André Laroche Ph.D.

Image André Laroche
Research Scientist in Functional Genomics of Cereals

 

I am a plant molecular biologist with activities in identification of novel stripe rust resistance genes, in modification of a known defeated stripe rust resistance genes to engineer its functionality against novel isolates of stripe rust, in measuring wheat transcripts when modifying circadian clock genes in wheat toward improving its response to abiotic stresses under a climate change reality and in pyramiding a collection of different disease resistance genes in elite winter wheat germplasm using marker assisted selection.

Current research and/or projects

I use molecular genetic techniques to study plant response to fungal pathogens and to to environment, plant development and organization of plant fungal pathogens toward protecting yield of cereal crops.  

Upcycling a defeated R gene of wheat, 2019-22      

Circadian clock editing in wheat-ccWheat, 2019-23

Stomata signalling for wheat yield, 2019-23

A3GP disease forecasting, 2019-22                              

Nanocarrier technology for cereal seed treat, 2019-22

Improved Winter Wheat for Western Canada, 2018-23

Crop and Environment Interactions, 2018-21

Fungal and Bacterial Biosystematics, 2019-24

Research and/or project statements

  • Modification of known genes to improve cereal resistance against pests and abiotic stress
  • Identification of novel genes to improve cereal resistance to pathogens
  • Identification and quantification of crop pathogens using highly sensitive and specific techniques
  • Pyramiding many different disease resistance genes in elite winter wheat germplasm
  • Participating in mutlidisciplinary teams to improve diagnostic of pest impact on crops

Professional activities / interests

  • Cereal interaction with fungal pathogens
  • Cereal development and interaction with environment
  • Transcriptome analysis and gene identification of plant interactions with pathogens and environment
  • Training of undergraduate and graduate students in plant molecular genetics

 

Education and awards

Ph.D. 1987 Plant Sciences Western

M.Sc. 1983 Biology (Plant Physiology & Biochemistry) Sherbrooke

B.Sc. 1979 Biology (Physiology & Biochemistry) Sherbrooke

 

1989 - present: Wheat Molecular Geneticist, Lethbridge Research & Development Centre. Functional genomics of cereals.

 

1992 - present: Adjunct Professor, Department Of Biological Sciences (1992-1997 and 2005-present), Department Of Chemistry And Biochemistry (1997-2005), University of Lethbridge.

 

1987 - 1989: Visiting Fellow with Dr. J. Singh, Plant Research Centre, AAFC Ottawa. Molecular mechanisms of freezing tolerance in members of the Cruciferae

International experience and/or work

  • Co-supervisor of International Graduate Students

Key publications

  1. Laroche A. 2024. Dr. Claudia Sheedy: A Colleague, a Collaborator and a Friend. Dr. Claudia Sheedy Graduate Symposium 2024. Lethbridge Research and Development Centre. February 8, 2024.

    2024 - View publication details

  2. *Foroud NA, Abdeljalil El Habti, Stuart Roy, Younyoung Lee, Marcus Samuel, John Laurie, André Laroche, Tracy Lawson. Stomata signalling pathways for increasing yield potential in wheat. 7th Annual International Wheat Yield Partnership Conference. On-line meeting. September 27-28, 2023. Oral Presentation. Invited.

    2023 - View publication details

  3. Laurie J & Laroche A. 2023. Circadian Clock Editing to Increase Wheat Yield. 7th IWYP Program Conference. On-line meeting. September 27-28, 2023. Oral Presentation. Invited.

    2023 - View publication details

  4. Araujo, G.T., Gaudet, D.A., Amundsen, E., Frick, M., Aboukhaddour, R., Selinger, B.L., Laroche, A. (2023). Inoculum threshold for stripe rust infection in wheat. Canadian Journal of Plant Pathology, [online] 45(3), 304-319. http://dx.doi.org/10.1080/07060661.2023.2177888

    2023 - View publication details

  5. Michele Frick, Eric Amundsen, André Laroche. 2022. Distinguishing Puccinia striiformis f. sp. tritici isolates using genomic sequencing: A case study. Methods in Molecular Biology (In Press)

    2022 - View publication details

  6. Laurie J, Laroche A, Henderson I, Foroud N, Graf R, Subramaniam R, Bilichak A. 2022. In optimizing cellular processes for environmental challenges timing is everything! IWYP Science Brief #29

    2022 - View publication details

  7. Laurie J, A Laroche, I Henderson, N Foroud, R Graf, R Subramaniam, A Bilichak. 2022. In optimizing cellular processes for environmental challenges timing is everything! IWYP Science Brief #29 July 2022.

    2022 - View publication details

  8. Graf, R.J., Beres, B.L., Laroche, A., Aboukhaddour, R., Humphreys, D.G., Larsen, R.J., Randhawa, H.S., Foroud, N.A., Sidhu, H.S. (2022). AAC Coldfront hard red winter wheat. Canadian Journal of Plant Science, [online] 102(3), 785-795. http://dx.doi.org/10.1139/cjps-2022-0043

    2022 - View publication details

  9. Graf, R.J., Beres, B.L., Laroche, A., Aboukhaddour, R., Larsen, R.J., Humphreys, D.G., Randhawa, H.S., Foroud, N.A. (2022). AAC Vortex hard red winter wheat. Canadian Journal of Plant Science, [online] 102(2), 468-477. http://dx.doi.org/10.1139/cjps-2021-0142

    2022 - View publication details

  10. Laurie JD, Laroche A. 2021. COP26 Open Mic. Alberta Project Leads Science Conversations Series – Climate Change Focus. December 15, 2021.

