Dr. Michele C. Loewen

Image Michele C. Loewen
Senior Research Officer

I am a biochemist specializing in protein structure-function (interactions and engineering). I work accross a spectrum of fields focussed on the protection of Canada's agricultural crops and the value-added bioprocessing of agricultural-derived biomass.

Key publications

2019

  • Demissie ZA, Brown WG, Loewen MC. (2019). A Universally Primed-Polymerase Chain Reaction (UPPCR) Marker to Discriminate Clonostachys rosea ACM941 from Related Strains. J Fungi. 5(39)
  • Luu K, Rajagopalan N, Ching JCH, Loewen ME, Loewen MC. (2019). The malate-activated ALMT12 anion channel in the grass Brachypodium distachyon is co-activated by Ca2+/calmodulin. Journal of Biological Chemistry. 294: 6142-6156.

2018

  • Demissie ZA, Foote S, Tan Y, Loewen MC. (2018). Profiling of the transcriptomic responses of Clonostachys rosea upon treatment with Fusariumgraminearum secretome. Frontiers in Microbiology. 9(1061)
  • Loewen PC, Switala J, Wells JP, Huang F, Zara AT, Allingham JS, Loewen MC. (2018). Structure and Function of a Lignostilbene-α,β-dioxygenase orthologue from Pseudomonas brassicacearum. BMC Biochemistry. 19(8).

2017

  • Cuperlovic-Culf M, Loewen M, Rajagopalan N, Surendra A. (2017). Perspectives on the specific targeting of Fusarium graminearum for the development of alternative Head Blight treatment approaches. Plant Pathology. 66: 1391-1403.

2016

  • Choudhary P & Loewen MC. (2016). Evidence for a role for S. cerevisiae alpha-arrestin Art1 (Ldb19) in mating projection and zygote formations.Cell Biol Int. 40: 83-90.
  • Rajagopalan N, Nelson KM, Douglas AF, Jheequt V, Alacorn IQ, McKenna SA, Surpin M, Loewen MC1, Abrams SR. 1.corresponding author. (2016). Abscisic Acid Analogues That Act as Universal or Selective Antagonists of Phytohormone Receptors.Biochemistry. 55: 5155-5164.
  • Gordon C, Rajagopalan N, Riseeuw E, Surpin M, Ball F, Barber C, Buhrow, LM, Clark SM, Page, JE, Todd, CD, Abrams SR, Loewen MC. (2016). Identification of T. aestivum abscisic acid receptors and evidence of their role in Fusarium Head Blight.PLoS One. 11: e0164996.
  • Cuperlovich-Culf M, Rajagopalan N, Tulpan D, Loewen MC. (2016). Metabolomics and Cheminformatics analysis of Antifungal Function of Plant Metabolites.Metabolites. 6(4): E31.
  • Choudhary P & Loewen MC. (2016). Quantification of mutation-derived bias for alternate mating functionalities of the Saccharomyces cerevisiae Ste2p pheromone receptor.J Biochem. 159: 49-58.
  • Buhrow LM, Cram D, Tulpan D, Foroud NA, Loewen MC. (2016). Exogenous abscisic acid and gibberellic acid elicit opposing effects on Fusarium graminearum infection in wheat.. Phytopathology. 106: 186-196.
  • Rajagopalan N, Halasz A, Lu Y, Liu E, Monteil-Rivera F, Loewen MC. (2016). Probing allocrite preferences of two naturally occurring variants of the wheat LR34 ABC transporter.Biochem and Cell Biol.94: 459-470.
  • Panwar,V.,McCallum,B.,Jordan,M.,Loewen,M.,Fobert,P.,McCartney,C.,Bakkeren,G. (2016). RNA Silencing Approaches for Identifying Pathogenicity and Virulence ElementsTowards Engineering Crop Resistance To Plant Pathogenic Fungi.CAB Reviews. 11(027): 1-13.
  • Buhrow LM, Clark SM, Loewen MC. (2016). Identification of an attenuated barley stripe mosaic virus for the virus-induced gene silencing of pathogenesis-related wheat genes. Plant Methods. 12: 12.

 

Research facility

100 Sussex Drive
Ottawa, ON K1N 5A2
Canada

Affiliations

Adjunct Professor, Queen's University, Department of Biomedical and Molecular Sciences. Link

Adjunct Professor, University of Ottawa, Department of Chemistry and Biomolecular Sciences.Link

 

 

 

Language

English