André Laroche Ph.D.

Image André Laroche
Research Scientist in Functional Genomics of Cereals

 

I am a plant molecular biologist with activities in identification of novel stripe rust resistance genes, in modification of a known defeated stripe rust resistance genes to engineer its functionality against novel isolates of stripe rust, in measuring wheat transcripts when modifying circadian clock genes in wheat toward improving its response to abiotic stresses under a climate change reality and in pyramiding a collection of different disease resistance genes in elite winter wheat germplasm using marker assisted selection.

Current research and/or projects

I use molecular genetic techniques to study plant response to fungal pathogens and to to environment, plant development and organization of plant fungal pathogens toward protecting yield of cereal crops.  

Upcycling a defeated R gene of wheat, 2019-22      

Circadian clock editing in wheat-ccWheat, 2019-23

Stomata signalling for wheat yield, 2019-23

A3GP disease forecasting, 2019-22                              

Nanocarrier technology for cereal seed treat, 2019-22

Improved Winter Wheat for Western Canada, 2018-23

Crop and Environment Interactions, 2018-21

Fungal and Bacterial Biosystematics, 2019-24

Research and/or project statements

  • Modification of known genes to improve cereal resistance against pests and abiotic stress
  • Identification of novel genes to improve cereal resistance to pathogens
  • Identification and quantification of crop pathogens using highly sensitive and specific techniques
  • Pyramiding many different disease resistance genes in elite winter wheat germplasm
  • Participating in mutlidisciplinary teams to improve diagnostic of pest impact on crops

Professional activities / interests

  • Cereal interaction with fungal pathogens
  • Cereal development and interaction with environment
  • Transcriptome analysis and gene identification of plant interactions with pathogens and environment
  • Training of undergraduate and graduate students in plant molecular genetics

 

Education and awards

Ph.D. 1987 Plant Sciences Western

M.Sc. 1983 Biology (Plant Physiology & Biochemistry) Sherbrooke

B.Sc. 1979 Biology (Physiology & Biochemistry) Sherbrooke

 

1989 - present: Wheat Molecular Geneticist, Lethbridge Research & Development Centre. Functional genomics of cereals.

 

1992 - present: Adjunct Professor, Department Of Biological Sciences (1992-1997 and 2005-present), Department Of Chemistry And Biochemistry (1997-2005), University of Lethbridge.

 

1987 - 1989: Visiting Fellow with Dr. J. Singh, Plant Research Centre, AAFC Ottawa. Molecular mechanisms of freezing tolerance in members of the Cruciferae

International experience and/or work

  • Co-supervisor of International Graduate Students

Key publications

  1. Laurie JD, Laroche A. 2021. The circadian clock in the time of changing climate: Using biotechnology to accelerate wheat adaptation. Alberta Project Leads Science Conversations Series – Climate Change Focus. February 10, 2021.

    2021 - View publication details

  2. M. Frick, G.T. Araujo, K. Fujita, D. Van Essen, C. Harvey, J.D. Laurie, R.J. Graf and A. Laroche. 2021. Remodeling the functionality of the stripe rust resistance gene Yr10 against current virulent fungal isolates. UBC-STEM Appreciation Night, January 21, 2021.

    2021 - View publication details

  3. Smith MB, Ryabova D, Roy S, Tricker P, Lawson T, Laurie J, Laroche A,*Foroud NA. Cloning a mitogen-activated protein kinase kinase kinase YODA from Triticum aestivum for transgenic expression in wheat. 41st Annual Meeting of the Plant Pathology Society of Alberta. On-line meeting, November 4-5, 2020. (Poster Presentation)

    2020 - View publication details

  4. Geddes G. 2020. Research, Review, Repeat: When farmers have questions about how to improve crop quality and yields, researchers can usually help to find the answers. Better Farming May/June Issue p.12-18.

    2020 - View publication details

  5. Laroche A, Singer S, Foroud N, Laurie J, Pittman A. 2020. Modern studies in Crop Sciences / Études Contemporaines chez les Grandes Cultures. Lethbridge AgExpo 2020, Lethbridge, AB, February 26-28, 2020.

    2020 - View publication details

  6. Laroche, André, Michele Frick. 2019. Gene expression regulation in grass, wheat and a fungal pathogen. AAFC Bioinformatics conference and workshop, September 19-20, 2019 - Lethbridge Research Development Centre, AB, Canada.

    2019 - View publication details

  7. http://www.albertawheat.com/our-programs/research/awc-funded-research

    2019 - View publication details

  8. Fujita, Kaden, Michele Frick, André Laroche. 2018. Modification of the Stripe Rust Resistance Gene Yr10 in Triticum aestivum. Proceedings of the Undergraduate Research in Science Conference of Alberta (URSCA). Vol 4 2018 Poster abstracts.

