Dr. Nancy Ames

Image Nancy Ames
Research Scientist

To examine the bioactive components in cereal grains (barley, oat, wheat, and others) and pulses, and their impact on human health; to determine the effect of processing on functionality and health benefits of grain and pulse based foods. 

Agriculture and Agri-Food Canada

Current research and/or projects

Investigating the effect of pre-harvest glyphosate on quality of milling oats.

Evaluating the effect of processing methods, genotype and environment on the extractability of protein from oats and characterizing physiochemical and nutritional attributes of oat protein.

Investigating the effect of heat treatment on the storage stability, functional properties and sensory and microbial quality of food grade canaryseed groats and flours.

Determining levels of free asparagine (a precursor for acrylamide formation in baked foods) in Canadian Western Red Spring wheat varieties, and to identify effective mechanisms for its reduction.

Research and/or project statements

  • goal is to work in conjunction with breeders, researchers and the agri-food industry to develop improved cultivars and food processing techniques that maximize the health properties and utilization potential of Canadian grains and pulses
  • research experiments include:
    • quantification and characterization of fibre, phenolics and other compounds
    • pilot scale processing such as flaking, heat treatments and fractionation
    • functional food formulation for quality assessment and design of clinical trial test foods
    • development of in vitro methods for predicting and validating health outcomes.
  • Dr. Ames’ research program provides an important link between consumer health interests, industry development of value-added agricultural products, and genetic resources for Canadian-grown grains and pulses (fork to farm).

Professional activities / interests

Definition of Whole Grains Committee - member

AAFC Women in Science - chair

Human Research Ethics Committee - chair

AAFC Ethics Committe - chair

Oat Quality Evaluation Team - member

Prairie Recommending Committee - member

Prairie Grain Development Committee - member

Healthy Grains Institute - scientific advisory board member

Quaker Oats Center of Excellence - scientific advisory board member

Verna J. Kirkness science education program - planning committee member

 

 

Education and awards

Education

1989    Doctor of Philosophy, Department of Agriculture-Crop Science, University of Guelph, Supervised by Dr. Bert Christie. PhD thesis: “Variability among strains and field isolates of Rhizobium leguminosarum biovar trifolii as measured on red clover (Trifolium pratense L.)”.

1982    Master of Science, Department of Plant Science, University of Manitoba, supervised by Dr. Ken Clarke and Dr. Anna Storgaard

1980    Bachelor of Science, Department of Food Science, University of Manitoba

Awards

2018    Recipient of Agriculture and Agri-Food Canada’s Prize for Outstanding Achievement in Science

2016    Mentor of the year award in recognition of outstanding contributions to the Sanofi-Aventis BioTalent Challenge.       

2015    American Association of Cereal Chemists International Edith Christensen Award.

2012    Accuracy Award for Analysis of Dietary Fiber, for the most accurate and precise results in 2011 for insoluble, soluble, total dietary fiber and beta-glucan.

2012    Recognition of Analytical Performance in Analysis of Dietary Fiber, with an "Outstanding Accuracy and Precision" rating for 2011 for insoluble, soluble, total dietary fiber and beta-glucan.

2010    AAFC Instant Award for achieving the Guinness world record for the biggest bowl of oatmeal, and the success of the 2010 CIFST-AAFC Conference and AAFC Food Network Meeting.

2010    Guinness World Record for the biggest bowl of oatmeal.

2008    American Association of Cereal Chemists International Accuracy Award for Dietary Fiber Analysis.

2008    American Association of Cereal Chemists International Certificate of Proficiency for Dietary Fiber Analysis.

2007-2008      Biotech Challenge Mentor of the year-Distinction, Aventis Biotech Challenge CANADA

Key publications

For a complete list of publications, please visit: AAFC Online

 

Ames, N., Salimi Khorshidi, A., Joseph (Thandapilly), S., Cuthbert, R. (2019) Application of low-intensity ultrasound as a rapid, cost-effective tool to wheat screening: Discrimination of Canadian varieties at 10 MHz. Journal of Cereal Science. In Press.

