Dr. Eveline M. Ibeagha-Awemu

Image Eveline Ibeagha-Awemu
Research Scientist

Dr. Ibeagha-Awemu obtained a PhD in Animal Genetics from Justus Liebig University Giessen, Germany in 2003 followed by postdoctoral studies at McGill university. She joined AAFC in 2011 as a research scientist in Animal Genomics.

Her research program focuses on improving (a) productivity and disease resistance and (b) the safety of the dairy and pork value chains

Dr Ibeagha-Awemu uses next-generation sequencing/advanced technologies (e.g. genotyping-by-sequencing, high density chip genotyping, focused genotyping, whole genome sequencing, whole genome bisulphite sequencing, targeted amplicon bisulfite sequencing, etc.) to detect genetic and epigenetic markers at a genome wide scale and, gene expression (mRNA and lncRNA-Sequencing) and regulatory microRNA (miRNA-Sequencing) profiling to detect gene networks, pathways and genetic/epigenetic markers of milk production and disease (bovine mastitis and paratuberculosis) traits.

She also studies how nutrients interact with the genome and epigenome (nutrigenomics) to enhance productivity and desirable cow milk components (e.g. polyunsaturated fatty acids, cholesterol, etc.).

Another aspect of her research is focused on gut microbiota manipulation with different strategies (probiotics, fecal microbiota transplantation, etc) to stimulate early microbial establishment, immune development, improved gut health and productivity and potential to reduce antibiotics use and contamination of barn environment with pathogens.

Current research and/or projects

  • Role of DNA methylation marks in mastitis and milk production traits

  • MicroRNA biomarkers of bovine mastitis

  • Role of milk microbiota in the pathogenesis of Staphylococcus aureus mastitis

  • DNA methylation and microRNA roles in paratuberculosis

 

Professional activities / interests

  • Member: GRESABO (Groupe de Research en Sante Bovine)

  • Member: Biological Assay Committee of FAANG (Functional Annotation of Animal Genomes)

  • Member: Animal Health Committee of American Society of Animal Science/Canadian Society of Animal Science

  • Member: Op+lait grouping of researchers on milk quality through FQRNT strategic grouping program 

  • Member: Dairy Cattle Breeding and Genetics Committee, Canada

  • Member: Agriculture and Agri-Food Canada Animal Care Committee

  • Member: Canadian Bovine Mastitis Research Network

  • Editorial Board Member: BMC Genomics

  • Editorial Board Member: Scientific Reports

  • Editorial Board Member: Frontiers in Genetics

  • Past President of the Canadian Society of Animal Science 

  • Member: Canadian Society of Animal Science 

  • Member: American Dairy Science Association 

  • Member: International Society of Animal Genetics 

  • Member: International Association for Paratuberculosis  

International experience and/or work

Member: Scientific & Industrial Advisory Board of National Steering Committee of National Center for Livestock Breeding, Genetics & Genomics, Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi, Pakistan

International collaboration projects

-Mammary gland specific transcriptional profiling of Kashmiri cattle and its Jersey cross for milk quality and yield traits (India)

-Role of the microbiota in the pathogenesis of pestes des petits ruminants (Nigeria)

Key publications

  1. Ariel, O. Ibeagha-Awemu, N. Gévry, and N. Bissonnette. Johnes disease bovine monocyte-derived macrophages are insensitive to ex vivo infection by Mycobacterium avium ssp. paratuberculosis. 2016 13th International Colloquium on Paratuberculosis, Nantes, France, June 19-24th.

    2016 - View publication details

  2. Li, R., Dudemaine, P.L., Zhao, X., Lei, C., Ibeagha-Awemu, E.M. (2016). Comparative analysis of the miRNome of bovine milk fat, whey and cells. PLoS ONE, [online] 11(4), http://dx.doi.org/10.1371/journal.pone.0154129

    2016 - View publication details

  3. Ibeagha-Awemu, E.M., Li, R., Ammah, A.A., Dudemaine, P.L., Bissonnette, N., Benchaar, C., Zhao, X. (2016). Transcriptome adaptation of the bovine mammary gland to diets rich in unsaturated fatty acids shows greater impact of linseed oil over safflower oil on gene expression and metabolic pathways, 17(1), http://dx.doi.org/10.1186/s12864-016-2423-x

    2016 - View publication details

  4. Ibeagha-Awemu, E.M., Beaudoin, F., Chiquette, J., Talbot, G., Bissonnette, N., and Lessard, M. (2015). "Probiotics administration enhances calves’ lymphoproliferation responses to vaccination during the early weeks of growth.", 2015 Conference of the Canadian Society of Animal Science and the Canadian Meat Council, Ottawa, Canada, May 6-8, 2015.

    2015 - View publication details

  5. Ammah, A.A., Beaudoin, F., Marier, L., Benchaar, C., Bissonnette, N., Gévry, G., and Ibeagha-Awemu, E.M. (2015). "Effects of dietary supplementation with safflower oil on milk components and fat acid composition of Canadian Holstein cows.", 2015 Conference of the Canadian Society of Animal Science and the Canadian Meat Council, Ottawa, Canada, May 6-8, 2015.

    2015 - View publication details

  6. Ibeagha-Awemu, E.M., Li, R., Dudemaine, P.-L., Ammah, A.A., Bissonnette, N., Benchaar, C., and Zhao, X. (2015). "Mammary gland transcriptome profiling of cows fed safflower oil reveals a potential modulatory role for SREBP1 in fatty acid synthesis.", 2015 Conference of the Canadian Society of Animal Science and the Canadian Meat Council, Ottawa, Canada, May 6-8, 2015.

