Aiming Wang, Ph.D

Image Aiming Wang
Research Scientist

My research program is directed to study the viral pathogens that threaten crop production in Canada. Extensive research has been done to identify the viral pathogens that cause devastating diseases on soybean, cereals, field horticultural crops, and greenhouse vegetables, and to better understand the infection process of the identified major viruses. Much of the research has also been concentrated on the development of genetic resistance, vaccines, and other novel technologies to control them.

Current research and/or projects

  • Development of genetic resistance to plum pox virus (PPV) in Prunus
  • Development of gentic resistance to soybean mosaic virus in soybean using genome editing technology
  • Molecular characterization of viral pathogens on horticultural crops such as greenhouse vegetables, strawberries and cherry/apple trees, and development of IPM-based strategies to control them
  • Better understanding of the virus infection process and molecular virus-host interactions for the development of novle antivral technologies.

Research and/or project statements

  • Identification of novel host factors required for virus infection
  • Identification of novel functional roles of virus-encoded proteins 
  • Novel discoveries in the co-evolutionary arms race between viruses and plant hosts
  • Identification of newly emerging viruses infecting greenhouse vegetables and field crops in Canada

Professional activities / interests

  • Understanding of molecular virus-plant interactions and virus genome expression and replication mechanism
  • Molecular isolation of host factors and natural resistance genes
  • Development of novel antiviral strategies through biotechnology and beneficial uses of plant viruses
  • Training PhD students and postdoctoral scientists

Education and awards

PhD, the University of British Columbia in 1999

Gold Harvest (Innovation and Excellence), Agriculture and Agri-Food Canada in 2010

Queen Elizabeth II Diamond Jubilee Medal, Government of Canada in 2013

Outstanding Research Award, the Canadian Phytopathological Society in 2019

Ruth Allen Award, the American Phytopathological Society in 2019

International experience and/or work

Collaborative research being carried out with colleagues in China, the United States, Spain and France

Key publications

  1. Li, F., Zhao, N., Li, Z., Xu, X., Wang, Y., Yang, X., Liu, S.S., Wang, A., Zhou, X. (2017). A calmodulin-like protein suppresses RNA silencing and promotes geminivirus infection by degrading SGS3 via the autophagy pathway in Nicotiana benthamiana, 13(2), http://dx.doi.org/10.1371/journal.ppat.1006213

    2017 - View publication details

  2. Cheng, X., Wang, A. (2017). The potyvirus silencing suppressor protein VPg mediates degradation of SGS3 via ubiquitination and autophagy pathways, 91(1), http://dx.doi.org/10.1128/JVI.01478-16

    2017 - View publication details

  3. Wang, A.M. and Cui, H.G. (2016). "The Plum pox virus 6K1 protein is required for viral replication and targets the viral replication complex at the early infection stage.", 9th European Congress of Virology, Hamburg, Germany, October 19-22, 2016.

    2016 - View publication details

  4. Wang, A.M. (2016). "Future Perspectives of Plant-Virus-Host Interactions.", 5th Fuzhou International Symposium of Plant Pathology. Fuzhou, China, August 21-23, 2016.

    2016 - View publication details

  5. Wang, A.M. (2016). "Developing Next Generation Resistance to Plant Viral Diseases.", 5th Fuzhou International Symposium of Plant Pathology, Fuzhou, China, August 21-23, 2016

    2016 - View publication details

  6. Simkovich, A., Kohalmi, S., Wang, A.M. (2016). "Small RNA Sequencing Leads to the First Report of Cherry Virus A in Ontario, Canada.", 35th Annual Meeting of the American Society for Virology, Blacksburg, Virginia June 18–22, 2016.

    2016 - View publication details

  7. Ding, X., Li, Y., Hernández-Sebastià, C., Abbasi, P.A., Fisher, P., Celletti, M., and Wang, A.M. (2016). "First Report of Strawberry crinivirus 4 on Strawberry in Canada.", Plant Disease, pp. 1-3. doi : 10.1094/PDIS-01-16-0009-PDN

    2016 - View publication details

  8. Chen, B., Cheng, X., Bernards, M., Wang, A.M. (2016) "Molecular identification and the complete genome sequence of a new Ilarvirus from pepper.", 35th Annual Meeting of the American Society for Virology, Blacksburg, Virginia June 18–22, 2016.

    2016 - View publication details

  9. Zhang, L. and Wang, A.M. (2016). "ER stress, UPR and virus infections in plants.", in Wang, A. and Zhou, X. (eds.) - Current Research Topics in Plant Virology, Springer, pp. 173-196.

    2016 - View publication details

  10. Li, Y., Zhang, C., Wang A.M. (2016). "The DEAD-box RNA helicase AtRH9 in Arabidopsis that is required for Turnip mosaic virus infection.", 35th Annual Meeting of the American Society for Virology, Blacksburg, Virginia June 18–22, 2016.

    2016 - View publication details

Research facility

1391 Sandford Street
London, ON N5V 4T3
Canada

Affiliations

  • Adjunct Professor, Department of Biology, University of Western Ontario
  • Senior Editor, Molecular Plant-Microbe Interactions (MPMI)
  • Associate Editor, PLoS Pathogenes
  • Editorial Board Member of Journal of Virology, Scientific Reports, Molecular Plant Pathology, Virology, and Soybean Science
  • Lifetime Member, American Society for Virology
  • Full Member, International Society for Molecular Plant-Microbe Interactions
  • Member of International Plum Pox Virus Scientific Committee
  • Memebr of Potyviridae Study Group, International Committee on Taxonomy on Viruses
  • Member of Bromoviridae Study Group, International Committee on Taxonomy on Viruses

Language

English