Ndou, S.P., Kiarie, E., Walsh, M.C., Ames, N., de Lange, C.F.M., Nyachoti, C.M. (2018). Interactive effects of dietary fibre and lipid types modulate gastrointestinal flows and apparent digestibility of fatty acids in growing pigs. British Journal of Nutrition. doi.org/10.1017/S0007114518003434

Kock, L., Brummer, Y., Exley, T., Rhymer, C., Storsley, J., Xie, K., Chu, Y., Ou, B., Ames, N., Tosh, S., Bordenave, N.  (2018). In vitro assessment of oat beta-glucans nutritional properties: An inter-laboratory methodology evaluation. Carbohydrate Polymers. 200:271-277. https://doi.org/10.1016/j.carbpol.2018.07.082

Malunga, L.N., Thandapilly, S.J., Ames, N. (2018). Cereal derived phenolic acids and intestinal alpha glucosidase activity inhibition: Structural activity relationship. Journal of Food Biochemistry. DOI: 10.1111/jfbc.12635

Salimi Khorshidi, A., Storsley, J., Malunga, L, Joseph, S., Ames, N. (2018). Advancing the science of wheat quality evaluation using nuclear magnetic resonance (NMR) and ultrasound based techniques. Cereal Chemistry. DOI: 10.1002/cche.10040

Thandapilly, S.J., Wang, Y., Ndou, S.P., Nyachoti,C.M., Ames, N.P. (2018). Barley β-glucan increases fecal bile acid excretion and short chain fatty acid levels in mildly hypercholesterolemic individuals. Journal of Food and Function. 2018, DOI: 10.1039/C8FO00157J

Salimi Khorshidi, A., Thandapilly, S.J., Ames, N. (2018). Application of low-intensity ultrasound as a rapid, cost-effective tool to wheat screening: A systematic frequency selection. Journal of Cereal Science. 82:190–197. https://doi.org/10.1016/j.jcs.2018.06.011

Salimi Khorshidi, A., Storsley, J., Malunga, L Joseph, S., Ames, N. (2018). Advancing the science of wheat quality evaluation using nuclear magnetic resonance (NMR) and ultrasound based techniques. Cereal Chemistry. 95:347-364. DOI: 10.1002/cche.10040

Wang, Y., Harding, S.V., Thandapilly, S.J., Tosh, S.M., Jones, P.J.H., Ames, N. (2017). Barley β-glucan reduces blood cholesterol levels via interrupting bile acid metabolism. British Journal of Nutrition. 118:822–829. doi:10.1017/S0007114517002835

Ndou, S.P., Kiarie, E., Thandapilly, S.J., Walsh, M.C., Ames, N., Nyachoti, C.M. (2017). Flaxseed meal and oat hulls supplementation modulates growth performance, blood lipids, intestinal fermentation, bile acids, and neutral sterols in growing pigs fed corn–soybean meal–based diets. Journal of Animal Science. 95:3068–3078. doi:10.2527/jas2016.1328

Cuvelier, K., Storsley, J., Mollard, R., Thandapilly, S.J., Ames, N. (2017). A review of the impact of whole pulses on glycemic response. Cereal Foods World. 62(2):53-58.

Boyd, L, Holley, R., Storsley, J., Ames, N. (2017). Effect of heat treatments on microbial load and properties of beta-glucan present in whole grain barley. Cereal Chemistry. 94(2):333-340. http://dx.doi.org/10.1094/CCHEM-04-16-0099-R

Boyd, L., Storsley, J., Ames, N. (2017). Effect of heat treatments on starch pasting, particle size and color of whole grain barley. Cereal Chemistry. 94(2):325-332. http://dx.doi.org/10.1094/CCHEM-04-16-0100-R 

AbuMweis, S., Joseph Thandapilly, S., Storsley, J., Ames, N. (2016). Effect of barley beta--glucan on postprandial glycemic response in the healthy human population: a meta-analysis of randomized controlled trials. Journal of Functional Foods. 27:329–342. 

