Dr. Jason L. McCallum

Image Jason L. McCallum
Research Scientist: Phytochemistry

Characterization of bioactive natural products from plants

  • extraction, isolation, & purification of plant bioactives
  • assay-guided fractionation of plant bioactives
  • structural characterization via LC-MS, MS-MS
  • hops, berries, small fruits, native plants
  • plant protection
  • human health

Current research and/or projects

Dr. McCallum's research program primarily focuses on improving the attributes of plants, for both food and non-food uses, in support of the horticulture and agri-food sectors.  

​Dr. McCallum characterizes phytochemical compounds in plants which may play a beneficial role in human health, or provide plants with improved performance against pests. 

Research and/or project statements

  • hops (Humulus lupulus L.) germplasm development
  • bioactives discovery from berry and small fruit crops
  • characterizing plant defensive compounds for improved plant performance
  • characterizing signalling molecules involved in plant-microbe interactions
  • characterizing phytochemical profile of native plants

Professional activities / interests

Student Mentorship/HQP training:

  • on the job training (OJT) internships
  • Co-operative Education student mentorship/supervision
  • Honour’s student mentorship/supervision
  • Graduate student mentorship/supervison

Education and awards

Education:

  • Ph.D. Plant Science, University of Guelph, Ontario Agriculture College (OAC), Department of Plant Agriculture, 2008.
  • ​B.Sc.(Hons. Co-Op) Biochemistry: Biotechnology Option, University of Waterloo, Faculty of Science, Department of Biology, 2003.

Awards:

  • NSERC PGS-D fellowship (2005-08)
  • NSERC PGS-M fellowship (2004-05)
  • OGS fellowship (2003-04)

 

 

Key publications

  1. Fofana, B., Ghose, K., McCallum, J.L., You, F.M., and Cloutier, S. (2015). "UGT74S1 is a single-copy gene and is unique In controlling Secoisolariciresinol Diglucoside (SDG) formation in flax.", Botany 2015 Joint Conference: Science and plants for people, Shaw Convention Center, Edmonton, Alberta, Canada, July 25-30, 2015. (Poster)

    2015 - View publication details

  2. Nabuurs, M.H., McCallum, J.L., and Kirby, C.W. (2014). "Isolation of Novel Pyranoanthocyanins From North American Ginseng Berry Pulp.", MOOT XXVII NMR Symposium, Montreal, QC, Canada, October 18-19, 2014. (Poster)

    2014 - View publication details

  3. Somalraju, A., Ghose, K., McCallum, J.L., and Fofana, B. (2014). "A potato without toxic compounds?/Une patate sans composés toxiques?", CLRC open House, Charlottetown, Canada, August 23, 2014. (Presentation)

    2014 - View publication details

  4. Kirby, C.W., Nabuurs, M.H., and McCallum, J.L. (2014). "Anthocyanin and Pyranoanthocyanin biosynthesis in Staghorn Sumac (Rhus typhina L.).", 52nd Annual meeting of Phytochemical Society of North America, Naleigh, NC, USA, August 9-13, 2014.

    2014 - View publication details

  5. Kirby, C.W., Nabuurs, M.H., and McCallum, J.L. (2014). "Anthocyanin and Pyranoanthocyanin biosynthesis in Staghorn Sumac (Rhus typhina L.).", 6th Maritime Natural Products Conference, Charlottetown, PEI, Canada, August 18-20, 2014.

    2014 - View publication details

  6. Kirby, C.W., Wu, T.-Y., Nabuurs, M.H., Tsao, R., Tsao, R., and McCallum, J.L. (2014). "Anthocyanin and Pyranoanthocyanin Biosynthesis in Staghorn Sumac (Rhus typhina L.).", 53rd Annual meeting of Phytochemical Society of North America (PSNA), Raleigh, North Carolina, USA, August 9-13, 2014, Presentation.

    2014 - View publication details

  7. Stetson, C.R., McCallum, J.L., and Hurta, R.A.R. (2014). "Phytochemical profiling and anti-cancer analysis of select woody plants.", AAFC Charlottetown Open House, Harrington, PEI, Canada, August 23, 2014. (Poster)

    2014 - View publication details

  8. Fischer, M.B., Nabuurs, M.H., McCallum, J.L., and Kirby, C.W. (2014). "Pyranoanthocyanin Behaviour in Solution.", MOOT XXVII NMR Symposium, Montreal, QC, Canada, October 18-19, 2014. (Poster)

    2014 - View publication details

  9. Stetson, C.R., MacPhee, J., Patel, K., McCallum, J.L., Neto, C., and Hurta, R.A.R. (2014). "Vaccinium macrocarpon flavonol-enriched extract inhibits matrix metalloproteinase-2, matrix metalloproteinase-9 and urokinase-type plasminogen activator expression in human prostate cancer cells in vitro.", Maritimes Natural Products Conference (MNPC) 2014, Charlottetown, Prince Edward Island, Canada, August 18-20, 2014.

