Dr. Carissa Embury-Hyatt, DVM, MVSc, Diplomate ACVP

Head, Pathology Unit

Manage diagnostic and research activities of the pathology and electron microscopy laboratory at NCFAD. Study the pathology of emerging, zoonotic and foreign animal diseases.

Current research and/or projects

Use of pathology techniques to study the pathogenesis of diseases that are emerging or foreign to Canada such as Nipah virus, Rift Valley fever virus, influenza virus, rabbit hemorrhagic disease virus and Ebola virus. Identification of viral target cells and tissues using immunohistochemistry and in situ hybridization methods.

Professional activities / interests

Provision of instruction on foreign animal disease recognition

Education and awards

CFIA Western Awards, Leadership Award, 2017

CFIA Western Award, Collaborative Excellence Award (PEDV feed investigation), 2015

Board Certification, American College of Veterinary Pathologists, 2008

Senior Resident, Western College of Veterinary Medicine (WCVM), SK, 2004

Master of Veterinary Science, WCVM, SK, 2003

Doctor of Veterinary Medicine (with Distinction)WCVM, SK, 2001

Bachelor of Science (Honors), Major-Zoology, University of Manitoba, 1994

Key publications

Kroeker AL, Smid V, Embury-Hyatt C, Moffat E, Collignon B, Lung O, Lindsay R,
Weingartl H. RVFV Infection in Goats by Different Routes of Inoculation. Viruses.
2018 Dec 12;10(12).

Griffin BD, Muthumani K, Warner BM, Majer A, Hagan M, Audet J, Stein DR,
Ranadheera C, Racine T, De La Vega MA, Piret J, Kucas S, Tran KN, Frost KL, De
Graff C, Soule G, Scharikow L, Scott J, McTavish G, Smid V, Park YK, Maslow JN,
Sardesai NY, Kim JJ, Yao XJ, Bello A, Lindsay R, Boivin G, Booth SA, Kobasa D,
Embury-Hyatt C, Safronetz D, Weiner DB, Kobinger GP. DNA vaccination protects
mice against Zika virus-induced damage to the testes. Nat Commun. 2017 Jun

 Wong G, Qiu X, de La Vega MA, Fernando L, Wei H, Bello A, Fausther-Bovendo H,
Audet J, Kroeker A, Kozak R, Tran K, He S, Tierney K, Soule G, Moffat E, Günther
S, Gao GF, Strong J, Embury-Hyatt C, Kobinger G. Pathogenicity Comparison Between
the Kikwit and Makona Ebola Virus Variants in Rhesus Macaques. J Infect Dis. 2016
Oct 15;214(suppl 3):S281-S289.

 Berhane Y, Kobasa D, Embury-Hyatt C, Pickering B, Babiuk S, Joseph T, Bowes V,
Suderman M, Leung A, Cottam-Birt C, Hisanaga T, Pasick J. Pathobiological
Characterization of a Novel Reassortant Highly Pathogenic H5N1 Virus Isolated in
British Columbia, Canada, 2015. Sci Rep. 2016 Mar 18;6:23380.

Ranadheera C, Hagan MW, Leung A, Collignon B, Cutts T, Theriault S,
Embury-Hyatt C, Kobasa D. Reduction of Neuraminidase Activity Exacerbates Disease
in 2009 Pandemic Influenza Virus-Infected Mice. J Virol. 2016 Oct

 Kittelberger R, Nfon C, Swekla K, Zhang Z, Hole K, Bittner H, Salo T, Goolia
M, Embury-Hyatt C, Bueno R, Hannah M, Swainsbury R, O'Sullivan C, Spence R,
Clough R, McFadden A, Rawdon T, Alexandersen S. Foot-and-Mouth Disease in Red
Deer - Experimental Infection and Test Methods Performance. Transbound Emerg Dis.
2017 Feb;64(1):213-225.

 Pasick J, Berhane Y, Ojkic D, Maxie G, Embury-Hyatt C, Swekla K, Handel K,
Fairles J, Alexandersen S. Investigation into the role of potentially
contaminated feed as a source of the first-detected outbreaks of porcine epidemic
diarrhea in Canada. Transbound Emerg Dis. 2014 Oct;61(5):397-410.

Truong T, Boshra H, Embury-Hyatt C, Nfon C, Gerdts V, Tikoo S, Babiuk LA, Kara
P, Chetty T, Mather A, Wallace DB, Babiuk S. Peste des petits ruminants virus
tissue tropism and pathogenesis in sheep and goats following experimental
infection. PLoS One. 2014 Jan 30;9(1):e87145.

 Berhane Y, Embury-Hyatt C, Leith M, Kehler H, Suderman M, Pasick J.
Pre-exposing Canada Geese (Branta canadensis) to a low-pathogenic H1N1 avian
influenza virus protects them against H5N1 HPAI virus challenge. J Wildl Dis.
2014 Jan;50(1):84-97.

 Nfon CK, Leung A, Smith G, Embury-Hyatt C, Kobinger G, Weingartl HM.
Immunopathogenesis of severe acute respiratory disease in Zaire
ebolavirus-infected pigs. PLoS One. 2013 Apr 23;8(4):e61904.

 Embury-Hyatt C, Postey R, Hisanaga T, Burton L, Hooper-McGrevy K, McIntyre L,
Millar K, Pasick J. The first reported case of rabbit hemorrhagic disease in
Canada. Can Vet J. 2012 Sep;53(9):998-1002.

 Moniwa M, Embury-Hyatt C, Zhang Z, Hole K, Clavijo A, Copps J, Alexandersen
S. Experimental foot-and-mouth disease virus infection in white tailed deer. J
Comp Pathol. 2012 Aug-Oct;147(2-3):330-42.

 Embury-Hyatt C, Babiuk S, Manning L, Ganske S, Bowden TR, Boyle DB, Copps J.
Pathology and viral antigen distribution following experimental infection of
sheep and goats with capripoxvirus. J Comp Pathol. 2012 Feb-Apr;146(2-3):106-15.

 Li M, Embury-Hyatt C, Weingartl HM. Experimental inoculation study indicates
swine as a potential host for Hendra virus. Vet Res. 2010 May-Jun;41(3):33.

Embury-Hyatt CK, Wobeser G, Simko E, Woodbury MR. Investigation of a syndrome
of sudden death, splenomegaly, and small intestinal hemorrhage in farmed deer.
Can Vet J. 2005 Aug;46(8):702-8.

Research facility

1015 Arlington Street
Winnipeg, MB R3E 3M4


American College of Veterinary Pathologists

Canadian Association of Veterinary Pathologists

Manitoba Veterinary Medical Association

Canadian Veterinary Medical Association