Dr. Eveline M. Ibeagha-Awemu

Image Eveline Ibeagha-Awemu
Research Scientist

Dr. Ibeagha-Awemu obtained a PhD in Animal Genetics from Justus Liebig University Giessen, Germany in 2003 followed by postdoctoral studies at McGill university. She joined AAFC in 2011 as a research scientist in Animal Genomics.

Her research program focuses on improving (a) productivity and disease resistance and (b) the safety of the dairy and pork value chains

Dr Ibeagha-Awemu uses next-generation sequencing/advanced technologies (e.g. genotyping-by-sequencing, high density chip genotyping, focused genotyping, whole genome sequencing, whole genome bisulphite sequencing, targeted amplicon bisulfite sequencing, etc.) to detect genetic and epigenetic markers at a genome wide scale and, gene expression (mRNA and lncRNA-Sequencing) and regulatory microRNA (miRNA-Sequencing) profiling to detect gene networks, pathways and genetic/epigenetic markers of milk production and disease (bovine mastitis and paratuberculosis) traits.

She also studies how nutrients interact with the genome and epigenome (nutrigenomics) to enhance productivity and desirable cow milk components (e.g. polyunsaturated fatty acids, cholesterol, etc.).

Another aspect of her research is focused on gut microbiota manipulation with different strategies (probiotics, fecal microbiota transplantation, etc) to stimulate early microbial establishment, immune development, improved gut health and productivity and potential to reduce antibiotics use and contamination of barn environment with pathogens.

Current research and/or projects

  • Role of DNA methylation marks in mastitis and milk production traits

  • MicroRNA biomarkers of bovine mastitis

  • Role of milk microbiota in the pathogenesis of Staphylococcus aureus mastitis

  • DNA methylation and microRNA roles in paratuberculosis

 

Professional activities / interests

  • Member: GRESABO (Groupe de Research en Sante Bovine)

  • Member: Biological Assay Committee of FAANG (Functional Annotation of Animal Genomes)

  • Member: Animal Health Committee of American Society of Animal Science/Canadian Society of Animal Science

  • Member: Op+lait grouping of researchers on milk quality through FQRNT strategic grouping program 

  • Member: Dairy Cattle Breeding and Genetics Committee, Canada

  • Member: Agriculture and Agri-Food Canada Animal Care Committee

  • Member: Canadian Bovine Mastitis Research Network

  • Editorial Board Member: BMC Genomics

  • Editorial Board Member: Scientific Reports

  • Editorial Board Member: Frontiers in Genetics

  • Past President of the Canadian Society of Animal Science 

  • Member: Canadian Society of Animal Science 

  • Member: American Dairy Science Association 

  • Member: International Society of Animal Genetics 

  • Member: International Association for Paratuberculosis  

International experience and/or work

Member: Scientific & Industrial Advisory Board of National Steering Committee of National Center for Livestock Breeding, Genetics & Genomics, Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi, Pakistan

International collaboration projects

-Mammary gland specific transcriptional profiling of Kashmiri cattle and its Jersey cross for milk quality and yield traits (India)

-Role of the microbiota in the pathogenesis of pestes des petits ruminants (Nigeria)

Key publications

  1. Bissonnette, N., J.-S. Brouard, O. Ariel, N. Gévry, E. Ibeagha-Awemu, and F. Miglior. 2018. Discovery of expression quantitative trait loci associated with Johne’s disease using both RNA-seq and DNA variants. 11th World Congress on Genetics Applied to Livestock Production. February 10th-16th 2018, Auckland, New-Zealand.

    2018 - View publication details

  2. Do D.N., Fomenky B.E., Dudemaine P-L., Bissonnette N. and Ibeagha-Awemu E.M. (2018) Weighted gene co-expression network analysis reveal gene clusters and pathways related to rumen development in calves. Proceedings of the 11th World Congress on Genetics Applied to Livestock Productio, 11.945, February 11 to 16, 2018, Auckland New Zealand. 5 pages.

    2018 - View publication details

  3. Ibeagha-Awemu, E.M.; Khatib, H., Chapter 29 - Epigenetics of Livestock Breeding. In Handbook of Epigenetics. The New Molecular and Medical Genetics (second edition), Edited by Tollefsbol, trygve o. Academic Press: 2017; pp 441-463.

    2017 - View publication details

  4. Brouard, J.S., Boyle, B., Ibeagha-Awemu, E.M., Bissonnette, N. (2017). Low-depth genotyping-by-sequencing (GBS) in a bovine population: Strategies to maximize the selection of high quality genotypes and the accuracy of imputation, 18(1), http://dx.doi.org/10.1186/s12863-017-0501-y

    2017 - View publication details

  5. Do, D.N., Bissonnette, N., Lacasse, P., Miglior, F., Sargolzaei, M., Zhao, X., Ibeagha-Awemu, E.M. (2017). Genome-wide association analysis and pathways enrichment for lactation persistency in Canadian Holstein cattle, 100(3), 1955-1970. http://dx.doi.org/10.3168/jds.2016-11910

    2017 - View publication details

  6. Bissonnette, N., J.-S. Brouard, B. Boyle, and E. Ibeagha-Awemu. 2017. Low-Depth Genotyping-by-Sequencing (GBS) in a Bovine Population: Strategies to Maximize the Selection of High Quality Genotypes and Accuracy of Imputation. Plant & Animal Genome Plant & Animal Genome Conference, San Diego 2017/01/14 - 2017/01/18

    2017 - View publication details

  7. Fock-Chow-Thow et al. 2017. Comparison of commercial DNA extraction kits and quantitative PCR systems for better sensitivity in detecting the causative agent of paratuberculosis in dairy cow fecal samples. Journal of Dairy Science 100(1):572-581.

    2017 - View publication details

  8. Ariel, O., Gevry, N.Y., Ibeagha-Awemu, E.M., and Bissonnette, N. (2016). "Johnes disease bovine monocyte-derived macrophages are insensitive to ex vivo infection by Mycobacterium avium ssp. Paratuberculosis.", 13th International Colloquium on Paratuberculosis, Nantes, France, 19-24 June, 2016, P-01.11, pp. 45. (Abstract)

    2016 - View publication details

  9. Do, D.N., Bissonnette, N., Lacasse, P., Miglior, F., Sargolzaei, M., Zhao, X., and Ibeagha-Awemu, E.M. (2016). "Genome wide association analysis and pathways enrichment for lactation persistency in Canadian Holstein cattle.", Journal of Animal Science, 94(Supp. 2). (Abstract)

    2016 - View publication details

  10. Ibeagha-Awemu, E.M., Li, R., and Dudemaine, P.-L. (2016). "Long non-coding RNA (lncRNA) is abundantly expressed in the gastro intestinal tract of calves.", XXIV Plant and Animal Genome Conference, San Diego, USA, January 9-13, 2016, https://pag.confex.com/pag/xxiv/meetingapp.cgi/Paper/21424. (Poster)

    2016 - View publication details