Dr. Jian Wang, Ph.D

Research Scientist, Head of Research and Development Unit

Lead and plan research on analysis of chemical contaminants including pesticides and veterinary drugs in food using emerging mass spectrometric technologies.

Canadian Food Inspection Agency

Current research and/or projects

  1. UHPLC/ESI Q-Orbitrap and UHPLC/ESI QTRAP 6500+ plus SelexION DMS applications for target and non-target analyses of
    • Pesticide residues in fruits, vegetables, infant food, tea, grains, pulses, juices etc.
    • Veterinary drug residues in milk, eggs, and honey.
  2. Estimation of measurement uncertainty (statistics and SAS programing).

Research and/or project statements

Intelligent foresight to improve science and identify analytical gaps that are between current science capabilities and those required to address future threats for chemical contaminant analysis related to food safety mandate, and implementation of emerging technologies to safeguard Canadian food supply.

Professional activities / interests

  1. Member of the Canadian delegation to the Codex Committee on Pesticide Residues (CCPR)
  2. Member of AOAC International Technical Programming Council
  3. Member of the Joint FAO/WHO Expert Committee on Food Additives and Contaminants (JECFA)

Education and awards

EDUCATION

  1. Ph. D., Food Chemistry, Food Science and Technology, University of Alberta, Edmonton, Alberta, Canada, 2000.
  2. M. Sc., Cereal Chemistry, Grain Science, Henan University of Technology, Zhenzhou, Henan, P.R. China, 1989.
  3. B. Sc., Grain Science, Henan University of Technology, Zhengzhou, Henan, P.R. China, 1986.

AWARDS

  1. CFIA President's National Award for Innovation and Best Practices, 2017.
  2. AOAC INTERNATIONAL Expert Review Panel (ERP) of the Year, 2015.
  3. CFIA Science Branch Recognition Award for leading method development on melamine investigation, 2007.

International experience and/or work

  1. Research collaborations with US FDA, ThermoFisher Scientific and universities.
  2. Codex working groups on guidelines of method performance for analysis of pesticides and veterinary drug residues in food.

Key publications

Papers:

