Dr. Cam Donly

Research Scientist

Molecular biology of insects and their pathogens.

Agriculture and Agri-Food Canada

Current research and/or projects

My laboratory conducts research aimed at improving tools and practices for Canadian agriculture in three general areas: trap plant development, biopesticide development, and management of insecticide resistance.

Research and/or project statements

  • Development of insecticidal trap plants incorporating RNAi technology for insect control in greenhouse agriculture.  
  • Global analysis of gene expression of baculoviruses infecting the canola pest, bertha armyworm.
  • Characterization of molecular mechanisms involved in pesticide resistance in insects.

Education and awards

PhD, Dept of Biochemistry, University of Western Ontario

Key publications

For a complete list of publications, please visit: AAFC Online

  • Burke, W., Kaplanoglu, E., Kolotilin, I., Menassa, R., Donly, C. (2019) RNAi in the tobacco hornworm, Manduca sexta, using chloroplast-encoded long double-stranded RNA. Front. Plant Sci. 10:313. doi: 10.3389/fpls.2019.00313.
  • Kolosov, D., Donly, C., MacMillan, H., O’Donnell, M. (2019) Transcriptomic analysis of the Malpighian tubule of Trichoplusia ni: clues to mechanisms for switching from ion secretion to ion reabsorption in the distal ileac plexus. J. Insect Physiol. 112:73-89.
  • Chen, E., Kolosov, D., O’Donnell, M., Erlandson, M.A., McNeil, J.N., Donly, C. (2018) The Effect of Diet on Midgut and Resulting Changes in Infectiousness of AcMNPV Baculovirus in the Cabbage Looper, Trichoplusia ni. Front. Physiol. 9:1348 doi: 10.3389/fphys.2018.01348.
  • Kaplanoglu, E., Chapman, P., Scott, I.M., Donly, C. (2017) Overexpression of a cytochrome P450 and a UDP-glycosyltransferase is associated with imidacloprid resistance in the Colorado potato beetle, Leptinotarsa decemlineata. Scientific Reports. 7:1762.
  • Javed, M.A., Biswas, S., Willis, L.G., Harris, S., Pritchard, C., van Oers, M.M., Donly, B.C., Erlandson, M.A., Hegedus, D.D., Theilmann, D.A. (2017) AcMNPV AC83 is a PIF protein required for ODV and BV nucleocapsid assembly as well as assembly of the PIF complex in ODV envelopes. J. Virology. 91:e02115-16.
  • Donly, B.C., Kaplanoglu, E., Theilmann, D.A., Baldwin, D., Sieminska , E., Hegedus, D.D., Erlandson, M.A. (2016) MacoNPV baculovirus midgut-specific gene expression during infection of the bertha armyworm, Mamestra configurata. Virology. 499:1-8.
  • Javed, M.A., Harris, S., Willis, L.G., Theilmann, D.A., Donly, B.C., Hegedus, D.D., Erlandson, M.A. (2016) Microscopic investigation of AcMNPV infection in the Trichoplusia ni midgut. J. Invert. Pathology. 141:24-33.
  • Donly, B.C., Theilmann, D.A., Hegedus, D.D., Baldwin, D., Erlandson, M.A. (2014) Mamestra configurata nucleopolyhedrovirus-A transcriptome from infected host midgut. Virus Genes DOI 10.1007/s11262-013-0986-z 
  • Simmons J., D'Souza O., Rheault M., Donly C. (2013) Multidrug resistance protein gene expression in Trichoplusia ni caterpillars. Insect Mol Biol. 22: 62–71.
  • Lam F., McNeil J.N., Donly C. (2012) Octopamine receptor gene expression in three lepidopteran species of insect. Peptides. 41: 66-73. 
  • Labbé R., Caveney S., Donly C. (2011) Expression of multidrug resistance proteins is localized principally to the Malpighian tubules in larvae of the cabbage looper moth, Trichoplusia ni. J Exp Biol 214:937-944.
  • Labbé, R., Caveney, S., Donly, C. (2011) Genetic analysis of the xenobiotic resistance-associated ABC gene subfamilies of the Lepidoptera. Insect Mol Biol. 20:243-256. 

Affiliations

  • Adjunct Professor, Dept of Biology, University of Western Ontario
  • American Society for Virology
  • Entomological Society of Canada
  • NSERC Scholarships and Fellowships Committee 187 for Molecular and Cellular Biology

Language

English