Aiming Wang, Ph.D
My research program is directed to study the viral pathogens that threaten crop production in Canada. Extensive research has been done to identify the viral pathogens that cause devastating diseases on soybean, cereals, field horticultural crops, and greenhouse vegetables, and to better understand the infection process of the identified major viruses. Much of the research has also been concentrated on the development of genetic resistance, vaccines, and other novel technologies to control them.
Current research and/or projects
- Development of genetic resistance to plum pox virus (PPV) in Prunus
- Development of gentic resistance to soybean mosaic virus in soybean using genome editing technology
- Molecular characterization of viral pathogens on horticultural crops such as greenhouse vegetables, strawberries and cherry/apple trees, and development of IPM-based strategies to control them
- Better understanding of the virus infection process and molecular virus-host interactions for the development of novle antivral technologies.
Research and/or project statements
- Identification of novel host factors required for virus infection
- Identification of novel functional roles of virus-encoded proteins
- Novel discoveries in the co-evolutionary arms race between viruses and plant hosts
- Identification of newly emerging viruses infecting greenhouse vegetables and field crops in Canada
Professional activities / interests
- Understanding of molecular virus-plant interactions and virus genome expression and replication mechanism
- Molecular isolation of host factors and natural resistance genes
- Development of novel antiviral strategies through biotechnology and beneficial uses of plant viruses
- Training PhD students and postdoctoral scientists
Education and awards
PhD, the University of British Columbia in 1999
Gold Harvest (Innovation and Excellence), Agriculture and Agri-Food Canada in 2010
Queen Elizabeth II Diamond Jubilee Medal, Government of Canada in 2013
Outstanding Research Award, the Canadian Phytopathological Society in 2019
Ruth Allen Award, the American Phytopathological Society in 2019
International experience and/or work
Collaborative research being carried out with colleagues in China, the United States, Spain and France
Key publications
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Chai, M., Wu, X., Liu, J., Fang, Y., Luan, Y., Cui, X., Zhou, X., Wang, A., Cheng, X. (2020). P3N-PIPO interacts with P3 via the shared N-Terminal domain to recruit viral replication vesicles for cell-to-cell movement, 94(8), http://dx.doi.org/10.1128/JVI.01898-19
2020 - View publication details
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Cui, H., Li, Y., Wang, A. 2172 155-163. http://dx.doi.org/10.1007/978-1-0716-0751-0_12
2020 - View publication details
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Wu, G., Cui, X., Dai, Z., He, R., Li, Y., Yu, K., Bernards, M., Chen, X., Wang, A. (2020). A plant RNA virus hijacks endocytic proteins to establish its infection in plants, 101(2), 384-400. http://dx.doi.org/10.1111/tpj.14549
2020 - View publication details
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Griffiths, J., Lofano, A., Ellouze, W., Wang, A. (2019) Apple and apricot decline in Ontario. Plant Canada 2019, July 7-10. University of Guelph, Guelph, Ontario, Canada.
2019 - View publication details
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Towards Development of Next Generation Resistance to Soybean Mosaic Virus. Kangfu Yu and Aiming Wang. Plant Biology Europe 2018, Copenhagen, Denmark. On June 17-21, 2018.
2018 - View publication details
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Wang AM (2018) Virus and Host Plant Interactions. eLS. doi: 10.1002/9780470015902.a0000758.pub3John Wiley & Sons Ltd, Chichester. http://www.els.net
2018 - View publication details
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Park, S.H., Elhiti, M., Wang, H., Xu, A., Brown, D., Wang, A. (2017). Adventitious root formation of in vitro peach shoots is regulated by auxin and ethylene, 226 250-260. http://dx.doi.org/10.1016/j.scienta.2017.08.053
2017 - View publication details
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Park, S.H., Li, F., Renaud, J., Shen, W., Li, Y., Guo, L., Cui, H., Sumarah, M., Wang, A. (2017). NbEXPA1, an α-expansin, is plasmodesmata-specific and a novel host factor for potyviral infection, 92(5), 846-861. http://dx.doi.org/10.1111/tpj.13723
2017 - View publication details
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T. Bashar, R. Belfrage, J. McNeil, M. Bernards, K. Yu, and A. Wang. 2017.A Study on Soybean Mosaic Virus Transmission via Soybean Seeds. Plant Biology 2017. June 24-28, Honolulu, Hawaii, U.S.A.