  1. Wang, J.; Chow, W.; Chang, J.; Wong, J. W. Development and Validation of a Qualitative Method for Target Screening of 448 Pesticide Residues in Fruits and Vegetables Using UHPLC/ESI Q-Orbitrap Based on Data-Independent Acquisition and Compound Database. J. Agric. Food Chem. 2017, 65: 473-493.
  2. Wang, J.; Cheung, W.; Chow, W., UHPLC/ESI-MS/MS determination of 187 pesticides in wine. J. AOAC Int. 2016, 99, 539-557.
  3. Wang, J.; Leung, D.; Chow, W.; Chang, J.; Wong, J. W., Development and validation of a multiclass method for analysis of veterinary drug residues in milk using ultrahigh performance liquid chromatography electrospray ionization quadrupole Orbitrap mass spectrometry. J. Agric. Food Chem. 2015, 63, 9175-9187.
  4. Yang, P.; Chang, J.; Wong, J.; Zhang, K.; Krynitsky, A.; Bromirski, M.; Wang, J. Effect of sample dilution on matrix effects in pesticide analysis of several matrices by liquid chromatography- high resolution mass spectrometry. J. Agri. Food Chem. 2015, 63, 5169-5177.
  5. Wang, J.; Cheung, W.; Chang, J.; Wong, J. W., Ultrahigh-performance liquid chromatography electrospray ionization Q-Orbitrap mass spectrometry for the analysis of 451 pesticide residues in fruits and vegetables: method development and validation. J. Agri. Food Chem. 2014, 62, 10375-10391.
  6. Wang, J.; Cheung, W.; Leung, D., Determination of pesticide residue transfer rates (percent) from dried tea leaves to brewed tea. J. Agri. Food Chem. 2014, 62, 966-983.
  7. Wang, J.; Cheung, W.; Chow, W., UHPLC/ESI-MS/MS analysis of 151 pesticides in soybeans and pulses. J. AOAC Int. 2013, 96, 1114-1133.
  8. Wang, J.; Chow, W.; Leung, D.; Chang, J., Application of ultrahigh-performance liquid chromatography and electrospray ionization quadrupole Orbitrap high-resolution mass spectrometry for determination of 166 pesticides in fruits and vegetables. J. Agric. Food Chem. 2012, 60, 12088-12104.
  9. Wang, J.; Leung, D., The challenges of developing a generic extraction procedure to analyze multi-class veterinary drug residues in milk and honey using ultra-high pressure liquid chromatography quadrupole time-of-flight mass spectrometry. Drug. Test Anal. 2012, 4, (SUPPL.1), 103-111.
  10. Wang, J.; Chow, W.; Leung, D. Applications of LC/ESI-MS/MS and UHPLC QqTOF MS for the Determination of 141 Pesticides in Tea. J. AOAC Int. 2011, 94(6), 1-30.
  11. Wang, J.; Chow, W.; Cheung, W. Application of a tandem mass spectrometer and Core-shell particle column for the determination of 151 pesticides in grains. J. Agric. Food Chem. 2011, 59, 8589-8608.
  12. Wang, J.; Chow, W.; Leung D. Applications of LC/ESI-MS/MS and UHPLC QqTOF MS for the determination of 148 pesticides in fruits and vegetables Anal. Bioanal. Chem. 2010, 396(4), 1513-1538.
  13. Wang, J.; Leung, D.; Chow, W. Applications of LC/ESI-MS/MS and UHPLC QqTOF MS for the determination of 148 pesticides in berries. J. Agric. Food Chem. 2010, 58(10), 5904-5925.
  14. Dickson, L.C.; Wang J. Analysis of residues of macrolide antibiotics in animal-derived foods. Food Eng. Ingredients. 2010, 35 (SPEC. ISSUE), 18-21.
  15. Wang, J.; Leung, D. Determination of 142 pesticides in fruit- and vegetable-based infant foods using liquid chromatography electrospray ionization tandem mass spectrometry and estimation of measurement uncertainty. J. AOAC Int. 2009, 92, 279-301.
  16. Wang, J.; Leung, D. Applications of ultra-performance liquid chromatography electrospray ionization quadrupole time-of-flight mass spectrometry on analysis of 138 pesticides in fruit- and vegetable-based infant foods. J. Agric. Food Chem. 2009, 57, 2162-2173.
  17. Wang, J.; Leung, D. Determination of spiramycin and neospiramycin antibiotic residues in raw milk using LC/ESI-MS/MS and solid-phase extraction. J. Sep. Sci. 2009, 32, 681-688.
  18. Wang, J. Analysis of macrolide Antibiotics using Liquid chromatography mass spectrometry, in food, biological and environmental matrices. Mass Spectrom. Reviews. 2009, 28, 50-92.
  19. Wang, J.; Leung, D. Analyses of macrolide antibiotic residues in eggs, raw milk, and honey using both ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry and high-performance liquid chromatography/tandem mass spectrometry. Rapid Commun. Mass Spectrom. 2007, 21, 3213-3222.
  20. Wang, J.; Wotherspoon, D. Determination of pesticides in apples using liquid chromatography electrospray ionization tandem mass spectrometry and measurement uncertainty. J. AOAC Int. 2007, 90, 55 -567.
  21. Wang, J.; Leung, D.; Lenz, S, P. Determination of five macrolide antibiotic residues in raw milk using liquid chromatography/electrospray ionization tandem mass spectrometry. J. Agric. Food Chem. 2006, 54, 2873-2880.
  22. Wang, J.; Cheung, W. Determination of pesticides in soy-based infant formula using liquid chromatography with electrospray ionization tandem mass spectrometry. J. AOAC Int. 2006, 89, 214-224.
  23. Wang, J.; Leung, D.; Butterworth, F. Determination of five macrolide antibiotic residues in eggs using liquid chromatography/electrospray ionization tandem mass spectrometry. J. Agric. Food Chem. 2005, 53, 1857-1865.
  24. Wang, J.; Cheung, W.; Grant, D. Determination of pesticides in apple-based infant foods using liquid chromatography electrospray ionization tandem mass spectrometry. J. Agric. Food Chem. 2005, 53, 528-537.
  25. Wang, J. Determination of six penicillins in honey: Confirmatory method using liquid chromatography electrospray ionization tandem mass spectrometry. J. AOAC Int. 2004, 87, 45-55.
  26. Wang, J. Determination of five macrolide antibiotic residues in honey by LC/ESI-MS and LC/ESI-MS/MS. J. Agric. Food Chem. 2004, 52, 171-181.

BOOKS:

  1. Wang, J.; MacNeil, J.; Kay, J. Editors. Chemical Analysis of Antibiotic Residues in Food. Publisher: John Wiley & Sons, Inc. 2012.
  2. Kay, J.;  MacNeil, J.; Wang, J. Editors. Chemical Analysis of Non-antimicrobial Veterinary Drug Residues in Food. Publisher: John Wiley & Sons, Inc. 2016.

BOOK CHAPTERS:

  1. Wang, J.; Turnipseed, S. Chapter 6. Chemical analysis: quantitative and confirmatory methods. In Chemical Analysis of Antibiotic Residues in Food. Publisher: John Wiley & Sons, Inc. Editors: Wang, J.; MacNeil, J.; Kay, J. 2012.
  2. Wang, J.; Cannavan, A.; Dickson, L.; Fedeniuk, R. Chapter 9. Measurement uncertainty. In Chemical Analysis of Antibiotic Residues in Food. Publisher: John Wiley & Sons, Inc. Editors: Wang, J.; MacNeil, J.; Kay, J. 2012.
  3. Wang, J. Chapter 38. Analysis of antibiotics in milk and its products. In Handbook of Dairy Foods Analysis. Publisher: CRC Press. Editors: Nollet, L.M.L.; Toldrá, F. 2010.

Affiliations

Member of AOAC International

Language

English