    2014 - View publication details

  10. Nabuurs, M.H., McCallum, J.L., and Kirby, C.W. (2014). "Novel Pyranoanthocyanins Isolated From North American Ginseng Berry Pulp.", 6th Maritime Natural Products Conference, Charlottetown, PEI, Canada, August 18-20, 2014. (Presentation)

    2014 - View publication details

  11. MacPhee, J., Stetson, C.R., Elwood, B., Patel, K., McCallum, J.L., Neto, C., and Hurta, R.A.R. (2014). "Flavonol-enriched fraction from Vaccinium macrocarpon fruit inhibits matrix metalloproteinase-2, matrix metalloproteinase-9 and urokinase-type plasminogen activator expression in human prostate cancer cells in vitro.", The Journal of Functional Foods in Health and Disease, 4(11), pp. 474-492.

    2014 - View publication details

  12. Stetson, C.R., McCallum, J.L., and Hurta, R.A.R. (2014). "Phytochemical profiling and anti-cancer analysis of select woody plants.", UPEI Graduate Student Day, May 23, 2014. (Poster)

    2014 - View publication details

  13. McCallum, J.L. and Kirby, C.W. (2014). "Phytochemical profile of Staghorn sumac (Rhus typhina L) during inflorescence development.", Plant Biology 2014, Portland, Oregon, USA, July 12-16, 2014. (Poster)

    2014 - View publication details

  14. Nabuurs, M.H., McCallum, J.L., and Kirby, C.W. (2014). "Novel Pyranoanthocyanins Isolated From North American Ginseng Berry Pulp.", 6th Maritime Natural Products Conference, Charlottetown, PEI, Canada, August 18-20, 2014.

    2014 - View publication details

  15. Fofana, B., Ghose, K., McCallum, J.L., and Cloutier, S. (2014). "Flax SDG lignan glucosylation: from gene discovery to flax lines with altered SDG profiles.", Plant Biology 2014, Portland, Oregon, USA, July 12-16, 2014. (Poster)

    2014 - View publication details

  16. Kirby, C.W. and McCallum, J.L. (2014). "Temporal and tissue-specific accumulation of unusual pyranoanthocyanins during development of Staghorn sumac (Rhus typhinia L).", Plant Biology 2014, Portland, Oregon, USA, July 12-16, 2014. (Poster)

    2014 - View publication details

  17. Nabuurs, M.H., McCallum, J.L., and Kirby, C.W. (2014). "Isolation of Novel Pyranoanthocyanins From North American Ginseng Berry Pulp.", MOOT XXVII NMR Symposium, Montreal, QC, Canada, October 18-19, 2014. (Poster)

    2014 - View publication details

  18. Kirby, C.W., Wu, T.-Y., Nabuurs, M.H., Tsao, R., Tsao, R., and McCallum, J.L. (2014). "Anthocyanin and Pyranoanthocyanin Biosynthesis in Staghorn Sumac (Rhus typhina L.).", Maritimes Natural Products Conference (MNPC) 2014, Charlottetown, Prince Edward Island, Canada, August 18-20, 2014, Presentation.

    2014 - View publication details

  19. Ghose, K., McCallum, J.L., Stetson, C., and Fofana, B. (2013). "Reducing potato anti-nutritional factors.", Open House (Poster), Harington, PE, Canada, August 16, 2013. (Presentation)

    2013 - View publication details

  20. Ghose, K., Selvaraj, K., McCallum, J.L., Datla, R.S.S., Cloutier, S., and Fofana, B. (2013). "Key Catalytic Amino Acids for a Flax Secoisolariciresinol Glycosyltransferase as determined by Molecular Modeling and Site-Directed Mutagenesis.", 2013 CSPB/SCBV Annual General Meeting, Laval University, Quebec City, Canada, June 25-28, 2013.

    2013 - View publication details

Research facility

440 University Avenue
Charlottetown, PE C1A 4N6
Canada

Affiliations

 

  • Adjunct faculty: Department of Biology, University of Prince Edward Island (UPEI)
  • Adjunct faculty: Department of Graduate Studies, University of Prince Edward Island (UPEI)
  • Advisory Board: Holland College, BioScience Technology Program
  • Editorial Board: Food Research International
  • Past member: Phytochemical Society of North America

Language

English