    2021 - View publication details

  11. Harvey C, Araujo GT, Frick M, Laroche A, Laurie JD, Graf RJ, Bilichak A. A genetic approach to improve wheat resilience to emerging stripe rust isolates using novel R gene sequences from Thinopyrum intermedium. Proceedings of the 42nd Annual Meeting (Virtual) of the Plant Pathology Society of Alberta, Edmonton, AB 2021/11/04 - 2020/11/05. Oral presentation T1.

    2021 - View publication details

  12. Thirugnanasambandam I, Vucurevich T, Shelton T, Watt C, Kav N, Laroche A. Validation of polyclonal antibodies against fungal pathogens of wheat: tan spot and Fusarium head blight. Proceedings of the 42nd Annual Meeting (Virtual) of the Plant Pathology Society of Alberta, Edmonton, AB 2021/11/04 - 2020/11/05. Oral presentation S7.

    2021 - View publication details

  13. Bahrani, H., Båga, M., Larsen, J., Graf, R.J., Laroche, A., Chibbar, R.N. (2021). The relationships between plant developmental traits and winter field survival in rye (Secale cereale L.). Plants, [online] 10(11), http://dx.doi.org/10.3390/plants10112455

    2021 - View publication details

  14. Soto-Cerda B.J., Vasudevan A., Laroche A., Ragupathy R. (2022) Genome-Wide Association Studies (GWAS) in Cereals. In: Bilichak A., Laurie J.D. (eds) Accelerated Breeding of Cereal Crops. Springer Protocols Handbooks. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1526-3_4

    2021 - View publication details

  15. Frick M, Bodell K, Masic T, Harvey C, Cradduck M, Jiang F, Foroud F, Graf RJ, Laurie JD, Laroche A. 2021. The circadian clock and regulation of plant growth factors in wheat Plant Biology 2021 Worldwide Summit Virtual Meeting. Poster # 404377

    2021 - View publication details

  16. Frick M, Bodell K, Masic T, Harvey C, Cradduck M, Jiang F, Foroud F, Graf RJ, Laurie JD, Laroche A. 2021. Identification of circadian clock regulated immune response genes in wheat. Canadian Society of Plant Biologists – Société canadienne de biologie végétale 2021 Virtual Meeting. Invited Oral presentation Abstract #101

    2021 - View publication details

  17. Dhakal, S., Reiter, J.W., Laroche, A., Schultz, E.A. (2021). Leaf vein pattern response to heat and drought requires genes that influence PINFORMED1 localization and is mimicked by ABA treatment. Environmental and Experimental Botany, [online] 185 http://dx.doi.org/10.1016/j.envexpbot.2021.104426

    2021 - View publication details

  18. Rabanus-Wallace, M.T., Hackauf, B., Mascher, M., Lux, T., Wicker, T., Gundlach, H., Baez, M., Houben, A., Mayer, K.F.X., Guo, L., Poland, J., Pozniak, C.J., Walkowiak, S., Melonek, J., Praz, C.R., Schreiber, M., Budak, H., Heuberger, M., Steuernagel, B., Wulff, B., Börner, A., Byrns, B., Čížková, J., Fowler, D.B., Fritz, A., Himmelbach, A., Kaithakottil, G., Keilwagen, J., Keller, B., Konkin, D., Larsen, J., Li, Q., Myśków, B., Padmarasu, S., Rawat, N., Sesiz, U., Biyiklioglu-Kaya, S., Sharpe, A., Šimková, H., Small, I., Swarbreck, D., Toegelová, H., Tsvetkova, N., Voylokov, A.V., Vrána, J., Bauer, E., Bolibok-Bragoszewska, H., Doležel, J., Hall, A., Jia, J., Korzun, V., Laroche, A., Ma, X.F., Ordon, F., Özkan, H., Rakoczy-Trojanowska, M., Scholz, U., Schulman, A.H., Siekmann, D., Stojałowski, S., Tiwari, V.K., Spannagl, M., Stein, N. (2021). Chromosome-scale genome assembly provides insights into rye biology, evolution and agronomic potential. Nature Genetics, [online] 53(4), 564-573. http://dx.doi.org/10.1038/s41588-021-00807-0

    2021 - View publication details

  19. Thirugnanasambandam I, Vucurevich T, Shelton T, Watt C, Kav N, Laroche A. 2021. Development of a multiplex real-time immuno-PCR assay for the simultaneous detection of three wheat fungal pathogens. Fifth Annual Graduate Research Symposium (virtual) Agricultural, Life and Environmental Sciences (ALES) Graduate Students Association (GSA), University of Alberta, March 29-30, 2021. Poster

    2021 - View publication details

  20. Laurie JD, Laroche A. 2021. The circadian clock in the time of changing climate: Using biotechnology to accelerate wheat adaptation. Alberta Project Leads Science Conversations Series – Climate Change Focus. February 10, 2021.

    2021 - View publication details

Research facility

5403 1st Avenue South
Lethbridge, AB T1J 4B1
Canada

Affiliations

  Adjunct Professor, Department Of Biological Sciences, University of Lethbridge

Language

English
French