Antoinette Ludwig

Image Antoinette Ludwig
Veterinary Epidemiologist

Research focusing on zoonotic illness

Current research and/or projects

Dr. Ludwig works with the Public Health Risk Sciences division from the Infectious Diseases Control and Prevention Branch.

Dr. Ludwig’s research focuses on identifying zoonotic disease and modelling environmental determinants of disease vectors that present a danger to public health. She specializes in modelling zoonotic vectors transmitted by insects; and works on West Nile virus and other diseases transmitted by mosquitos and ticks, notably as they relate to climate change.

Research and/or project statements

  • Scientific leadership on multiple stakeholder research projects including:

    • Modeling the combined effect of Land-Use Changes and Climate Changes on mosquito and bird biodiversity in Eastern Ontario, West Nile virus strain characterization in Eastern Canada, and Blood meal analysis of West Nile virus vectors in southern Québec

  • Scientific leadership in surveillance projects development, maintenance, data analysis and data reporting—these include:

    • scientific advisor for the provincial surveillance program for mosquito-borne diseases

    • scientific advisor for vector surveillance and modelling working group at national and international level

    • manager for data validation and analysis in the Canadian Surveillance Program for Anti-Microbial resistance

  • Research collaboration with Canadian surveillance agencies, centres, and Federal Research groups.

  • Epidemiological analysis and modelling, some examples include:

    • Modelling the geographical dispersion of Amblyomma americanum in North America according to climate changes.

    • Studying the combined effect of land use changes and climate changes on the risk of human exposure to mosquito borne diseases and mapping vulnerable human populations using remote sensing data.

    • A scoping review of mosquito determinants related to vector potential for some viruses transmitted in Canada

    • Relationship between mosquito infection and bird infection for West Nile virus and Eastern Equine Encephalitis virus in Ottawa region

    • Characterizing the Canadian West Nile virus strains diversity using the Whole Genome sequencing approach

Professional activities / interests

Supervises undergraduate, masters and PhD students

Member of NEON (National Ecological Observatory Network) Mosquito Technical Working Group

Participant in internal committees as a scientific advisor (CPHLN, Surveillance Integration Team).

Participant in an external scientific committee as scientific advisor (Québec’s advisory group for mosquito borne diseases, Observatoire multipartite québécois sur les zoonoses et l’adaptation aux changements climatiques)

Education and awards

Education

Post-Doctoral Fellow in zoonosis epidemiology and public health, University of Montreal, 2009

PhD Veterinary Science Epidemiology, Faculté de medicine veterinaries, University of Montreal, 2009

MSc Epidemiology and Biostatistics, Université Joseph Fourier, Grenoble, France, 2004

DVM Equine medicine and surgery, École Nationale Vétérinaire de Lyon (France), 2001

Grants

GRDI Funds , titre : Mosquito borne diseases surveillance by metagenomics in Canada. Chercheur principal: Nick Ogden, Total: CAN$ 578.10K pour 3 ans – début : Février 2019; participation comme chercheur collaborateur.

AAFC special funds, titre : Environmental Change One health Observatory (ECO2): A framework for  sustainable and resilient ecological goods and services for agro-ecosystems, from the microbiome to the river basin scale. Chercheur principal: David Lapen, Total: CAN$ 760K pour 3 ans – Début: Avril 2019, participation comme chercheur collaborateur

Special funds for the writing of research proposal from Institut National de Santé publique du Québec, titre : WNV outbreak determinants in southern Quebec. Chercheur principal : Antoinette Ludwig, Total : CAN$13,000.00, Avril 2015.

International experience and/or work

Expert scientifique du « Groupe expert vecteur » de l’ANSES (Agence nationale de sécurité sanitaire de l’alimentation, de l’environnement et du travail).

Collaboratrice de recherche en France (UGrenobleAlpes) et collaboration avec des centres de recherche en France (IRD, CNES).

Key publications

Allostry J, Ludwig A., Kotchi S-O, Rousseu F., Fournier R. Modélisation des densités moyennes annuelles de populations de moustiques vecteurs de maladies représentant un risque pour la santé publique dans le sud du Québec – International Journal of Health Geographics. In writing

Lowe Anne-Marie, Forest-Bérard K., Trudel R., (…) Lindsay R., Ludwig A. Using surrogate species to assess the potential entry points of invasive Aedes species mosquito (Diptera: Culicidae) in southern Québec (Canada) - Transboundary and Emerging diseases. In writing

Ludivine Taieb, Antoinette Ludwig, L. Robbin Lindsay, Mahmood Iranpour, Carl A. Gagnon, Dominique J. Bicout. Bird species involved in West Nile virus epidemiological cycle in southern, EcoHealth, Submitted

Sagurova I, Ludwig A., Ogden N., Pelcat Y., Dueymes G., Gachon P., 2019, Predicted northward expansion of the geographic range of the tick vector Amblyomma americanum in North America under future climate conditions, Environmental Health Perspectives 127 (10) CID: 107014.

https://doi.org/10.1289/EHP5668

Christian Therrien, Eric Fournier, Antoinette Ludwig, Joel Ménard, Hugues Charest, Christine Martineau, 2019, Phylogenetic analysis of West Nile virus in Quebec, Canada, 2004–2016: Co-circulation of distinct variants harbouring conserved amino acid motifs in North America. Virology 537: 65-73.

https://doi.org/10.1016/j.virol.2019.08.019

Ludwig Antoinette, Zheng Hhui, Vrbova Linda, Drebot Michael, Iranpour Mahmood, Lindsay Robbin, 2019. Increased risk of endemic mosquito-borne diseases in Canada due to climate change, Canada Communicable Disease Report 45(4) 90-97

https://doi.org/10.14745/ccdr.v45i04a03    

NH Ogden, A Ludwig, AP Morse, H Zheng, H Zhu, 2019, Weather-based forecasting of mosquito-borne disease outbreaks in Canada, Canada Communicable Disease Report 45(5): 127–132.

https://doi.org/10.14745/ccdr.v45i05a03

Kotchi SO, Bouchard C, Ludwig A, Rees EE, Brazeau S., 2019,  Using Earth observation images to inform risk assessment and mapping of climate change-related infectious diseases,  Can Commun Dis Rep, 45(5):133–42. 

https://doi.org/10.14745/ccdr.v45i05a04

Marion Ripoche, Céline Campagna, Antoinette Ludwig, Nicholas H Ogden, Patrick A Leighton. Short-term Forecasting of Daily Abundance of West Nile Virus Vectors Culex pipiens-restuans (Diptera: Culicidae) and Aedes vexans Based on Weather Conditions in Southern Québec (Canada), Journal of Medical Entomology, Volume 56, Issue 3, May 2019, p. 859–872.

https://doi.org/10.1093/jme/tjz002

Marion Ripoche*, Salima Gasmi*, Ariane Adam-Poupart, Jules K. Koffi, L. Robbin Lindsay, Antoinette Ludwig, François Milord, Nicholas H. Ogden, Karine Thivierge, Patrick A. Leighton. Passive tick surveillance provides an accurate early signal of emerging Lyme disease risk and human cases in southern Canada, 2018,  J Med Entomology, 28;55(4):1016-1026.

https://doi.org/10.1093/jme/tjy030

Affiliations

Adjunct Professor, Pathology and Microbiology Department, Faculty of Veterinary Medicine, University of Montreal

Habilitation to direct memoirs and theses, Population Medicine, Faculty of Veterinary Medicine, University of Guelph

Habilitation to direct memoirs and theses, Geomatic, Faculty of Letters and Human Sciences, University of Sherbrooke

Language

English
French