    2015 - View publication details

  7. Constant, E., Ibeagha-Awemu, E.M., Miglior, F., Robitaille, G., and Bissonnette, N. (2015). "Improving the genotyping-by-sequencing (GBS) approach for the identification of SNPs associated with Johne’s disease.", ADSA-ASAS JAM (Joint Annual Meeting) 2015, Orlando, Florida, USA, July 12-16, 2015, 2-15, Poster Session, pp. 651-652.

    2015 - View publication details

  8. Chiquette, J., Veilleux, L., Brochu, J., Beaudoin, F., Fomenky, B., and Ibeagha-Awemu, E.M. (2015). "Viability of the direct-fed Saccharomyces cerevisiae boulardii in the digestive tract of calves.", 2015 Conference of the Canadian Society of Animal Science and the Canadian Meat Council, Ottawa, Canada, May 6-8, 2015.

    2015 - View publication details

  9. Li, R., Dudemaine, P.-L., and Ibeagha-Awemu, E.M. (2015). "isomiR selection and cross detection will affect accurate quantification of miRNA expression.", 2015 Conference of the Canadian Society of Animal Science and the Canadian Meat Council, Ottawa, Canada, May 6-8, 2015.

    2015 - View publication details

  10. Ibeagha-Awemu, E.M., Li, R., Ammah, A.A., Bissonnette, N., Benchaar, C., and Zhao, X. (2015). "Transcriptome adaptation of the bovine mammary gland to a diet supplemented with linseed oil.", Journal of Animal Science, 93(Suppl. S3), pp. 410. (Abstract)

    2015 - View publication details

  11. Ibeagha-Awemu, E.M., Dudemaine, P.-L., Chiquette, J., Talbot, G., and Bissonnette, N. (2015). "Involvement of microRNAs in calves’ intestinal growth and development and probable modulatory role of Saccharomyces cerevisiae.", Symposium on Gut Health in Production of Food Animals, Kansas City, Missouri, USA, November 9-11, 2015. (Poster)

    2015 - View publication details

  12. Fomenky, B., Beaudoin, F., Chiquette, J., Talbot, G., Bissonnette, N., Chouinard, P.Y., Lessard, M., and Ibeagha-Awemu, E.M. (2015). "Amélioration du développement immunitaire chez les veaux laitiers par les probiotiques.", Symposium sur les bovins laitiers 2015, Drummondville, QC, Canada, Octobre 29, 2015.

    2015 - View publication details

  13. Fomenky, B., Chiquette, J., Chouinard, P.Y., and Ibeagha-Awemu, E.M. (2015). "The effect of two direct fed microbials on calf’s performance and oxidative burst capacity during the early period of growth.", 2015 Conference of the Canadian Society of Animal Science and the Canadian Meat Council, Ottawa, Canada, May 6-8, 2015.

    2015 - View publication details

  14. Ibeagha-Awemu, E.M., Li, R., and Dudemaine, P.-L. (2015). "The long non-coding RNA transcriptome of the bovine mammary gland and potential regulatory roles in fatty acid synthesis.", 6th International Symposium on Animal Functional Genomics (ISFAG), Piacenza, Italy, July 27-29, 2015, #82, pp. 91. (Abstract)

    2015 - View publication details

  15. Ariel, N., Gévry, G., Fecteau, G., Ibeagha-Awemu, E.M., Karrow, N.A., and Bissonnette, N. (2015). "Genetic association of Johne's disease susceptible cows through transcriptome profiling of MAP infected macrophages.", 2015 Conference of the Canadian Society of Animal Science and the Canadian Meat Council, Ottawa, Canada, May 6-8, 2015.

    2015 - View publication details

  16. Ibeagha-Awemu, E.M., Peters, S.O., Imumorin, I.G., and Zhao, X. (2015). "Genome-wide association study of milk protein percent in Canadian Holstein cows.", 2015 Conference of the Canadian Society of Animal Science and the Canadian Meat Council, Ottawa, Canada, May 6-8, 2015.

    2015 - View publication details

  17. Ariel, O., Gevry, N.Y., Fecteau, G., Ibeagha-Awemu, E.M., Karrow, N.A., and Bissonnette, N. (2015). "Bovine paratuberculosis monocyte-derived macrophages are insensitive to ex vivo MAP infection.", 65th Annual Canadian Society of Microbiologists Annual Conference, University of Regina, Regina, Saskatchewan, Canada, June 15-18, 2015.

    2015 - View publication details

  18. Ibeagha-Awemu, E.M., Li, R., Ammah, A.A., Bissonnette, N., Benchaar, C., and Zhao, X. (2015). "Transcriptome adaptation of the bovine mammary gland to a diet supplemented with linseed oil.", ADSA-ASAS 2015 JAM (Joint Annual Meeting), Orlando, Florida, USA, July 12-16, 2015, Invited to present at the ASAS Presidents' Picks Poster Session at JAM 2015. (Poster)

    2015 - View publication details

  19. Li, R., Beaudoin, F., Ammah, A.A., Bissonnette, N., Benchaar, C., Zhao, X., Lei, C., Ibeagha-Awemu, E.M. (2015). Deep sequencing shows microRNA involvement in bovine mammary gland adaptation to diets supplemented with linseed oil or safflower oil. BMC Genomics, [online] 16(1), http://dx.doi.org/10.1186/s12864-015-1965-7

    2015 - View publication details

  20. Ibeagha-Awemu, E.M. and Zhao, X. (2015). "Epigenetic marks: regulators of livestock phenotypes and conceivable sources of missing variation in livestock improvement programs.", Frontiers in Genetics, 6(Article 302), pp. 1-17. doi : 10.3389/fgene.2015.00302

    2015 - View publication details

Research facility

2000 College Street
Sherbrooke, QC J1M 1Z3
Canada

Affiliations

Adjunct professor: Laval university

Language

English
French