Wang, Y., Harding, S.V., Eck, P., Thandapilly, S.J., Gamel, T.H., Abdel-Aal, E-S.M., Crow, G.H., Tosh, S.M., Jones, P.J.H., and Ames, N.P. (2016). High-Molecular-Weight β-Glucan Decreases Serum Cholesterol Differentially Based on the CYP7A1 rs3808607 Polymorphism in Mildly Hypercholesterolemic Adults., Journal of Nutrition, 146(4), pp. 720-727. doi : 10.3945/jn.115.223206 

Wang, Y., Ames, N.P., Tun, H.M., Jones, P.J., Khafipour, E.  (2016). High molecular weight barley beta-glucan alters gut microbiota toward reduced cardiovascular disease risk. Frontiers in Microbiology, February 10, 2016 | doi: 10.3389/fmicb.2016.00129  

Wang, X., Storsley, J., Thandapilly, S., Ames, N.  (2016). Effects of Processing, Cultivar, and Environment on the Physicochemical Properties of Oat Beta-Glucan. Cereal Chemistry, 93(4):402-408. http://cerealchemistry.aaccnet.org/doi/pdf/10.1094/CCHEM-12-15-0245-R 

AbuMweis, S., Joseph Thandapilly, S., Storsley, J., Ames, N. (2016). Effect of barley beta--glucan on postprandial glycemic response in the healthy human population: a meta-analysis of randomized controlled trials. Journal of Functional Foods. 27:329–342. 

Ames, N., Storsley, J., Joseph Thandapilly, S. (2016). Development of new methods to assess the nutritional aspects of cereal grain products. Cereal Foods World, Sept/October 2016, volume 61(5), 184-187. http://dx.doi.org/10.1094/CFW-61-5-0184

Ramprasath, V.R., Thandapilly, S.J., Yang, S., Abraham, A., Jones, P. J. H., Ames, N. 2015.  Effect of consuming novel foods consisting high oleic canola oil, barley β-glucan, and DHA on cardiovascular disease risk in humans: the CONFIDENCE (Canola Oil and Fibre with DHA Enhanced) study – protocol for a randomized controlled trial. Trials. 16:489. DOI 10.1186/s13063-015-1014-5

Ames, N., Storsley, J. (2015). Mini Review: Effects of barley on post-prandial glycemic response. Diabesity v. 1(3); p. 21-23. http://dx.doi.org/10.15562/diabesity.2015.15

Ames, N., Blewett, H., Storsley, J., Thandapilly, S.J., Zahradka, P., and Taylor, C. (2015). A double-blind randomized controlled trial testing the effect of a barley product containing varying amounts and types of fibre on the postprandial glucose response of healthy volunteers. British Journal of Nutrition. 113(9):1373-83. doi: 10.1017/S0007114515000367

Ames, N., Storsley, J., Tosh, S. (2015). Effects of processing on physiochemical properties and efficacy of beta-glucan from oat and barley. Cereal Foods World. 60(1): 4-8, http://dx.doi.org/10.1094/CFW-60-1-0004

Gamel, T.H., Abdel-Aal, E.M., Ames, N.P., Henderson, K., Prothon, F., Kongraksawch, T., and Tosh, S.M. (2015). AACC approved methods technical committee report: a new AACCI approved method (32-24.01) for measuring viscosity of beta-glucan in cereal products using the Rapid Visco Analyzer. Cereal Foods World, 60(6): 279-283.

Gamel, T.H, Abdel-Aal, E.M., Ames, N.P., Duss R., and Tosh, S.M. (2014). Enzymatic extraction of beta-glucan from oat bran cereals and oat crackers and optimization of viscosity measurement. Journal of Cereal Science. 59(1): 33-40, doi: 10.1016/j.jcs.2013.10.011 

May, W.E., Ames, N., Irvine, R.B., Kutcher, H.R., Lafond, G.P., Shirtliffe, S.J. (2014) Crown rust in oats: when are fungicide applications to control crown rust of economic benefit to producers? Canadian Journal of Plant Science, 94(5), pp. 911-922. doi : 10.4141/CJPS2013-333  

Nayak, B.N., Rempel, C.B., Pascoe, D., Ames, N., and Fulcher, R.G. (2013). Immune modifiers from selected prairie crops: concentration effects of mixed linkage (1→3, 1→4) beta-glucans and saskatoon berry extracts on TNFα expression and cell growth in RAW 264.7 cells. Journal of Nutrition and Food Science. 3(6): 1-7, doi: 10.4172/2155-9600.1000232

Harding, S.V., Storsley, J., Thandapilly, S.J., Ames, N. (2013). Lower 30 minute serum insulin in healthy Sprague-Dawley rats consuming chips from specific barley flour blends. Cereal Chem., 90 (5): 474-479. http://dx.doi.org/10.1094/CCHEM-08-12-0099-R

Mitchell Fetch, J.W., Tekauz, A., Brown, P.D., Ames, N., Chong, J., Fetch Jr., T.G., Haber, S.M., Menzies, J.G., Townley-Smith, T.F., Stadnyk, K.D., Green, D.A. (2013). Stride Oat. Canadian Journal of Plant Science, 93: 1-5.

