMS Conference on Mass Spectrometry and Allied Topics. Atlanta, Georgia, June 2 - 6, 2019. Poster presentation, Abstract ID number: 299846.
2019 - View publication details