    2018 - View publication details

  9. Van Essen, Darren, Michele Frick, André Laroche. 2018. Modifying the Stripe Rust Resistance Gene Yr10 in Wheat (Triticum aestivum L.) by PCR Mutagenesis. Proceedings of the Undergraduate Research in Science Conference of Alberta (URSCA). Vol 4 2018 Poster abstracts.

    2018 - View publication details

  10. Subramaniam, G., Ouellet, T., Aboukhaddour, R., Blackwell, B., Fedak, G., Foster, A., Henriquez, M.A., Laroche, A., Larsen, J.; Miller, S., Overy, D., Rampitsch, C., Foroud, N., Schernthaner, J., Harris, L. 2017. Towards Durable Fusarium and Rust Resistance in Cereals. Wheat Science and Business Meeting, Saskatoon, November 8-9, 2017.

    2017 - View publication details

  11. Foroud NA, Goyal RK, Laroche A, Ellis BE, Tulpan D, Liu Z, Pan Y. Plant hormone and MAPK signalling pathways in wheat. Plants from Sea to Sky: 2017 Joint Meeting of the Canadian Society of Plant Biologists and the Canadian Society for Horticultural Science Vancouver. Vancouver BC, Canada, July 4-7, 2017.

    2017 - View publication details

  12. Foroud, N.A., Goyal, R.K., Chomistek, N., Gonzàlez-Peña Fundora, D., West, C., Chiu, J., Hui, L., Frick, M., Laroche, A., Ellis, B.E., and Tulpan, D. (2016). "Identification and analysis of Triticea mitogen-activated protein kinases.", 4th International Symposium on Plant Signaling and Behavior, St. Petersburg, Russia, 19-23 June, 2016. (Poster)

    2016 - View publication details

  13. Pahari, S., Cradduck, M., Eudes, F., Laroche, A., and Larsen, R.J. (2016). "Characterization of Flowering Genes in Perennial Wheatgrasses and their Relationship to Wheat.", XXIV Plant and Animal Genome Conference, San Diego, USA, January 9-13, 2016, pp. P0042.

    2016 - View publication details

  14. Tulpan, D., Léger, S., Goyal, R.K., Laroche, A., and Foroud, N.A. (2016). "Computational identification of potentially new mitogen-activated protein kinases in cereals via orthology prediction and phylogenetic analysis.", Canadian Wheat Alliance Science and Business Meeting, Saskatoon, SK, Canada, 27-29 June, 2016. (Poster)

    2016 - View publication details

  15. Araujo, G.T., Amundsen, E., Frick, M., Aboukhaddour, R., Gaudet, D.A., Selinger, B.L., Laroche, A. Stripe rust of wheat: The relationship between disease severity and spores concentration. 2nd LeRDC Graduate Symposium, Lethbridge, AB Nov 30, 2016. O, pp12.

    2016 - View publication details

  16. Goyal RK, Gonzàlez-Peña Fundora D, Vivar M, Laroche A, Tulpan D, Foroud NA. Genome-wide identification and analysis of mitogen activated protein kinases (MAPKs) in wheat. 3rd Canadian Wheat Symposium, Ottawa ON, CANADA, November 22-25, 2016. p.48

    2016 - View publication details

  17. Li, L.X., Wei, C.R., Yu, X.M., Laroche, A., Liu, D.Q. 2016. Members of hypersensitive induced reaction superfamily protein involved in wheat resistance to leaf rust. 37th Annual Meeting of the Plant Pathology Society of Alberta, Edmonton, AB, Nov 7-9, 2016. O, pp20.

    2016 - View publication details

  18. Laroche, A., Frick, M., Amundsen, E., Aboukhaddour, R., Randhawa, H., Graf, R., Larsen, J., Gaudet, D. 2016. Toward a contig reduction in genomic assembly of Puccinia striiformis f. sp. tritici isolate SWS484 (Feature Presentation). 37th Annual Meeting of the Plant Pathology Society of Alberta, Edmonton, AB, Nov 7-9, 2016. O, pp8.

    2016 - View publication details

  19. Laroche, A., Frick, M., Buckoll P., Amundsen, E., Randhawa, H., Graf, R., Gaudet, D. 2016. Regulation of gene expression in incompatible/compatible reactions between stripe rust isolates from western Canada and wheat. 13th European Conference of Fungal Genetics, April 3-6, 2016, Paris, France. CS2M84.

    2016 - View publication details

  20. Araujo, G.T., Amundsen, E., Gaudet, D., Selinger, B.L., Laroche, A. 2016. Incidence of important fungal wheat pathogens in western Canada. 50th Annual Prairie University Biology Symposium, February 18-20, 20116, University of Lethbridge, Lethbridge, AB. P1G.

    2016 - View publication details

Research facility

5403 1st Avenue South
Lethbridge, AB T1J 4B1
Canada

Affiliations

  Adjunct Professor, Department Of Biological Sciences, University of Lethbridge

Language

English
French