Dr. Genevieve Labbe

Image Genevieve Labbe
Biologist

Development and implementation of bioinformatics tools and pipelines for in silico analysis of whole genome sequencing data in the Pathogen Genomics research group led by Dr. John H.E. Nash in the Division of Enteric Diseases at the National Microbiology Laboratory.

Current research and/or projects

Development of innovative genomic and bioinformatic tools for specialized laboratory testing and reference services that will contribute to more effective public health interventions.  Currently working on two research projects funded by the Genomics Research and Development Initiative (GRDI): “Single Nucleotide Variant subtyping of Salmonella Enteritidis and Salmonella Heidelberg”, and “Enteric Bacteriology: Bridging the Genomic Epidemiological Gap for priority Salmonella serovars through genomic characterization and nomenclature development”.

Research and/or project statements

 

  • Development of bioinformatics tools to support long-term surveillance of foodborne pathogens
  • Development of the biohansel tool for rapid subtyping of highly clonal pathogens using canonical Single Nucleotide Polymorphisms (SNPs).  The biohansel tool includes 33 bp k-mer SNP subtyping schemes for Salmonella enterica subsp. enterica serovar Heidelberg and Enteritidis.  https://github.com/phac-nml/biohansel

Education and awards

Doctor of Philosophy, Chemistry, University of Waterloo, Waterloo, ON.   2009

Dynamics and Inhibition of Class II Fructose 1,6-bisphosphate Aldolase

Advisor: Dr. J. Guy Guillemette

 

Master of Science, Biochemistry, Université Laval, Québec, QC.  2000

Specificity of a Hydrolase Involved in Polychlorinated Biphenyls Degradation

Advisor: Dr. Lindsay D. Eltis      

Key publications

1.            Usongo V., Berry C., Yousfi K., Doualla-Bell F., Labbé G., Johnson R., Fournier E., Nadon C., Goodridge L., Bekal S. (2018) Impact of the choice of reference genome on the ability of the core genome SNV methodology to distinguish strains of Salmonella enterica serovar Heidelberg. PLoS One. 2018 Feb 5;13(2):e0192233.

2.            Labbé G., Ziebell K., Bekal S., Macdonald K.A., Parmley E.J., Agunos A., Desruisseau A., Daignault D., Slavic D., Hoang L., Ramsay D., Pollari F., Robertson J., Nash J.H., Johnson R.P. (2016) Complete Genome Sequences of 17 Canadian Isolates of Salmonella enterica subsp. enterica Serovar Heidelberg from Human, Animal, and Food Sources. Genome Announcements 4(5):e00990-16.

3.            Labbé G., Edirmanasinghe R., Ziebell K., Nash J.H.E., Bekal S., Parmley E.J., Mulvey M.R., Johnson R.P. (2016) Complete genome and plasmid sequences of three Canadian isolates of Salmonella enterica subsp. enterica serovar Heidelberg from human and food sources. Genome Announcements 4(1):e01526-15.

4.            Rehman M.A., Labbé G., Ziebell K., Johnson R.P., Nash J.H.E. (2015) Complete Genome and Plasmid Sequences of three Canadian Strains of Salmonella enterica subsp. enterica serovar Enteritidis belonging to Phage Types 8, 13 and 13a. Genome Announcements (5):e01017-15.

Language

English
French