Dr Charles K. Nfon, D.M.V., Ph. D.
Research Scientist, Head - Vesicular Diseases Unit/ FAO Reference Centre for foot-and-mouth disease
- Manage diagnostic and research activities on foot-and-mouth disease and other vesicular diseases of domestic animals.
- Lead activities of the FAO Reference Centre for foot-and-mouth disease and other vesicular diseases
Current research and/or projects
- Development/improvement of laboratory diagnostic assays for vesicular diseases (foot-and-mouth disease, swine vesicular disease, vesicular stomatitis, Senecavirus A)
- Evaluation of new sample matrices for diagnosis of vesicular diseases in swine
- Evaluation of emergency/improved vaccines and vaccine matching assays for foot-and-mouth disease
- Development of field deployable diagnostic tests for foot-and-mouth disease for use in Southern Africa
Education and awards
- Postdoctoral Fellow (2008-2009): Immunology Laboratory, Hepatology Section, Department of Internal Medicine, Health Sciences Centre, University of Manitoba
- Postdoctoral Fellow (2005-2008): Plum Island Animal Disease Center, Agricultural Research Service, USDA, Orient PT., NY. Immunopathogenesis of foot-and-mouth disease virus (FMDV) infection
- Ph.D (2004): Liverpool School of Tropocal Medicine, University of Liverpool, United Kingdom
- D.V.M (1999): University of Ibadan, Nigeria
International experience and/or work
- Member of the Global Foot-and-Mouth Disease Research Alliance (GFRA): Represent the agency and part of the scientific committee for the 2017 GFRA conference in South Korea
- Member of the North American Foot-and-Mouth Disease Vaccine Bank technical committee and the International Strategic Vaccine Reserve Network
- Paticipate at OIE/FAO FMD Reference Laboratories Network Annual Meetings
- Research collaborations with international partners in Botswana, Australia, USA, New Zealand
- Senthilkumaran C, Yang M, Bittner H, Ambagala A, Lung O, Zimmerman J, Giménez-Lirola LG, Nfon C ( 2017): Detection of genome, antigen, and antibodies in oral fluids from pigs infected with foot-and-mouth disease virus. Can J Vet Res.
- Senthilkumaran C, Bittner H, Ambagala A, Lung O, Babiuk S, Yang M, Zimmerman J, Giménez-Lirola L G and Nfon C (2016): Use of oral fluids for detection of virus and antibodies in pigs infected with swine vesicular disease virus. Transbound Emerg Dis.
- Ambagala A, Fisher M, Goolia M, Nfon C, Lung O (2017): Field-deployable reverse transcription-insulated isothermal PCR (RT-iiPCR) assay for rapid and sensitive detection of foot-and-mouth disease virus. Transbound Emerg Dis.
- Bronsvoort M, Handel IG, Nfon CK, Sorensen KJ, Malirat V, Bergmann I, Tanya VN and Morgan KL (2016): Redefining the "carrier" state for foot-and-mouth disease from the dynamics of virus persistence in endemically affected cattle populations. Scientific Reports. 6:29059. doi: 10.1038/srep29059.
- Kittelberger R, Nfon C, Swekla K, Zhang Z, Hole K, Bittner H, Salo T, Goolia M, Embury-Hyatt C, Bueno R, Hannah M, Swainsbury R, O'Sullivan C, Spence R, Clough R, McFadden A, Rawdon T, Alexandersen S (2015): Foot-and-Mouth Disease in Red Deer - Experimental Infection and Test Methods Performance. Transbound Emerg Dis.
- Morgan KL, Handel IG, Tanya VN, Hamman SM, Nfon C, Bergman IE, Malirat V, Sorensen KJ, de C Bronsvoort BM (2014): Accuracy of herdsmen reporting versus serologic testing for estimating foot-and-mouth disease prevalence. Emerg Infect Dis
- Nfon C. K., Toka F. N., Kenney M., Pacheco J. and Golde W. T. (2010): Depressed plasmocytoid dendritic cell function coincides with lymphopenia and viremia during foot-and-mouth disease virus (FMDV) infection. Viral Immunology.
- Toka F. N., Nfon C. K., Dawson H. and Golde W. T. (2009): Natural killer cell dysfunction during acute infection with foot-and-mouth disease virus (FMDV). Journal of Clinical and Vaccine Immunology
- Toka F. N., Nfon C. K., Dawson H. and Golde W. T. (2009): Accessory cell mediated activation of porcine NK cells by TLR7 and TLR8 agonists. Journal of Clinical and Vaccine Immunology.
- Toka F.N., Nfon C.K., Dawson H, Mark Estes D and Golde WT (2009): Activation of Porcine Natural Killer (NK) Cells and Lysis of Foot-and-Mouth Disease Virus (FMDV) Infected Cells. Journal of Interferon and Cytokine Research.
- Nfon C. K, Dawson H, Toka F., and Golde W. (2008): Langerhans cells in porcine skin. Veterinary Immunology and Immunopathology.
- Golde W., Nfon C. K. and Toka F. N. (2008): Immune evasion during foot and mouth infection of swine. Immunological Reviews. 225(1): 85-95
- Nfon C. K, Toka F., Ferman G. and Golde W. (2008): Interferon alpha production by multiple dendritic cells is inhibited during acute infection with foot-and-mouth disease virus (FMDV). Viral Immunology
- Bronsvoort B. M., Anderson J., Corteyn P., Hamblin P., Kitching R. P., Nfon C., Tanya V. N., and Morgan K. L. (2006): Geographical and age-stratified distributions of foot-and-mouth disease virus-seropositive and probang-positive cattle herds in the Adamawa Province of Cameroon. Veterinary Record. 159(10):299-308.
- Bronsvoort B.M., Nfon C, Hamman S.M., Tanya V.N., Kitching R.P. and Morgan K.L. (2004). Risk factors for herdsman-reported foot-and-mouth disease in the Adamawa Province of Cameroon. Preventive Veterinary Medicine. 66(1-4):127-39.
- Bronsvoort B. M. de C., Radford A. D., Tanya V. N., Nfon C., Kitching R. P. and Morgan K. L. (2004). Molecular epidemiology of Foot-and-Mouth Disease viruses in the Adamawa province of Cameroon. Journal of Clinical Microbiology. 42(5):2186-96.
- Bronsvoort B M de C , Tanya V N, Kitching, R P, Nfon C, Saidou, H M, Morgan, K L. (2003) Foot and Mouth Disease and livestock husbandry practices in the Adamawa Province of Cameroon. Tropical Animal Health and Production. 35(6):491-507.
Adjunct Professor, Department of Animal Science, Faculty of Agricultural and Food Sciences, University of Manitoba, Winnipeg (Manitoba) Canada