Dr. Shiliang Liu

Senior Research Scientist

Applied Research Division/Maternal, Child and Youth Health Division, Centre for Surveillance and Applied Research

Current research and/or projects

Dr. Liu’s primary research interests are perinatal epidemiology, maternal and child health, specifically, fetal and early childhood development. He also focuses on promoting perinatal health and preventing congenital anomalies through research and surveillance activities. His lab produces new evidence in support of core public health priorities.

Research and/or project statements

  • Advancing the Government's efforts to carry out maternal mortality and severe maternal morbidity surveillance with innovate approaches

  • Quantify the associations between maternal characteristics, conditions and prenatal factors and serious congenital anomalies in the offspring

  • Elucidate the paradox in perinatology through demonstrating the heterogeneity of, and prevent preterm and low birthweight infants

  • Strengthen the public health intervention policy of fortification of flour and pasta with folic acid to prevent congenital anomalies such as neural tube defects and critical congenital heart disease

  • Evaluate the INTERGROWTH-21st Project fetal and newborn standard for use in Canada

Professional activities / interests

Supervises graduate students and young professionals

Invited to seminars in Canada and internationally

Peer review for Canada Research Chairs (CRC) Program and Canadian Institutes of Health Research (CIHI) funding and training programs

Education and awards

Education

Certificate, Reproductive & Perinatal Epidemiology, University of Michigan, USA, 2005

DipPH, Chronic Disease Prevention & Control, National Institutes of Health, USA, 1996

PhD, Epidemiology, Tongji Medical University, China, 1993

MSc, Health Statistics, Tongji Medical University, China, 1988

MB (Doctor of Medicine equivalent), Hengyang Medical College, China, 1983

Awards

CIHR grant of $100,000 for a project aimed at adapting new international fetal and newborn growth standards (Intergrowth-21st Project) for use in Canada {2017-2020}

CIHR grant of 1,150,000 for a project aimed at enhancing Canadian perinatal care regionalization through systems approach (with a team of researchers across Canada) {2017-2022}

International experience and/or work

International panels on universal food fortification intervention and the public health policy, and Healthy Mothers and Healthy Babies.

Teach neonatologists at the International Training Program in Neonatal-Perinatal Medicine

Advisor to the Director of the WHO-Shanghai Collaborative Centre for Statistics on Maternal and Child Health, Shanghai, China

Guest Professor, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China

Key publications

Bakker, MK., Bergman, JEH., Krikov, S., Amar, E., Cocchi, G., Cragan, J., de Walle, HEK., Gatt, M., Groisman. B., Liu S, et al. Prenatal diagnosis and prevalence of critical congenital heart defects: An international retrospective cohort study BMJ Open 9:e028139.

http://doi.org/10.1136/bmjopen-2018-028139

Dzakpasu S, Deb-Rinker P, Arbour L, Darling EK, Kramer MS, Liu S, Luo W, Murphy P, Nelson C, Ray JG, Scott H, VandenHof M, Joseph KS. Severe maternal morbidity in Canada: Temporal trends and regional variations, 2003-2016. J Obstet Gynaecol Can. 2019 May 3. pii: S1701-2163(19)30089-1.

http://doi.org/10.1016/j.jogc.2019.02.014

Muraca, G.M, Liu, S, Sabr, Y., Lisonkova, S., Skoll, A., Brant, R, Cundiff, G.W., Stephansson. O., Razaz, N., Joseph, K.S. Episiotomy use among vaginal deliveries and the association with anal sphincter injury: a population-based retrospective cohort study. CMAJ 2019; October 21, 191:E1149-58.

http://doi.org/10.1503/cmaj.190366

Liu, S., Pan, Y., Auger, N., Sun, W., Li, S., Xie, S., Wen, S.W., Chen, D.J., Small head circumference at birth: a multiyear liveborn cohort study in China. BMJ Paediatrics Open 3:e000470.

http://doi.org/10.1136/bmjpo-2019-000470

Dzakpasu S, Deb-Rinker P, Arbour L, Darling EK, Kramer MS, Liu S, et al. Severe maternal morbidity surveillance: Monitoring pregnant women at high risk for prolonged hospitalisation and death. Paediatr. Perinat. Epidemiol. 2019 Aug 12.

http://doi.org/10.1111/ppe.12574

Liu, S., Evans J., MacFarlane, A., Ananth CV., Little J., Kramer MS., Joseph KS. Association of maternal risk factors with the recent rise of neural tube defects in Canada. Pediatric and Perinatal Epidemiology 2019;

http://doi.org/10.1111/PPE.12543

Liu S, Chan WS, Ray JG, Kramer MS, Joseph KS. Stroke and cerebrovascular disease in pregnancy: incidence, temporal trends, and risk factors. Stroke 2018;50:13-20.

Chaillet, N., Bujold, E., Masse. B., Liu, S., et al. A cluster-randomized trial to reduce major perinatal morbidity among women with one prior caesarean delivery in Québec (PRISMA trial): study protocol for a randomized controlled trial. Trials 18.

http://doi.org/10.1186/s13063-017-2150-x

Sun, W., Lin, Y., Liu, S., Chen, Y.H., Chen, J.J, Wen, S.W., Chen, D., Comparison of maternal and neonatal outcomes for patients with placenta accrete spectrum between Online-to-Offline management model with standard care model.  Euro J Obstet and Gynecol & Repro Biol 222; 161-165. 

https://doi.org/10.1016/j.ejogrb.2018.01.035

Li, D., Chen, Y., Sun W., Liu, S. Association between hypertensive disorders during pregnancy and the subsequent risk of end-stage renal disease: a population-based follow-up study.  J Obstet Gynaecol Can 2018;40(9): 1129-1137.

https://doi.org/10.1016/j.jogc.2018.01.022

Research facility

1015 Arlington Street
Winnipeg, MB R3E 3M4
Canada

Affiliations

Adjunct Professor, School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa

Adjunct Professor, Faculty of Graduate Studies and Postdoctoral Research, University of Ottawa

Adjunct Professor, Maternal-Fetal Medicine, Research Institute of Obstetrics & Gynecology, Third Affiliated Hospital, GuangZhou Medical University, GuangZhou, China

Language

English

Other languages

Chinese