Gamel, T.H., Abdel-Aal, E-S.M., Wood, P.J., Ames, N.P., and Tosh, S.M. (2012). Application of the rapid Visco Analyzer (RVA) as an effective rheological tool for measurement of β-glucan viscosity. Cereal Chemistry, 89(1), pp. 52-58. doi: 10.1094/CCHEM-07-11-0089

Gliwa, J., Gunenc, A., Ames, N.P., Willmore, W.G., and Hosseinian, F.S. (2011). Antioxidant activity of alkylresorcinols from rye bran and their protective effects on cell viability of PC-12 AC cells., Journal of Agricultural and Food Chemistry, 59(21), pp. 11473-11482. doi: 10.1021/jf2023353

Yan, W., Mitchell Fetch, J.W., Frégeau-Reid, J.A., Rossnagel, B.G., and Ames, N.P. (2011). Genotype × Location Interaction Patterns and Testing Strategies for Oat in the Canadian Prairies., Crop Science, 51(5), pp. 1903-1914. doi: 10.2135/cropsci2010.09.0548

AbuMweis, S.S., Jew, S., and Ames, N.P. (2010). β-glucan from barley and its lipid-lowering capacity: a meta-analysis of randomized, controlled trials., European Journal of Clinical Nutrition, 64(12), pp. 1472-1480. doi: 10.1038/ejcn.2010.178

Mitchell Fetch, J.W., Brown, P.D., Ames, N.P., Chong, J., Fetch Jr., T.G., Haber, S.M., Menzies, J.G., Townley-Smith, L., and Stadnyk, K.D. (2011). Stainless oat., Canadian Journal of Plant Science, 91(2), pp. 357-361. doi: 10.4141/CJPS10159

Mitchell Fetch, J.W., Brown, P.D., Ames, N.P., Chong, J., Fetch Jr., T.G., Haber, S.M., Menzies, J.G., and Stadnyk, K.D. (2011). Summit oat., Canadian Journal of Plant Science, 91(4), pp. 787-791. doi: 10.4141/CJPS10158

Clarke, F.R., Clarke, J.M., Ames, N.P., and Knox, R.E. (2010). Gluten index compared to SDS-sedimentation volume for early generation selection for gluten strength in durum wheat., Canadian Journal of Plant Science, 90(1), pp. 1-11. doi: 10.4141/CJPS09035

Mitchell Fetch, J.W., Brown, P.D., Duguid, S.D., Ames, N.P., Chong, J., Fetch Jr., T.G., Haber, S.M., Menzies, J.G., and Stadnyk, K.D. (2009). Jordan oat., Canadian Journal of Plant Science, 89(1), pp. 67-71. doi: 10.4141/CJPS08095

Mitchell Fetch, J.W., Kibite, S., Clayton, G.W., Turkington, T.K., Chong, J., Fetch Jr., T.G., Haber, S.M., Menzies, J.G., and Ames, N.P. (2009). Lu Oat. Canadian Journal of Plant Science, 89(4), pp. 671-675. doi: 10.4141/CJPS08193

Mitchell Fetch, J.W., Chong, J., Clayton, G., Fetch, T.T.G., Haber, S., Menzies, J.J.G., Turkington, T.K., Ames, N.P. 2009. Lee Williams Hulless Oat. Canadian Journal of Plant Science. Published July 2009.

AbuMweis, S.S., Jew, S., Ames, N.P., Lee, T. 2009. Barley beta-glucan and its cholesterol lowering capacity: a meta-analysis of randomized controlled trials. Submitted to the American Journal of Clinical Nutrition.

Ames, N.P. and Rhymer, C.R. (2008). Issues Surrounding Health Claims for Barley., Journal of Nutrition, 138(Suppl. 6), pp. 1237S-1243S.

 

 

 

 

 

Affiliations

Research Scientist, Agriculture and Agri-Food Canada   

Adjunct Professor, Department of Human Nutritional Sciences, University of  Manitoba, Canada

Language

English