2017 - View publication details
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Chen, H., Adam Arsovski, A., Yu, K., Wang, A. (2017). Deep sequencing leads to the identification of eukaryotic translation initiation factor 5A as a key element in Rsv1-mediated lethal systemic hypersensitive response to Soybean mosaic virus infection in soybean, 18(3), 391-404. http://dx.doi.org/10.1111/mpp.12407
2017 - View publication details
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Wylie, S.J., Adams, M., Chalam, C., Kreuze, J., López-Moya, J.J., Ohshima, K., Praveen, S., Rabenstein, F., Stenger, D., Wang, A., Zerbini, F.M. (2017). ICTV virus taxonomy profile: Potyviridae, 98(3), 352-354. http://dx.doi.org/10.1099/jgv.0.000740
2017 - View publication details
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Cui, H., Wang, A. (2017). An efficient viral vector for functional genomic studies of Prunus fruit trees and its induced resistance to Plum pox virus via silencing of a host factor gene, 15(3), 344-356. http://dx.doi.org/10.1111/pbi.12629
2017 - View publication details
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Cheng, X., Xiong, R., Li, Y., Li, F., Zhou, X., and Wang, A.M. (2017). "Sumoylation of the Turnip mosaic virus RNA polymerase promotes viral infection by counteracting the host NPR1-mediated immune response.", Plant Cell. doi: http://dx.doi.org/10.1105/tpc.16.00774
2017 - View publication details
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Li, F., Zhao, N., Li, Z., Xu, X., Wang, Y., Yang, X., Liu, S.S., Wang, A., Zhou, X. (2017). A calmodulin-like protein suppresses RNA silencing and promotes geminivirus infection by degrading SGS3 via the autophagy pathway in Nicotiana benthamiana, 13(2), http://dx.doi.org/10.1371/journal.ppat.1006213
2017 - View publication details
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Cheng, X., Wang, A. (2017). The potyvirus silencing suppressor protein VPg mediates degradation of SGS3 via ubiquitination and autophagy pathways, 91(1), http://dx.doi.org/10.1128/JVI.01478-16
2017 - View publication details
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Wang, A.M. and Zhou, X. (2016). "Preface.", in Wang, A. and Zhou, X. (eds.) - Current Research Topics in Plant Virology, Springer, pp. 5-6.
2016 - View publication details
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Wang, A.M. and Zhou, X. (2016). Current Research Topics in Plant Virology., Springer. (Book)
2016 - View publication details
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Wang, A.M. and Cui, H.G. (2016). "The Plum pox virus 6K1 protein is required for viral replication and targets the viral replication complex at the early infection stage.", 9th European Congress of Virology, Hamburg, Germany, October 19-22, 2016.
2016 - View publication details
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Wang, A.M. (2016). "Developing Next Generation Resistance to Plant Viral Diseases.", 5th Fuzhou International Symposium of Plant Pathology, Fuzhou, China, August 21-23, 2016
2016 - View publication details
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Wang, A.M. (2016). "Future Perspectives of Plant-Virus-Host Interactions.", 5th Fuzhou International Symposium of Plant Pathology. Fuzhou, China, August 21-23, 2016.
2016 - View publication details
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Contact
Research facility
Affiliations
- Adjunct Professor, Department of Biology, University of Western Ontario
- Senior Editor, Molecular Plant-Microbe Interactions (MPMI)
- Associate Editor, PLoS Pathogenes
- Editorial Board Member of Journal of Virology, Scientific Reports, Molecular Plant Pathology, Virology, and Soybean Science
- Lifetime Member, American Society for Virology
- Full Member, International Society for Molecular Plant-Microbe Interactions
- Member of International Plum Pox Virus Scientific Committee
- Memebr of Potyviridae Study Group, International Committee on Taxonomy on Viruses
- Member of Bromoviridae Study Group, International Committee on Taxonomy on Viruses