Dr. Shiliang Liu
Applied Research Division & Maternal, Child and Youth Health Division, Centre for Surveillance and Applied Research
Current research and/or projects
Dr. Liu’s primary research interests are perinatal epidemiology, maternal and child health, specifically, fetal and early childhood development. He also focuses on promoting perinatal health and preventing congenital anomalies through research and surveillance activities. His lab produces new evidence in support of core public health priorities.
Research and/or project statements
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Assessing the impact of COVID-19 pandemic on maternal and child health, and the burden on the health care system
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Advancing the Government's efforts to carry out maternal mortality and severe maternal morbidity surveillance with innovate approaches
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Quantify the associations between maternal characteristics, conditions and prenatal factors and serious congenital anomalies in the offspring
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Elucidate the paradox in perinatology through demonstrating the heterogeneity of, and prevent preterm and low birthweight infants
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Strengthen the public health intervention policy of fortification of flour and pasta with folic acid to prevent congenital anomalies such as neural tube defects and critical congenital heart disease
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Evaluate the INTERGROWTH-21st Project fetal and newborn standard for use in Canada
Professional activities / interests
Supervises graduate students and young professionals
Invited to seminars in Canada and internationally
Peer review for Canada Research Chairs (CRC) Program and Canadian Institutes of Health Research (CIHI) funding and training programs
Education and awards
Education
Certificate, Reproductive & Perinatal Epidemiology, University of Michigan, USA, 2005
DipPH, Chronic Disease Prevention & Control, National Institutes of Health, USA, 1996
PhD, Epidemiology, Tongji Medical University, China, 1993
MSc, Health Statistics, Tongji Medical University, China, 1988
MB (Doctor of Medicine equivalent), Hengyang Medical College, China, 1983
Awards
CIHR grant of $100,000 for a project aimed at adapting new international fetal and newborn growth standards (Intergrowth-21st Project) for use in Canada {2017-2020}
CIHR grant of 1,150,000 for a project aimed at enhancing Canadian perinatal care regionalization through systems approach (with a team of researchers across Canada) {2017-2022}
International experience and/or work
International panels on universal food fortification intervention and the public health policy, and Healthy Mothers and Healthy Babies.
Teach neonatologists at the International Training Program in Neonatal-Perinatal Medicine
Advisor to the Director of the WHO-Shanghai Collaborative Centre for Statistics on Maternal and Child Health, Shanghai, China
Guest Professor, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China
Additional links
Key publications
Wei, S. Q., Bilodeau-Bertrand, M., Liu S., Auger, N. The impact of COVID-19 on pregnancy outcomes: a systematic review and meta-analysis. CMAJ 2021 April 19;193:E540-8. doi: 10.1503/cmaj.202604; early-released March 19, 2021
Boutin, A., Lisonkova, S., Muraca, G., Razaz, N., Liu, S., Kramer M.S, Joseph, K. S., Bias in comparisons of mortality among very preterm births. PloS ONE, published June 30, 2021
https://doi.org/10.1371/journal.pone.0253931
Liu, S., Evans, J., Boutin, A., Luo, W., Gheorghe, M., Auger, N., Laura, A., Moore, A., Joseph, K.S., Little, J., Time trends, geographic variation and risk factors for gastroschisis in Canada, 2006 to 2017. Paediatr Perinat Epidemiol. 2021; 35(6): 664-73.DOI: 10.1111/ppe.12800.
Liu, S., Dzakpasu, S., Nelson, C., Wei, SQ., Little, J., Scott H., Joseph, KS. Pregnancy outcomes during the COVID-19 pandemic in Canada, March to August 2020. J Obstet Gynaecol Can 2021;12:1406-15. https://doi.org/10.1016/j.jogc.2021.06.014
Yong, S.Y., Liu, S. Proposed subtypes of post-COVID-19 syndrome (or long-COVID) and their respective potential therapies. Rev Med Virol. 2021; e2315: https: doi:10.1002/rmv.2315
Bakker, MK., Bergman, JEH., Krikov, S., Amar, E., Cocchi, G., Cragan, J., de Walle, HEK., Gatt, M., Groisman. B., Liu S, et al. Prenatal diagnosis and prevalence of critical congenital heart defects: An international retrospective cohort study BMJ Open 9:e028139.
http://doi.org/10.1136/bmjopen-2018-028139
Dzakpasu S, Deb-Rinker P, Arbour L, Darling EK, Kramer MS, Liu S, Luo W, Murphy P, Nelson C, Ray JG, Scott H, VandenHof M, Joseph KS. Severe maternal morbidity in Canada: Temporal trends and regional variations, 2003-2016. J Obstet Gynaecol Can. 2019 May 3. pii: S1701-2163(19)30089-1.
http://doi.org/10.1016/j.jogc.2019.02.014
Muraca, G.M, Liu, S, Sabr, Y., Lisonkova, S., Skoll, A., Brant, R, Cundiff, G.W., Stephansson. O., Razaz, N., Joseph, K.S. Episiotomy use among vaginal deliveries and the association with anal sphincter injury: a population-based retrospective cohort study. CMAJ 2019; October 21, 191:E1149-58.
http://doi.org/10.1503/cmaj.190366
Liu, S., Pan, Y., Auger, N., Sun, W., Li, S., Xie, S., Wen, S.W., Chen, D.J., Small head circumference at birth: a multiyear liveborn cohort study in China. BMJ Paediatrics Open 3:e000470.
http://doi.org/10.1136/bmjpo-2019-000470
Dzakpasu S, Deb-Rinker P, Arbour L, Darling EK, Kramer MS, Liu S, et al. Severe maternal morbidity surveillance: Monitoring pregnant women at high risk for prolonged hospitalisation and death. Paediatr. Perinat. Epidemiol. 2019 Aug 12.
http://doi.org/10.1111/ppe.12574
Liu, S., Evans J., MacFarlane, A., Ananth CV., Little J., Kramer MS., Joseph KS. Association of maternal risk factors with the recent rise of neural tube defects in Canada. Pediatric and Perinatal Epidemiology 2019;
http://doi.org/10.1111/PPE.12543
Liu S, Chan WS, Ray JG, Kramer MS, Joseph KS. Stroke and cerebrovascular disease in pregnancy: incidence, temporal trends, and risk factors. Stroke 2018;50:13-20.
Chaillet, N., Bujold, E., Masse. B., Liu, S., et al. A cluster-randomized trial to reduce major perinatal morbidity among women with one prior caesarean delivery in Québec (PRISMA trial): study protocol for a randomized controlled trial. Trials 18.
http://doi.org/10.1186/s13063-017-2150-x
Li, D., Chen, Y., Sun W., Liu, S. Association between hypertensive disorders during pregnancy and the subsequent risk of end-stage renal disease: a population-based follow-up study. J Obstet Gynaecol Can 2018;40(9): 1129-1137.
Contact
Research facility
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Affiliations
Adjunct Professor, School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa
Adjunct Professor, Faculty of Graduate Studies and Postdoctoral Research, University of Ottawa
Adjunct Professor, Maternal-Fetal Medicine, Research Institute of Obstetrics & Gynecology, Third Affiliated Hospital, GuangZhou Medical University, GuangZhou, China